The Prostate Cancer gene 3 assay: Indications for use in clinical practice

BJU International

Volumn 105, Issue 4, 2010, Pages 452-455

  Schilling, David ^a   De Reijke, Theo ^b   Tombal, Bertrand ^c   De La Taille, Alexandre ^d   Hennenlotter, Jörg ^a   Stenzl, Arnulf ^a  

^a UNIVERSITY HOSPITAL TÜBINGEN   (Germany)

^b ACADEMIC MEDICAL CENTER   (Netherlands)

^c CLINIQUES UNIVERSITAIRES SAINT LUC   (Belgium)

^d HENRI MONDOR HOSPITAL   (France)

Author keywords

Clinical practice; PCA3; Prostate biopsy; Prostate cancer; PSA; Treatment decision

Indexed keywords

PROSTATE SPECIFIC ANTIGEN;

ADULT; CANCER SIZE; CLINICAL ARTICLE; CLINICAL DECISION MAKING; CLINICAL PRACTICE; DIAGNOSTIC ACCURACY; DIGITAL RECTAL EXAMINATION; FAMILY HISTORY; GENETIC ANALYSIS; HUMAN; MALE; PRIORITY JOURNAL; PROSTATE BIOPSY; PROSTATE CANCER; PROSTATE CANCER GENE 3; PROSTATE CANCER GENE 3 ASSAY; PROSTATECTOMY; SHORT SURVEY; TUMOR GENE;

AGED; ANTIGENS, NEOPLASM; BIOPSY; HUMANS; MALE; MIDDLE AGED; PROSTATE; PROSTATE-SPECIFIC ANTIGEN; PROSTATIC NEOPLASMS; TUMOR MARKERS, BIOLOGICAL;

EID: 76149145039     PISSN: 14644096     EISSN: 1464410X     Source Type: Journal    
DOI: 10.1111/j.1464-410X.2009.09085.x     Document Type: Short Survey

References (20)

1. Tombal B. Over- and underdiagnosis of prostate cancer: the dangers. Eur Urol Suppl 2006 5 : 511 513
2. Bozeman CB, Carver BS, Caldito G, Venable DD, Eastham JA. Prostate cancer in patients with an abnormal digital rectal examination and serum prostate-specific antigen less than 4.0 ng/mL. Urology 2005 66 : 803 807
3. Vollmer RT. Predictive probability of serum prostate-specific antigen for prostate cancer: an approach using Bayes rule. Am J Clin Pathol 2006 125 : 336 342
4. Seitz C, Palermo S, Djavan B. Prostate biopsy. Minerva Urol Nefrol 2003 55 : 205 218
5. Raja J, Ramachandran N, Munneke G, Patel U. Current status of transrectal ultrasound-guided prostate biopsy in the diagnosis of prostate cancer. Clin Radiol 2006 61 : 142 153
6. Groskopf J, Aubin SM, Deras IL et al. APTIMA PCA3 molecular urine test: development of a method to aid in the diagnosis of prostate cancer. Clin Chem 2006 52 : 1089 1095
7. TM PCA3 test for prostate cancer detection. Expert Rev Mol Diagn 2007 7 : 491 497
8. Haese A, de la Taille A, Van Poppel H et al. Clinical utility of the PCA3 urine assay in European men scheduled for repeat biopsy. Eur Urol 2008 54 : 1081 1088
9. Marks LS, Fradet Y, Deras IL et al. PCA3 molecular urine assay for prostate cancer in men undergoing repeat biopsy. Urology 2007 69 : 532 535
10. Deras IL, Aubin SM, Blase A et al. PCA3: a molecular urine assay for predicting prostate biopsy outcome. J Urol 2008 179 : 1587 1592
11. Nakanishi H, Groskopf J, Fritsche HA et al. PCA3 molecular urine assay correlates with prostate cancer tumor volume: implication in selecting candidates for active surveillance. J Urol 2008 179 : 1804 1809
12. Thompson IM, Pauler DK, Goodman PJ et al. Prevalence of prostate cancer among men with a prostate-specific antigen level < or = 4.0 ng per milliliter. N Engl J Med 2004 350 : 2239 2246
13. Postma R, Schröder FH. Screening for prostate cancer. Eur J Cancer 2005 41 : 825 833
14. de la Taille A, Irani J, de Reijke T, Haese A. Improved prediction of biopsy outcome using Prostate Cancer gene 3 (PCA3) in men undergoing an initial biopsy. Eur Urol Suppl 2009 8 : 193, Abstract 292
15. Heidenreich A, Aus G, Bolla M et al. EAU Guidelines on Prostate Cancer. Eur Urol 2008 53 : 68 80
16. Latini DM, Hart SL, Knight SJ et al. The relationship between anxiety and time to treatment for patients with prostate cancer on surveillance. J Urol 2007 178 : 826 831
17. Whitman EJ, Groskopf J, Ali A et al. PCA3 score before radical prostatectomy predicts extracapsular extension and tumor volume. J Urol 2008 180 : 1975 1978
18. Ankerst DP, Groskopf J, Day JR et al. Predicting prostate cancer risk through incorporation of prostate cancer gene 3. J Urol 2008 180 : 1303 1308
19. Chun FK, de la Taille A, Van Poppel H et al. Prostate cancer gene 3 (PCA3): development and internal validation of a novel biopsy nomogram. Eur Urol 2009 56 : 659 668
20. Kirby RS, Fitzpatrick JM, Irani J. Prostate cancer diagnosis in the new millennium: strengths and weaknesses of prostate-specific antigen and the discovery and clinical evaluation of prostate cancer gene 3 (PCA3). BJU Int 2009 103 : 441 445