Gamma-linolenic acid inhibits inflammatory responses by regulating nf-κB and AP-1 activation in lipopolysaccharide-induced RAW 264.7 macrophages

Inflammation

Volumn 33, Issue 1, 2010, Pages 46-57

  Chang, Cheng Sue ^a   Sun, Hai Lun ^b,c   Lii, Chong Kuei ^d   Chen, Haw Wen ^d   Chen, Pei Yin ^c   Liu, Kai Li ^b,c  

^a CHANGHUA CHRISTIAN HOSPITAL   (Taiwan)

^b CHUNG SHAN MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^c CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

^d CHINA MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Gamma linolenic acid; Inflammation; Linoleic acid; Lipopolysaccharides; Mouse RAW 264.7 macrophages

Indexed keywords

CYCLOOXYGENASE 2; GAMMA LINOLENIC ACID; GLUTATHIONE; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; LINOLEIC ACID; LIPOPOLYSACCHARIDE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; NUCLEAR PROTEIN; STRESS ACTIVATED PROTEIN KINASE 1; TRANSCRIPTION FACTOR AP 1;

ANIMAL CELL; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; DNA BINDING; GENE ACTIVITY; INFLAMMATION; MACROPHAGE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REPORTER GENE; SIGNAL TRANSDUCTION;

ANIMALS; ANTI-INFLAMMATORY AGENTS; CELL LINE; CELL SURVIVAL; CYCLOOXYGENASE 2; DOSE-RESPONSE RELATIONSHIP, DRUG; GAMMA-LINOLENIC ACID; GLUTATHIONE; I-KAPPA B KINASE; INFLAMMATION; INTERLEUKIN-1; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASE 8; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; PHOSPHORYLATION; PROTEIN PRECURSORS; RNA, MESSENGER; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTOR AP-1; TRANSCRIPTION FACTOR RELA;

EID: 76149140866     PISSN: 03603997     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10753-009-9157-8     Document Type: Article

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