Use of a combination of lsotopically coded cross-linkers and lsotopically coded N-terminal modification reagents for selective identification of inter-peptide crosslinks

Analytical Chemistry

Volumn 82, Issue 3, 2010, Pages 817-823

  Petrotchenko, Evgeniy V ^a   Serpa, Jason J ^a   Borchers, Christoph H ^a  

^a UNIVERSITY OF VICTORIA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO GROUP; AMINO TERMINUS; ANALYTICAL CHALLENGE; CRITICAL DISTANCE; CROSS-LINKED PROTEINS; CROSS-LINKERS; CROSSLINKS; DATA ANALYSIS; ENZYMATIC DIGESTIONS; EXPERIMENTAL DATA; ISOTOPIC SIGNATURES; LYSINE RESIDUES; N-TERMINALS; PEPTIDE MIXTURES; PROTEIN ASSEMBLY; PROTEOMICS; RAPID METHOD; SPECIALIZED SOFTWARE; SPECIFIC DETECTION; THREE-DIMENSIONAL STRUCTURE;

AMINO ACIDS; COMPUTER SOFTWARE; MASS SPECTROMETRY; MOLECULAR BIOLOGY;

PEPTIDES;

CROSS LINKING REAGENT; PEPTIDE; RNA DIRECTED DNA POLYMERASE;

AMINO ACID SEQUENCE; ARTICLE; CHEMISTRY; COMPUTER PROGRAM; HUMAN; ISOTOPE LABELING; MASS SPECTROMETRY; METHODOLOGY; MOLECULAR GENETICS; PROTEIN TERTIARY STRUCTURE; PROTEOMICS;

AMINO ACID SEQUENCE; CROSS-LINKING REAGENTS; HIV REVERSE TRANSCRIPTASE; HUMANS; ISOTOPE LABELING; MOLECULAR SEQUENCE DATA; PEPTIDES; PROTEIN STRUCTURE, TERTIARY; PROTEOMICS; SOFTWARE; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;

EID: 76149136920     PISSN: 00032700     EISSN: None     Source Type: Journal    
DOI: 10.1021/ac901637v     Document Type: Article

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