Wernicke's encephalopathy: Role of thiamine

Practical Gastroenterology

Volumn 33, Issue 6, 2009, Pages

  Thomson, Allan D ^a,b   Guerrini, Irene ^b,c   Marshall, E Jane ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

^c SOUTH LONDON AND MAUDSLEY NHS FOUNDATION TRUST   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ELECTROLYTE; INFUSION FLUID; MAGNESIUM; PHOSPHATE; POTASSIUM; THIAMINE;

ALCOHOL CONSUMPTION; ANAPHYLAXIS; ARTICLE; DIETARY INTAKE; DRUG HYPERSENSITIVITY; FLUID THERAPY; HEPATIC ENCEPHALOPATHY; HUMAN; MORBIDITY; MORTALITY; NUTRITIONAL DEFICIENCY; PROPHYLAXIS; PRURITUS; SUBSTITUTION THERAPY; THIAMINE DEFICIENCY; TREATMENT FAILURE; VITAMIN SUPPLEMENTATION; WERNICKE ENCEPHALOPATHY; WERNICKE KORSAKOFF SYNDROME;

EID: 76149131328     PISSN: 02774208     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (35)

1. Cook CC, Hallwood PM, Thomson AD. B-vitamin deficiency and neuro-psychiatric syndromes in alcohol misuse. Alcohol Alcohol, 1998:33:317-336.
2. Thomson AD, Cook CCH, Guerrini I, et al. Wernicke's encephalopathy: plus ca change, plus c'est la meme chose. Alcohol Alcohol, 2008;43:180-186.
3. De Wardener HE, Lennox B. Cerebral beriberi (Wernicke's Encephalopathy): review of 52 cases in a Singapore prisoner-of-war hospital. Lancet, 1947;1:11-17.
4. Thomson AD, Cook, CCH, Touquet R, et al. The Royal College of Physicians report on alcohol: guidelines for managing Wernicke's encephalopathy in the accident and emergency department. Alcohol Alcohol, 2002;37:513-521.
5. Harper C. The incidence of Wernicke's encephalopathy in Australia: a neuropathological study of 131 cases. J Neurol Neurosurg Psych, 1983;46:593-598.
6. Day E, Bentham P, Callaghan R, et al. Thiamine for Wernicke-Korsakoff Syndrome in people at risk from alcohol abuse. Cochrane Database of Systematic Reviews, Issue 1, 2009, CD004033.pub2.
7. Victor M, Adams RD, Collins GH. The Wernicke-Korsakoff Syndrome and Related Neurological Disorders due to Alcoholism and Malnutrition. In: Contemporary Neurology Series, 2nd Edition. F.A. Davis, Philadelphia, PA, 1989.
8. Victor M, Adams RD, Collins GH. The Wernicke-Korsakoff Syndrome, F.A. Davis, Philadelphia PA, 1971.
9. Thomson AD, Marshall EJ. The natural history of Wernicke's encephalopathy and Korsakoff's Psychosis. Alcohol Alcohol, 2006;41:151-158.
10. Thomson AD. Mechanisms of vitamin deficiency in chronic alcohol misusers and the development of the Wernicke-Korsakoff Syndrome. Alcohol Alcohol, 2000;35(Suppl. 1):2-7.
11. Thomson AD, Frank O, Baker H, et al. Thiamine propyl disulfide: absorption and utilization. Ann Intern Med, 1971;74: 529-534.
12. Guerrini I, Thomson AD, Gurling HM. Molecular Genetics of Alcohol Related Brain Damage. Alcohol Alcohol, 2009;44(2): 166-170. Advance Access published on December 18, 2008.
13. Thomson AD, Jeyasingham M, Pratt OE, et al. Nutrition and alcoholic encephalopathies. Acta Med Scand Supplementum, 1987;717:55-65.
14. Mancinelli R, Ceccanti M, Guiducci MS, et al. Simultaneus liquid chromatographic assessment of thiamine, thiamine monophosphate and thiamine diphosphate in human erythrocytes: a study on alcoholics. J Chrom B, 2003;789:355-363.
15. Ceccanti M, Mancinelli R, Sasso GF, et al. Erythrocyte thiamine (Th) esters: a major factor of the alcohol withdrawal syndrome or a candidate marker for alcoholism itself. Alcohol Alcohol, 2005;40(4):283-290.
16. Thomson AD, Cook CC, Guerrini I, et al. Wernicke's encephalopathy revisited. Translation of the case history section of the original manuscript by Carl Wernicke "Lehrbuch der Gehirnkrankheiten fur Aerzte and Studirende" (1881) with a commentary. Alcohol Alcohol, 2008;43:174-179.
17. Harper CG, Giles M, Finlay-Jones R. Clinical signs of the Wernicke-Korsakoff complex: a retrospective analysis of 131 cases diagnosed at necropsy. J Neurol Neurosurg Psych, 1986; 49:341-345.
18. Caine D, Halliday GM, Kril JJ, et al. Operational criteria for the classification of chronic alcoholics: identification of Wernicke's encephalopathy. J Neurol Neurosurg Psych, 1997;62:51-60.
19. Sullivan EV, Pfefferbaum A. Neuroimaging of the Wernicke-Korsakoff Syndrome. Alcohol Alcohol, 2009;44:155-165.
20. Baker H, Frank O, Zetterman RK, et al. Inability of chronic alcoholics with liver disease to use food as a source of folates, thiamine and vitamin B6. Am J Clin Nutr, 1975;28: 1377-1380.
21. Chataway J, Hardman E. Thiamine in Wernicke's syndrome - how much and how long? Postgrad Med J, 1995;71:249.
22. Thomson AD, Marshall EJ. The Treatment of Patients at risk of developing Wernicke's Encephalopathy in the Community. Alcohol Alcohol, 2006;41:159-167.
23. Royal College of Physicians 2001. Report of the Working Party: Alcohol-can the NHS afford it? Recommendations for a coherent alcohol strategy for hospitals, Royal College of Physicians, London.
24. Wood B, Currie J, Breen K. Wernicke's encephalopathy in a metropolitan hospital: a prospective study of the incidence, characteristics and outcome. Med J Aust, 1986;144: 12-16.
25. Nakada T, Knight RT. Alcohol and the Central Nervous System. Med Clin North Am, 1984;68:121-131.
26. Lindberg MC, Oyler RA. Wernicke's Encephalopathy. Am Fam Physician, 1990;41: 1205-1209.
27. British National Formulary (BNF) British Medical Association; Royal Pharmaceutical Society of Great Britain.2009. bnf.org
28. Lingford-Hughes AR, Welch S, Nutt DJ. Evidence based guidelines for the pharmacological management of substance misuse, addiction and comorbidity: recommendations from the British Association for Psychopharmacology. J Psychopharmacol, 2004;18(3):293-335.
29. Charness ME. Alcohol. In Noseworthy, J. Neurological Therapeutics. Martin Dunitz, London, 2006, 1677-1685.
30. Sechi G, Serra A. Wernicke's encephalopathy: new clinical settings and recent advances in diagnosis and management. Lancet Neurol, 2007;6(5):442-455.
31. Wrenn KD, Murphy F, Slovis CM. A toxicity study of parenteral thiamine hydrochloride. Ann Emerg Med, 1989;18: 867-870.
32. Wrenn KD, Slovis CM. Is intravenous thiamine safe? Am J Am Med, 1992;10:165.
33. Flink EB. Therapy of magnesium deficiency. Ann NY Acad Sci, 1969;162:901-905.
34. Moss M, Burnham EL. Alcohol abuse in the critically ill patient. Lancet, 2006;368:2231-2242.
35. Kopelman MD, Thomson AD, Guerrini I, Marshall EJ. The Korsakoff Syndrome: Clinical Aspects, Psychology and Treatment. Alcohol Alcohol, 2009;44:148-154.