Prospective study into the incidence of lambert eaton myasthenic syndrome in small cell lung cancer

Journal of Thoracic Oncology

Volumn 5, Issue 1, 2010, Pages 34-38

  Payne, Miranda ^a   Bradbury, Penny ^b   Lang, Bethan ^c   Vincent, Angela ^c   Han, Cheng ^a   Newsom Davis, John ^d   Talbot, Denis ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b PRINCESS MARGARET HOSPITAL   (Canada)

^c UNIVERSITY OF OXFORD   (United Kingdom)

^d OXFORD UNIVERSITY HOSPITALS NHS FOUNDATION TRUST   (United Kingdom)

Author keywords

Lambert Eaton myasthenic syndrome; Small cell lung cancer; Voltage gated calcium channel antibodies (VGCC).

Indexed keywords

VOLTAGE GATED CALCIUM CHANNEL;

ADULT; AGED; ARTICLE; CEREBELLAR ATAXIA; CONTROLLED STUDY; EATON LAMBERT SYNDROME; FEMALE; HUMAN; INCIDENCE; LUNG SMALL CELL CANCER; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RADIOIMMUNOASSAY; SURVIVAL RATE;

EID: 76149125790     PISSN: 15560864     EISSN: 15561380     Source Type: Journal    
DOI: 10.1097/JTO.0b013e3181c3f4f1     Document Type: Article

References (21)

1. Parkin DM, Bray F, Ferlay J, et al. Global cancer statistics, 2002. CA Cancer J Clin 2005;55:74-108.
2. Govindan R, Page N, Morgensztern D, et al. Changing epidemiology of small-cell lung cancer in the United States over the last 30 years: analysis of the surveillance, epidemiologic, and end results database. J Clin Oncol 2006;24:4539-4544.
3. Hawley RJ, Cohen MH, Saini N, et al. The carcinomatous neuromyopathy of oat cell lung cancer. Ann Neurol 1980;7:65-72.
4. de la Monte SM, Hutchins GM, Moore GW, et al. Paraneoplastic syndromes and constitutional symptoms in prediction of metastatic behavior of small cell carcinoma of the lung. Am J Med 1984;77:851-857.
5. O'Neill JH, Murray NM, Newsom-Davis J, et al. The Lambert-Eaton myasthenic syndrome. A review of 50 cases. Brain 1988;111 (Pt 3):577-596.
6. Elrington GM, Murray NM, Spiro SG, et al. Neurological paraneoplastic syndromes in patients with small cell lung cancer. A prospective survey of 150 patients. J Neurol Neurosurg Psychiatry 1991;54: 764-767.
7. Posner JB. Paraneoplastic syndromes. Neurol Clin 1991;9:919-936.
8. Lang B, Newsom-Davis J. Immunopathology of the Lambert-Eaton myasthenic syndrome. Springer Semin Immunopathol 1995;17:3-15.
9. McCann FV, Pettengill OS, Cole JJ, et al. Calcium spike electrogenesis and other electrical activity in continuously cultured small cell carcinoma of the lung. Science 1981;212:1155-1157.
10. Roberts A, Perera S, Lang B, et al. Paraneoplastic myasthenic syndrome IgG inhibits 45Ca2+ flux in a human small cell carcinoma line. Nature 1985;317:737-739.
11. Motomura M, Johnston I, Lang B, et al. An improved diagnostic assay for Lambert-Eaton myasthenic syndrome. J Neurol Neurosurg Psychiatry 1995;58:85-87.
12. Lennon VA, Kryzer TJ, Griesmann GE, et al. Calcium-channel antibodies in the Lambert-Eaton syndrome and other paraneoplastic syndromes. N Engl J Med 1995;332:1467-1474.
13. Nakao YK, Motomura M, Fukudome T, et al. Seronegative Lambert- Eaton myasthenic syndrome: study of 110 Japanese patients. Neurology 2002;59:1773-1775.
14. Sabater L, Titulaer M, Saiz A, et al. SOX1 antibodies are markers of paraneoplastic Lambert-Eaton myasthenic syndrome. Neurology 2008; 70:924-928.
15. Graus F, Lang B, Pozo-Rosich P, et al. P/Q type calcium-channel antibodies in paraneoplastic cerebellar degeneration with lung cancer. Neurology 2002;59:764-766.
16. Monstad SE, Drivsholm L, Storstein A, et al. Hu and voltage-gated calcium channel (VGCC) antibodies related to the prognosis of smallcell lung cancer. J Clin Oncol 2004;22:795-800.
17. Maddison P, Newsom-Davis J, Mills KR, et al. Favourable prognosis in Lambert-Eaton myasthenic syndrome and small-cell lung carcinoma. Lancet 1999;353:117-118.
18. Wirtz PW, Lang B, Graus F, et al. P/Q-type calcium channel antibodies, Lambert-Eaton myasthenic syndrome and survival in small cell lung cancer. J Neuroimmunol 2005;164:161-165. (Pubitemid 40826775)
19. Eaton LM, Lambert EH. Electromyography and electric stimulation of nerves in diseases of motor unit; observations on myasthenic syndrome associated with malignant tumors. J Am Med Assoc 1957;163:1117-1124.
20. Newsom-Davis J, Murray N, Wray D, et al. Lambert-Eaton myasthenic syndrome: electrophysiological evidence for a humoral factor. Muscle Nerve 1982;5:S17-S20.
21. Rooke ED, Eaton LM, Lambert EH, et al. Myasthenia and malignant intrathoracic tumor. Med Clin North Am 1960;44:977-988.