An evaluation of paper chromatography for measuring the levels of radiochemical impurities in 99mTc Medronate Injection

Journal of Labelled Compounds and Radiopharmaceuticals

Volumn 53, Issue 1, 2010, Pages 11-14

  Millar, Alistair M ^a   O'Brien, Lesley M ^a   Beattie, Lynn A ^a   Craig, Fiona ^a  

^a ROYAL INFIRMARY OF EDINBURGH   (United Kingdom)

Author keywords

Paper chromatography; Radiochemical purity

Indexed keywords

IMPURITIES; KETONES; PAPER; SILICA GEL; SODIUM COMPOUNDS;

CHROMATOGRAPHY PAPER; EUROPEAN PHARMACOPOEIAS; IMPURITIES IN; IMPURITY PEAKS; PALL CORPORATIONS; PAPER CHROMATOGRAPHY; PERTECHNETATE; RADIOCHEMICAL PURITY; STATIONARY PHASE; THIN-LAYER CHROMATOGRAPHY;

THIN LAYER CHROMATOGRAPHY;

2 BUTANONE; ACETIC ACID; COLLOID TC 99M; MEDRONATE TECHNETIUM TC 99M; PERTECHNETIC ACID TC 99M;

ARTICLE; ARTIFACT; CONTROLLED STUDY; DRUG IMPURITY; INTERMETHOD COMPARISON; PAPER; PAPER CHROMATOGRAPHY; RADIOCHEMISTRY; THIN LAYER CHROMATOGRAPHY;

EID: 76149122846     PISSN: 03624803     EISSN: 10991344     Source Type: Journal    
DOI: 10.1002/jlcr.1693     Document Type: Article

References (5)

1. European Directorate for the Quality of Medicines, European Pharmacopoeia, 5th edn, European Directorate for the Quality of Medicines, 2004.
2. A. M. Millar, L. A. Beattie, F. Craig, L. M. O'Brien, J. Label. Compd. Radiopharm. 2009, DOI: 10.1002/jlcr.1671.
3. A. M. Zimmer, D. G. Pavel, J. Nucl. Med. 1977, 18, 1230.
4. Cellulose chromatography papers, Whatman plc, Maidstone, UK, 2009.
5. L. A. Beattie, L. M. O'Brien, A. M. Millar, Nucl. Med. Commun. 2008, 29, 487.