Mucosal expression of nerve growth factor and brainderived neurotrophic factor in chronic rhinosinusitis

American Journal of Rhinology and Allergy

Volumn 23, Issue 6, 2009, Pages 571-574

  Coffey, Charles S ^a   Mulligan, Ryan M ^a   Schlosser, Rodney J ^a  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

Allergy; BDNF; Brain derived neurotrophic factor; Chronic rhinosinusitis; Nerve growth factor; Neural hyperresponsiveness; Neurogenic inflammation; Neurotrophins; NGF; Polyp

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; NERVE GROWTH FACTOR;

ADOLESCENT; ADULT; AGED; ARTICLE; ATOPY; CHILD; CHRONIC DISEASE; CLINICAL ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN TISSUE; NOSE POLYP; PARANASAL SINUS; PRESCHOOL CHILD; PROTEIN EXPRESSION; RHINOSINUSITIS; SCHOOL CHILD; TISSUE LEVEL; TURBINATE;

ADOLESCENT; ADULT; AGED; BRAIN-DERIVED NEUROTROPHIC FACTOR; CHILD; CHILD, PRESCHOOL; CHRONIC DISEASE; FEMALE; GENE EXPRESSION REGULATION; HUMANS; MALE; MIDDLE AGED; MUCOUS MEMBRANE; NASAL POLYPS; NERVE GROWTH FACTOR; NEUROIMMUNOMODULATION; PARANASAL SINUSES; RHINITIS; SINUSITIS; TISSUE EXTRACTS;

EID: 76149122839     PISSN: 19458924     EISSN: 19458932     Source Type: Journal    
DOI: 10.2500/ajra.2009.23.3412     Document Type: Article

References (13)

1. Diemer FB, Sanico AM, Horowitz E, et al. Non-allergenic inhalant triggers in seasonal and perennial allergic rhinitis. J Allergy Clin Immunol 103:S2, 1999.
2. Lal D, and Corey JP. Vasomotor rhinitis update. Curr Opin Otolaryngol Head Neck Surg 12:243-247, 2004.
3. Tai CF, and Baraniuk JN. Upper airway neurogenic mechanisms. Curr Opin Allergy Clin Immunol 2:11-19, 2002.
4. Sarin S, Undem B, Sanico A, et al. The role of the nervous system in rhinitis. J Allergy Clin Immunol 118:999-1014, 2006.
5. Sanico AM, Koliatsos VE, Stanisz AM, et al. Neural hyperresponsiveness and nerve growth factor in allergic rhinitis. Int Arch Allergy Immunol 118:153-158, 1999.
6. O'Hanlon S, Facer P, Simpson KD, et al. Neuronal markers in allergic rhinitis: Expression and correlation with sensory testing. Laryngoscope 117:1519-1527, 2007.
7. Kimata H. Brain-derived neurotrophic factor selectively enhances allergen-specific IgE production. Neuropeptides 39:379-383, 2005.
8. Raap U, Fokkens W, Bruder M, et al. Modulation of neurotrophin and neurotrophin receptor expression in nasal mucosa after nasal allergen provocation in allergic rhinitis. Allergy 63:468-475, 2008.
9. Sanico AM, Stanisz AM, Gleeson TD, et al. Nerve growth factor expression and release in allergic inflammatory disease of the upper airways. Am J Respir Crit Care Med 161:1631-1635, 2000.
10. Wu XQ, Myers AC, Goldstone AC, et al. Localization of nerve growth factor and its receptors in the human nasal mucosa. J Allergy Clin Immunol 118:428-433, 2006.
11. Lommatzsch M, Braun A, and Renz H. Neurotrophins in allergic airway dysfunction: What the mouse model is teaching us. Ann N Y Acad Sci 992:241-249, 2003.
12. Jornot L, Grouzmann E, Lacroix JS, et al. BDNF and DDP-IV in polyps and middle turbinates epithelial cells. Rhinology 45:129-133, 2007.
13. Braun A, Lommatzsch M, Neuhaus-Steinmetz U, et al. Brain-derived neurotrophic factor (BDNF) contributes to neuronal dysfunction in a model of allergic airway inflammation. Br J Pharmacol 141:431-440, 2004.