Measuring linezolid in biological fluids using high-efficiency liquid chromatography;Determinación de linezolid en fluidos biológicos mediante cromatografía líquida de alta eficacia

Farmacia Hospitalaria

Volumn 34, Issue 1, 2010, Pages 27-31

  Guerrero, L ^a   Sarasa, M ^b   Lopez Y ^a   Soy, D ^a  

^a HOSPITAL CLÍNIC   (Spain)

^b Medical affairs Merck sharp and Dohme ltd   (Spain)

Author keywords

Cerebrospinal fluid; Chromatography high pressure liquid; Linezolid; Pharmacokinetics; Plasma; Vitreous humour

Indexed keywords

LINEZOLID;

ARTICLE; BIOLOGICAL MODEL; DRUG BLOOD LEVEL; DRUG CEREBROSPINAL FLUID LEVEL; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; VITREOUS BODY;

ACETAMIDES; ANTI-INFECTIVE AGENTS; CHROMATOGRAPHY, LIQUID; HUMANS; OXAZOLIDINONES; VITREOUS BODY;

EID: 76149104881     PISSN: 11306343     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.farma.2009.07.001     Document Type: Article

References (9)

1. Livermore D.M. Linezolid in vitro: Mechanism and antibacterial spectrum. J Antimicrob Chemother 51 (2003) ii9-ii16
2. Andes D., van Ogtrop M.L., Peng J., and Craig W.A. In vivo pharmacodynamics of a new oxazolidinona (Linezolid). Antimicrob Agents Chemother 46 (2002) 3484-3489
3. Gee T., Ellis R., Marshall G., Andrews J., Ashby J., and Wise R. Pharmacokinetics and tissue penetration of linezolid following multiple oral doses. Antimicrob Agents Chemother 45 (2001) 1843-1846
4. Mensa J., Soriano A., García E., and Moreno-Martínez A. Aspectos farmacocinéticos y farmacodinámicos de linezolid. Rev Esp Quimioterapia 15 (2002) 20-23
5. Tobin C.M., Sunderland J., White L.O., and MacGowan A.P. A simple isocratic high-performance liquid chromatography assay for linezolid in human serum. J Antimicrob Chemother 48 (2001) 605-608
6. Ehrlich M., Trittler R., Daschner F.D., and Kümmerer K. A new and rapid method for monitoring the new oxazolidinone antibiotic linezolid in serum and urine by high performance liquid chromatography-integrated sample preparation. J Chromatogr B Biomed Sci Appl 755 (2001) 373-377
7. Peng G.W., Stryd R.P., Murata S., Igarashi M., Chiba K., Aoyama H., et al. Determination of linezolid in plasma by reversed-phase high-performance liquid chromatography. J Pharm Biomed Anal 20 (1999) 65-73
8. Ross G.H., Gunderson B.W., Ibrahim K.H., Sullivan C.J., and Rotschafer J.C. Central nervous system infections. In: Dipiro J.R., Talbert R.L., Yee G.C., Matzke G.R., Wells B.G., and Posey L.M. (Eds). Pharmacotherapy. A pathophysiologic approach. 5 ed (2002), The MacGraw-Hill Companies Inc., New York (USA)
9. Asensio VM, Corral A, Aguirre B, De la Paz M. Amino acid concentrations in the vitreous body in control subjects. Arch Soc Esp Oftalmol [online] [consultado 2008/03/28]. Disponible en: http://scielo.isciii.es/scielo.php?script.ISSN 0365-6691.