Preadmission use of systemic glucocorticoids and 30-day mortality following bleeding peptic ulcer: A population-based cohort study

American Journal of Therapeutics

Volumn 17, Issue 1, 2010, Pages 23-29

  Olsen, Morten ^a   Christensen, Steffen ^a   Riis, Anders ^a   Thomsen, Reimar W ^a  

^a AARHUS UNIVERSITY HOSPITAL   (Denmark)

Author keywords

Glucocorticoids; Mortality; Peptic ulcer bleeding; Population based; Prognosis

Indexed keywords

ACETYLSALICYLIC ACID; ANTIDEPRESSANT AGENT; ANTIVITAMIN K; CALCIUM CHANNEL BLOCKING AGENT; GLUCOCORTICOID; HISTAMINE H2 RECEPTOR ANTAGONIST; NONSTEROID ANTIINFLAMMATORY AGENT; PROTON PUMP INHIBITOR;

ADULT; AGED; ARTICLE; COMORBIDITY; DRUG DOSE COMPARISON; DRUG MEGADOSE; DRUG USE; FOLLOW UP; HOSPITAL ADMISSION; HUMAN; LONG TERM CARE; LOW DRUG DOSE; MAJOR CLINICAL STUDY; MORTALITY; PEPTIC ULCER BLEEDING; PRIORITY JOURNAL; SHORT COURSE THERAPY; TREATMENT OUTCOME;

AGED; AGED, 80 AND OVER; COHORT STUDIES; DATABASES, FACTUAL; DENMARK; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; FEMALE; FOLLOW-UP STUDIES; GLUCOCORTICOIDS; HOSPITALIZATION; HUMANS; MALE; MIDDLE AGED; PEPTIC ULCER HEMORRHAGE;

EID: 76149101328     PISSN: 10752765     EISSN: None     Source Type: Journal    
DOI: 10.1097/MJT.0b013e318197c57c     Document Type: Article

References (25)

1. Nielsen GL, Sørensen HT, Mellemkjær L, et al. Risk of hospitalization resulting from upper gastrointestinal bleeding among patients taking corticosteroids: a register-based cohort study. Am J Med. 2001;11:541-545.
2. Kujath P, Schwandner O, Bruch HP. Morbidity and mortality of perforated peptic gastroduodenal ulcer following emergency surgery. Langenbecks Arch Surg. 2002; 387:298-302.
3. Christensen S, Riis A, Nørgaard M, et al. Perforated peptic ulcer: use of pre-admission oral glucocorticoids and 30-day mortality. Aliment Pharmacol Ther. 2006;23:45-52.
4. Messer J, Reitman D, Sacks HS. Association of adrenocorticosteroid therapy and peptic-ulcer disease. N Engl J Med. 1983;309:21-24.
5. Thomsen RW, Riis A, Christensen S, et al. Diabetes and 30-day mortality from peptic ulcer bleeding and perforation: a Danish population-based cohort study. Diabetes Care. 2006;29:805-810.
6. Leerdam ME, Vreeburg EM, Rauws EAJ, et al. Acute upper GI bleeding: did anything change? Time trend analysis of incidence and outcome of acute upper GI bleeding between 1993/1994 and 2000. Am J Gastroenterol. 2003;98:1494-1499.
7. Henry DA, Johnston A, Dobson A, et al. Fatal peptic ulcer complications and the use of non-steroidal antiinflammatory drugs, aspirin, and corticosteroids. BMJ. 1987;295:1227-1229.
8. Blatchford O, Davidson LA, Murray WR, et al. Acute upper gastrointestinal haemorrhage in west of Scotland: case ascertainment study. BMJ. 1997;315:510-514.
9. Klebl F, Bregenzer N, Schö fer L, et al. Risk factors for mortality in severe upper gastrointestinal bleeding. Int J Colorectal Dis. 2005;20:49-56.
10. Frank L. When an entire country is a cohort. Science. 2000; 287:2398-2399.
11. Thomsen RW, Riis A, Christensen S, et al. Outcome of peptic ulcer bleeding among users of traditional nonsteroidal anti-inflammatory drugs and selective cyclooxygenase-2 inhibitors. Aliment Pharmacol Ther. 2006;24: 1431-1438.
12. Andersen TF, Madsen M, Jørgensen J, et al. The Danish National Hospital Register: a valuable source of data for modern health sciences. Dan Med Bull. 1999;46:263-268.
13. Gaist D, Sørensen HT, Hallas J. The Danish prescription registries. Dan Med Bull. 1997;44:445-448.
14. Pødenphant J. Glukokortikoider. Available at: http://www.medicin. dk. Accessed October 27, 2008.
15. Charlson ME, Pompei P, Ales KL, et al. A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis. 1987;40: 373-383.
16. de Groot V, Beckerman H, Lankhorst GJ, et al. How to measure comorbidity: a critical review of available methods. J Clin Epidemiol. 2003;56:221-229.
17. Deyo RA, Cherkin DC, Ciol MA. Adapting a clinical comorbidity index for use with ICD-9-CM administrative databases. J Clin Epidemiol. 1992;45:613-619.
18. Cattaruzzi C, Troncon MG, Agostinis L, et al. Positive predictive value of ICD-9th codes for upper gastrointestinal bleeding and perforation in the Sistema Informativo Sanitario Regionale database. J Clin Epidemiol. 1999;52: 499-502.
19. Lassen A, Hallas J, De Muckadell OBS. Complicated and uncomplicated peptic ulcers in a Danish county 1993-2002: a population-based cohort study. Am J Gastroenterol. 2006;101:945-953.
20. Thomsen RW, Riis A, Munk EM, et al. 30-Day mortality after peptic ulcer perforation among users of newer selective COX-2 inhibitors and traditional NSAIDs: a population-based study. Am J Gastroenterol. 2006;101: 2704-2710.
21. Rockall TA, Logan RFA, Devlin HB, et al. Incidence of and mortality from acute upper gastrointestinal haemorrhage in the United Kingdom. BMJ. 1995;311:222-226.
22. Vreeburg EM, Snel P, de Bruijne JW, et al. Acute upper gastrointestinal bleeding in the Amsterdam area: incidence, diagnosis, and clinical outcome. Am J Gastroenterol. 1997;92:236-243
23. Schä cke H, Döcke WD, Asadullah K. Mechanisms involved in the side effects of glucocorticoids. Pharmacol Ther. 2002;96:23-43.
24. Luo JC, Shin VY, Liu ESL, et al. Dexamethasone delays ulcer healing by inhibition of angiogenesis in rat stomachs. Eur J Pharmacol. 2004;485:275-281.
25. Lin HJ, Wang K, Perng CL, et al. Early or delayed endoscopy for patients with peptic ulcer bleeding: a prospective randomized study. J Clin Gastroenterol. 1996; 22:267-271.