Development of novel bioadhesive buccal formulation of diltiazem: In vitro and in vivo characterization

PDA Journal of Pharmaceutical Science and Technology

Volumn 63, Issue 5, 2009, Pages 401-408

  Shayeda, ^a   Gannu, Ramesh ^a   Palem, Chinna Reddy ^a   Rao, Y Madhusudan ^a  

^a KAKATIYA UNIVERSITY   (India)

Author keywords

Bioadhesion; Buccal delivery; Buccal mucosa; Buccoadhesive; Diltiazem; Mucoadhesive

Indexed keywords

CARBOPOL 934; DILTIAZEM; DILZIM; HYDROXYPROPYLMETHYLCELLULOSE; POLYMER; UNCLASSIFIED DRUG;

ADHESION; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG FORMULATION; DRUG PENETRATION; DRUG RELEASE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; IN VITRO STUDY; IN VIVO STUDY; MALE; MAXIMUM PLASMA CONCENTRATION; NONHUMAN; PHYSICOCHEMICAL MODEL; TIME TO MAXIMUM PLASMA CONCENTRATION;

ABSORPTION; ACRYLATES; ADHESIVENESS; ADMINISTRATION, BUCCAL; ADULT; ANIMALS; AREA UNDER CURVE; BIOLOGICAL AVAILABILITY; CALCIUM CHANNEL BLOCKERS; CROSS-OVER STUDIES; DILTIAZEM; DRUG CARRIERS; HUMANS; MALE; METHYLCELLULOSE; MOUTH MUCOSA; SWINE; TABLETS; YOUNG ADULT;

EID: 76049125523     PISSN: 10797440     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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