Social isolation dysregulates endocrine and behavioral stress while increasing malignant burden of spontaneous mammary tumors

Proceedings of the National Academy of Sciences of the United States of America

Volumn 106, Issue 52, 2009, Pages 22393-22398

  Hermes, Gretchen L ^a,b   Delgado, Bertha ^a,c   Tretiakova, Maria ^a,c   Cavigelli, Sonia A ^a   Krausz, Thomas ^a,c   Conzen, Suzanne D ^a,c   McClintock, Martha K ^a,b,c  

^a UNIVERSITY OF CHICAGO   (United States)

^b UNIVERSITY OF CHICAGO   (United States)

^c UNIVERSITY OF CHICAGO   (United States)

Author keywords

Breast cancer; Glucocorticoids; Physiological stress; Psychological stress; Social behavior

Indexed keywords

CORTICOSTERONE; ESTROGEN; PROGESTERONE;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANXIETY; ARTICLE; BEHAVIORAL STRESS; BREAST TUMOR; CARCINOGENESIS; CONTROLLED STUDY; ENDOCRINE DISEASE; ESTROGEN BLOOD LEVEL; FEAR; FEMALE; GENETIC ANALYSIS; GENETIC RISK; HORMONE RESPONSE; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; INTRADUCTAL CARCINOMA; MENTAL STRESS; NONHUMAN; OVARY FUNCTION; PHENOTYPE; PRIORITY JOURNAL; PROGESTERONE BLOOD LEVEL; RAT; SOCIAL ISOLATION; SPRAGUE DAWLEY RAT; TUMOR GROWTH;

ANIMALS; BEHAVIOR, ANIMAL; BREAST NEOPLASMS; CARCINOMA, DUCTAL, BREAST; CARCINOMA, INTRADUCTAL, NONINFILTRATING; CORTICOSTERONE; ENDOCRINE GLANDS; FEMALE; HUMANS; MAMMARY NEOPLASMS, EXPERIMENTAL; OVARY; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, GLUCOCORTICOID; RISK FACTORS; SOCIAL ENVIRONMENT; SOCIAL ISOLATION; STRESS, PHYSIOLOGICAL; STRESS, PSYCHOLOGICAL;

ANIMALIA; RATTUS;

EID: 76049124790     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0910753106     Document Type: Article

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