Translating Response During Therapy into Ultimate Treatment Outcome: A Personalized 4-Dimensional MRI Tumor Volumetric Regression Approach in Cervical Cancer

International Journal of Radiation Oncology Biology Physics

Volumn 76, Issue 3, 2010, Pages 719-727

  Mayr, Nina A ^a   Wang, Jian Z ^a   Lo, Simon S ^a   Zhang, Dongqing ^a   Grecula, John C ^a   Lu, Lanchun ^a   Montebello, Joseph F ^a   Fowler, Jeffrey M ^a   Yuh, William T C ^a  

^a OHIO STATE UNIVERSITY   (United States)

Author keywords

Cervical cancer; Magnetic resonance imaging; Tumor volume; Tumor volume regression

Indexed keywords

CERVICAL CANCERS; CLINICAL APPLICATION; DISEASE-SPECIFIC SURVIVAL RATES; DISEASE-SPECIFIC SURVIVALS; LOCAL CONTROL; LOCAL FAILURE; OVERALL SURVIVAL; RADIATION THERAPY; REGRESSION CURVE; REGRESSION PARAMETERS; RESIDUAL TUMORS; TREATMENT OUTCOMES; TUMOR REGRESSION; TUMOR RESPONSE; TUMOR VOLUME; TUMOR VOLUMES; VOLUMETRY;

CORRELATION METHODS; DISEASE CONTROL; MAGNETIC RESONANCE; MAGNETIC RESONANCE IMAGING; RADIOTHERAPY; TUMORS;

REGRESSION ANALYSIS;

ADULT; AGED; ARTICLE; CANCER CONTROL; CANCER RADIOTHERAPY; CANCER STAGING; CANCER SURVIVAL; CLINICAL TRIAL; FEMALE; FOLLOW UP; HUMAN; MAJOR CLINICAL STUDY; MINIMAL RESIDUAL DISEASE; NUCLEAR MAGNETIC RESONANCE IMAGING; OUTCOME ASSESSMENT; OVERALL SURVIVAL; PRIORITY JOURNAL; PROGNOSIS; RADIATION DOSE; SURVIVAL TIME; TREATMENT OUTCOME; TUMOR REGRESSION; TUMOR VOLUME; UTERINE CERVIX CANCER;

ADULT; AGED; AGED, 80 AND OVER; AREA UNDER CURVE; FEMALE; FOLLOW-UP STUDIES; HUMANS; MAGNETIC RESONANCE IMAGING; MIDDLE AGED; PROSPECTIVE STUDIES; RADIOTHERAPY DOSAGE; REGRESSION ANALYSIS; REMISSION INDUCTION; TIME FACTORS; TREATMENT OUTCOME; TUMOR BURDEN; UTERINE CERVICAL NEOPLASMS;

EID: 76049115039     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2009.02.036     Document Type: Article

References (26)

1. Eifel P.J., Winter K., Morris M., et al. Pelvic irradiation with concurrent chemotherapy versus pelvic and para-aortic irradiation for high-risk cervical cancer: An update of radiation therapy oncology group trial (RTOG) 90-01. J Clin Oncol 22 (2004) 872-880
2. Kastritis E., Bamias A., Efstathiou E., et al. The outcome of advanced or recurrent non-squamous carcinoma of the uterine cervix after platinum-based combination chemotherapy. Gynecol Oncol 99 (2005) 376-382
3. vanNagell JR Jr., Roddick JW Jr., DM L. The staging of cervical cancer: Inevitable discrepancies between clinical staging and pathologic findings. Am J Obstet Gynecol 1971;110:973-978.
4. Mitchell D., Snyder B., Coakley F., et al. Early invasive cervical cancer: Tumor delineation by magnetic resonance imaging, computed tomography, and clinical examination, verified by pathologic results. J Clin Oncol 24 (2006) 5687-5694
5. Mayr N.A., Yuh W.T.C., Zheng J., et al. Tumor size evaluated by pelvic examination compared with 3-D MR quantitative analysis in the prediction of outcome for cervical cancer. Int J Radiat Oncol Biol Phys 39 (1997) 395-404
6. Hricak H.L.C., Sandles L.G., et al. Invasive cervical carcinoma: Comparison of MR imaging and surgical findings. Radiology 166 (1988) 623-631
7. Subak L., Hricak H., Powell C.B., et al. Cervical carcinoma: Computed tomography and magnetic resonance imaging for preoperative staging. Obstet Gynecol 86 (1995) 43-50
8. Kim S.H., Choi B.I., Lee H.P., et al. Uterine cervical carcinoma: comparison of CT and MR findings. Radiology 175 (1990) 45-51
9. Burghardt E., Hoffman H.M., Ebner F., et al. Magnetic resonance imaging in cervical cancer: A basis for objective classification. Gynecol Oncol 33 (1989) 61-67
10. Hricak H. Cancer of the uterus: The value of MRI pre-and post-irradiation. Int J Rad Oncol Biol Phys 21 (1991) 1089-1094
11. Mayr N.A., Magnotta V.A., Ehrhardt J.C., et al. Usefulness of tumor volumetry by magnetic resonance imaging in assessing response to radiation therapy in carcinoma of the uterine cervix. Int J Radiat Oncol Biol Phys 35 (1996) 915-924
12. Hatano K., Sekiya Y., Araki H., et al. Evaluation of the therapeutic effect of radiotherapy on cervical cancer using magnetic resonance imaging. Int J Radiat Oncol Biol Phys 45 (1999) 693-644
13. Ohara K., Oki A., Tanaka Y.O., et al. Early determination of uterine cervical squamous cell carcinoma radioresponse identifies high- and low-response tumors. Int J Radiat Oncol Biol Phys 64 (2006) 1179-1182
14. Annual report of treatment in gynecologic cancer. Int Fed Gynecol Obstet 20 (1988) 40
15. Eifel P.J., Morris M., Wharton J.T., and Oswald M.J. The influence of tumor size and morphology on the outcome of patients with FIGO stage IB squamous cell carcinoma of the uterine cervix. Int J Radiat Oncol Biol Phys 29 (1994) 9-16
16. Kovalic J.J., Perez C.A., Grigsby P.W., and Lockett M.A. The effect of volume of disease in patients with carcinoma of the uterine cervix. Int J Radiat Oncol Biol Phys 21 (1991) 905-910
17. Hricak H., Powell C.B., Yu K.K., et al. Invasive cervical carcinoma: Role of MR imaging in pretreatment work-up-cost-minimization and diagnosis efficacy. Radiology 198 (1996) 403-409
18. Kim H., Kim W., Lee M., Song E., and Loh J.J. Tumor volume and uterine body invasion assessed by MRI for prediction of outcome in cervical carcinoma treated with concurrent chemotherapy and radiotherapy. Jpn J Clin Oncol 37 (2007) 858-866
19. Kodaira T., Fuwa N., Kamata M., et al. Clinical assessment by MRI for patients with Stage II cervical carcinoma treated by radiation alone in multicenter analysis: Are all patients with Stage II disease suitable candidates for chemotherapy?. Int J Rad Oncol Biol Phys 52 (2002) 627-636
20. Wagenaar H.C.T.J., Postema S., Anastasopoulou A., et al. Tumor diameter and volume assessed by magnetic resonance imaging in the prediction of outcome for invasive cervical cancer. Gynecol Oncol 82 (2001) 474-482
21. Ebner F., Kressel H.Y., Mintz M.C., et al. Tumor recurrence versus fibrosis in the female pelvis: Differentiation with MR imaging at 1.5 T. Radiology 166 (1988) 333-340
22. Mayr N.A., Yuh W.T.C., Taoka T., et al. Serial therapy-induced changes in tumor shape in cervical cancer and their impact on assessing tumor volume and treatment response. AJR Am J Roentgenol 187 (2006) 65-72
23. Hricak H., Quivey J., Campos Z., et al. Carcinoma of the cervix: Predictive value of clinical and magnetic resonance (MR) imaging assessment of prognostic factors. Int J Radiat Oncol Biol Phys 27 (1993) 791-801
24. Vincens E., Balleyguier C., Rey A., et al. Accuracy of magnetic resonance imaging in predicting residual disease in patients treated for stage IB2/II cervical carcinoma with chemoradiation therapy. Cancer 113 (2008) 2158-2165
25. Pötter R., Dimopoulos J., Georg P., et al. Clinical impact of MRI assisted dose volume adaptation and dose escalation in brachytherapy of locally advanced cervix cancer. Radiother Oncol 83 (2007) 148-155
26. Schwarz J.K., Siegel B.A., Dehdashti F., and Grigsby P.W. Association of posttherapy positron emission tomography with tumor response and survival in cervical carcinoma. JAMA 298 (2007) 2289-2295