Detection method and toxicity study of a new disinfection by-product, 2,2,4-trichloro-5-methoxycyclopenta-4-ene-1,3-dione (TCMCD), in chlorinated drinking water

Water Research

Volumn 44, Issue 3, 2010, Pages 974-980

  Shen, Xing ^a,b   Shao, Zhijuan ^a   Xian, Qiming ^a   Zou, Huixian ^a   Gao, Shixiang ^a   Zhang, Jinqi ^a  

^a NANJING UNIVERSITY   (China)

^b Jiangsu Institute of Measurement and Testing Technology   (China)

Author keywords

Detection method; Drinking water; New disinfection by products; TCMCD; Toxicity

Indexed keywords

BYPRODUCTS; DISINFECTION; TOXICITY;

2,2,4-TRICHLORO-5-METHOXYCYCLOPENTA-4-ENE-1,3-DIONE; CHLORINATED DRINKING WATERS; DETECTION METHODS; DISINFECTION BY-PRODUCT; DISINFECTION BYPRODUCTS; DRINKING WATER SAMPLES; JIANGSU PROVINCE; NEW DISINFECTION BY-PRODUCT; ZEBRAFISH;

POTABLE WATER;

2,2, 4 TRICHLORO 5 METHOXYCYCLOPENTA 4 ENE 1,3 DIONE; CHLORINATED DRINKING WATER; DISINFECTANT AGENT; DRINKING WATER; UNCLASSIFIED DRUG;

CHLORINATION; DETECTION METHOD; DISINFECTION; DRINKING WATER; TOXICITY;

ANIMAL EXPERIMENT; ARTICLE; CHEMICAL ANALYSIS; CHEMICAL MUTAGENESIS; CHINA; CONTROLLED STUDY; EMBRYO; EMBRYOTOXICITY; MICRONUCLEUS TEST; NONHUMAN; PERIPHERAL LYMPHOCYTE; PRIORITY JOURNAL; SOLID PHASE EXTRACTION; TOXICITY TESTING; WATER QUALITY; WATER SAMPLING; ZEBRA FISH;

CHINA; JIANGSU;

DANIO RERIO;

EID: 76049110856     PISSN: 00431354     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.watres.2009.10.006     Document Type: Article

References (27)

1. Gao S.Q., and Xie Z.A. The influence of wastewater from the Huaihe River on the quality of tap water in Jinhu city. Jiangsu Health Care 6 (2004) 32-33 (in Chinese)
2. Glofinopoulos S.K., and Nikolaou A.D. Disinfection by-products and volatile organic compounds in the water supply system in Athens, Greece. Journal of Environmental Science and Health, Part A 36 4 (2001) 483-499
3. Gong H.J., You Z., Xian Q.M., Shen X., and Zou H.X. Study on the structure and mutagenicity of a new disinfection byproduct in chlorinated drinking water. Environmental Science and Technology 39 (2005) 7499-7508
4. Feng S.L., Kong Z.M., Wang X.M., Peng P.A., and Zeng E.Y. Assessing the genotoxicity of imidacloprid and RH-5849 in human peripheral blood lymphocytes in vitro with comet assay and cytogenetic tests. Ecotoxicology and Environmental Safety 61 (2005) 239-246
5. Krasner S.W., Weinberg H.S., Richardson S.D., Pastor S.J., Chinn R., Sclimenti M.J., Onstad G.D., and Thruston A.D. Occurrence of a new generation of disinfection byproducts. Environmental Science and Technology 40 23 (2006) 7175-7185
6. Kronberg L., and Vertiainen T. Ames mutagenicity and concentration of the strong mutagen 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone and of its geometric isomer E-2-chloro-3-(dichloromethyl)-4-oxobutenoic acid in chlorine-treated tap waters. Mutant Research 206 (1998) 177-182
7. Le F.T., and Zhang H.B. The circumstance and countermeasure of water quality in the middle section of the Tongyu River (Yancheng section). Jiangsu Water Resources 7 (2007) 31-32 (in Chinese)
8. Li J.F., Li W.H., Jin T.Y., and Ding X.C. Zebrafish and its application in environmental toxicology. Journal of Environmental and Occupational Medicine 22 5 (2005) 460-463
9. Li Y.L., Zhou G.K., and Wang W.H. The practicing and thinking to the protection of raw water resource in the Xiangshui section of the Tongyu River. Jiangsu Water Resources 11 (2007) 39-40 (in Chinese)
10. Liu H., Yao Z.W., Chen Z.B., and Gao Y. The investigation and study on drinking water in rural area, China. Jiangsu Water Resources 10 (2005) 24-25 (in Chinese)
11. Lu J.H., Zou H.X., Yang C.Y., Yu Z.R., and Zhang J.Q. Some problems in the detection of strong mutagen MX formed by chlorinating the aromatic acids and phenolic compounds. Water Research 36 (2002) 970-974
12. Lu J.H., Zou H.X., Yu Z.R., Xu X., and Zhang J.Q. The interference of 2-chloro-5-oxo-3-hexene diacyl chloride (COHC) in the detection of strong mutagen MX. Chemosphere 48 (2002) 29-33
13. Ma J.G., and Xue K.X. A quick and handy method to produce lymphocyte micronucleus slide. Chinese Journal of Cell Biology 11 (1989) 143-145
14. Ma Y.Y., Shen X., Zhang J.Q., Xian Q.M., and Zou H.X. The synthesis and structure confirmation of a new disinfection by-product TCMCD. Environmental Chemistry 26 4 (2007) 495-498 (in Chinese)
15. Majer B.J., Laky B., Knasmuller S., and Kassie F. Use of the micronucleus assay with exfoliated epithelial cells as a biomarker for monitoring individuals at elevated risk of genetic damage and in chemoprevention trials. Mutant Research 489 (2001) 147-172
16. Monica L., Wolfgang G., Jurgen M., and Roland G. Comparison of testing acute toxicity on embryo of zebrafish, Brachydanio rerio and RTG-2 cytotoxicity as possible alternatives to the acute fish test. Chemosphere 30 11 (1995) 2087-2102
17. Plewa M.J., Wagner E.D., Jazwierska P., Richardson S.D., Chen P.H., and McKague A.B. Halonitromethane drinking water disinfection byproducts: chemical characterization and mammalian cell cytotoxicity and genotoxicity. Environmental Science and Technology 38 1 (2004) 62-68
18. Plewa M.J., Wagner E.D., Richardson S.D., Thruston A.D., Woo Y., and McKague A.B. Chemical and biological characterization of newly discovered iodoacid drinking water disinfection byproducts. Environmental Science and Technology 38 18 (2004) 4713-4722
19. Richardson S.D. Disinfection by-products and other emerging contaminants in drinking water. Trends in Analytical Chemistry 22 10 (2003) 666-684
20. Richardson S.D., Ellington J.J., Crumley F.G., Evans J.J., Plewa M.J., Wagner E.D., and McKague A.B. Occurrence of iodoacid DBPs in U.S. chloraminated drinking waters. Environmental Chemistry 46 1 (2006) 542-546 Preprints of Extended Abstracts - ACS National Meeting, American Chemical Society, Division of Environmental Chemistry
21. Richardson S.D., Simmons J.E., and Rice G. Disinfection byproducts: the next generation. Environmental Science and Technology 36 9 (2002) 198A-205A
22. Rook J.J. Formation of haloforms during chlorination of natural waters. Water Treatment Exam 23 (1974) 234-243
23. Schulte C., and Nagel R. Testing acute toxicity in embryo of zebra fish, Brachydanio rerio, as alternative to the acute fish test-preliminary result. ATLA - Alternatives to Laboratory Animals 22 (1994) 12-19
24. Suarez S., Sueiro R.A., and Garrido J. Genotoxicity of the coating lacquer on food cans, bisphenol A diglycidyl ether (BADGE), its hydrolysis products and a chlorohydrin of BADGE. Mutant Research 470 (2000) 221-228
25. Weinberg H. Disinfection byproducts in drinking water: the analytical challenge. Analytical Chemistry 71 23 (1999) 801-808
26. Westerfield M. The Zebra Fish Book: a Guide for the Laboratory Use of Zebra Fish (Brachydanio rerio). third ed. (1993), Eugene, University of Iregon Press, Institute of Neuroscience, USA
27. Xing W.P., Zhao H.K., and Jiang Z.R. Aapplication of micronucleus assay in genetic toxicology. Anhui Journal of Preventive Medicine 8 5 (2002) 317-320 (in Chinese)