Beneficial effects and reversion of vascular lesions by thalidomide in a patient with bleeding portal hypertensive enteropathy

Digestive and Liver Disease

Volumn 42, Issue 3, 2010, Pages 232-233

  Jimenez Saenz, M ^a   Romero Vazquez, J ^a   Caunedo Alvarez, A ^a   Maldonado Perez, B ^a   Gutierrez, J M Herrerias ^a  

^a HOSPITAL UNIVERSITARIO VIRGEN MACARENA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ATROPINE; PROPRANOLOL; THALIDOMIDE;

ADULT; ANEMIA; ANGIODYSPLASIA; ARGON PLASMA COAGULATION; CAPSULE ENDOSCOPY; CASE REPORT; COLONOSCOPY; DRUG WITHDRAWAL; ENTEROPATHY; ERYTHROCYTE CONCENTRATE; ERYTHROCYTE TRANSFUSION; ESOPHAGUS VARICES; FEMALE; GASTROINTESTINAL ENDOSCOPY; HEPATITIS C VIRUS; HUMAN; ILEUM; INTESTINAL BLEEDING; IRON METABOLISM; JEJUNUM; LETTER; LIVER CIRRHOSIS; MELENA; PORTAL HYPERTENSION; PORTAL HYPERTENSIVE ENTEROPATHY; PRIORITY JOURNAL; SINUS BRADYCARDIA; SINUS TACHYCARDIA; VASCULAR LESION;

ANGIODYSPLASIA; ANGIOGENESIS INHIBITORS; COMPASSIONATE USE TRIALS; FEMALE; GASTROINTESTINAL HEMORRHAGE; HUMANS; HYPERTENSION, PORTAL; ILEUM; MIDDLE AGED; PROTEIN-LOSING ENTEROPATHIES; THALIDOMIDE;

EID: 76049106839     PISSN: 15908658     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.dld.2009.06.001     Document Type: Letter

References (5)

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2. Figueiredo P., Almeida N., Lérias C., et al. Effect of portal hypertension in the small bowel: an endoscopic approach. Dig Dis Sci 53 (2008) 2144-2150
3. Fernandez M., Mejias M., Garcia-Pras E., Mendez R., Garcia-Pagan J.C., and Bosch J. Reversal of portal hypertension and hyperdynamic splanchnic circulation by combined vascular endothelial growth factor and platelet-derived growth factor blockade in rats. Hepatology 46 (2007) 1208-1217
4. Abraldes J.G., Iwakiri Y., Loureiro-Silva M., Haq O., Sessa W.C., and Groszmann R.J. Mild increases in portal pressure upregulate vascular endothelial growth factor and endothelial nitric oxide synthase in the intestinal microcirculatory bed, leading to a hyperdynamic state. Am J Physiol Gastrointest Liver Physiol 290 (2006) G980-G987
5. Lopez-Talavera J.C., Cadelina G., Olchowski J., Merrill W., and Groszmann R.J. Thalidomide inhibits tumor necrosis factor alpha, decreases nitric oxide synthesis, and ameliorates the hyperdynamic circulatory syndrome in portal-hypertensive rats. Hepatology 23 (1996) 1616-1621