The effect of stealth liposomes on pharmacokinetics, tissue distribution and anti-tumor activity of oridonin

PDA Journal of Pharmaceutical Science and Technology

Volumn 63, Issue 5, 2009, Pages 409-416

  Wang, Chuanjin ^a   Wei, Yunyang ^a   Yu, Li ^b   Zhang, Liang ^b  

^a NANJING UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b NANJING UNIVERSITY OF CHINESE MEDICINE   (China)

Author keywords

Anti tumor activity; Liposomes; Oridonin; Pharmacokinetics; Tissue distribution

Indexed keywords

DISTEAROYLPHOSPHATIDYLCHOLINE; LIPOSOME; MACROGOL 2000; ORIDONIN; STEALTH LIPOSOME; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER GROWTH; CIRCULATION TIME; CONTROLLED STUDY; DISPERSION; DRUG EFFECT; DRUG INHIBITION; DRUG ISOLATION; DRUG PURITY; FEMALE; FILM; HEART; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MALE; MOUSE; NONHUMAN; RABDOSIA; RETICULOENDOTHELIAL SYSTEM; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SOLID TUMOR; TISSUE DISTRIBUTION; VALIDATION PROCESS;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DITERPENES, KAURANE; DRUG CARRIERS; DRUG SCREENING ASSAYS, ANTITUMOR; FEMALE; LIPOSOMES; LIVER NEOPLASMS, EXPERIMENTAL; MALE; MICE; MONONUCLEAR PHAGOCYTE SYSTEM; MYOCARDIUM; PHOSPHATIDYLETHANOLAMINES; POLYETHYLENE GLYCOLS; RABDOSIA; TISSUE DISTRIBUTION;

EID: 76049094467     PISSN: 10797440     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (14)

1. Gref, R.; Minamitake, Y.; Peracchia, M. T.; Trubetskoy, V.; Torchilin, V.; Langer, R. Biodegradable longcirculating polymeric nanospheres. Science 1994, 263 (5153), 1600-1603.
2. Woodle, M. C.; Lasic, D. D. Sterically stabilized liposomes. Biochim. Biophys. Acta 1992, 1113 (2), 171-199.
3. Metselaar, J. M. Liposomal Targeting of Glucocorticoids: A Novel Treatment Approach for Inflammatory Disorders. PhD Thesis, Utrecht University, Utrecht, Netherlands, 2003.
4. Allen, T. M. Long-circulating (sterically stabilized) liposomes for targeted drug delivery. Trends Pharmacol. Sci 1994, 15 (7), 215-220.
5. Litzinger, D. C.; Buiting, A. M.; van Rooijen, N.; Huang, L. Effect of liposome size on the circulation time and intraorgan distribution of amphipathic poly(ethylene glycol)-containing liposomes. Biochim. Biophys. Acta 1994, 1190 (1), 99-107.
6. Liu, J.; Liang, J. Y.; Xie, T. Development of Rabdosia Rubescens [Hemsl] Hara. Strait Pharmaceutical Journal 2004, 16 (2), 1-7.
7. China Pharmacopoeia Committee. Pharmacopoeia of the People's Republic of China. Chemical Industry Press; Beijing, China, 1978; p 186.
8. Han, Q. B.; Li, M. L.; Li, S. H.; Mou, Y. K.; Lin, Z. W.; Sun, H. D. Ent-kaurane diterpenoids from Isodon rubescens var. Lushanensis. Chem. Pharm. Bull. (Tokyo) 2003, 51(7), 790-793.
9. Zhang, J. X.; Han, Q. B.; Zhao, A. H.; Sun, H. D. Diterpenoids from Isodon japonica. Fitoterapia 2003, 74 (5), 435-438.
10. Ikezoe, T.; Chen, S. S.; Tong, X. J.; Heber, D.; Taquchi, H.; Koeffler, H. P. Oridonin induces growth inhibition and apoptosis of a variety of human cancer cells. Int. J. Oncol 2003, 23 (4), 1187-1189.
11. Wang, C. J.; Wei, Y. Y.; Lu J, Du, Y. Y. Isolation of oridonin from Rabdosia rubescens Hemsl by preparative high performance liquid chromatography. Fine Chemicals 2007, 24 (7), 662-666.
12. Wei, N. N.; Wen, H.; Lu, B. Tissue distribution and pharmacokinetics of liposomal albendazole in mice. J. Huaxi. Pharmacy 2002, 17 (2), 95-97.
13. Zheng, H. H.; Zhou, X. M.; Ma, E. L.; Cao, Y. L.; Dai, Y. Anti-tumor activity of the compound recipe Radix sophorae flavescentis for injection in vivo and in vitro. Asian Journal of Traditional Medicines 2007, 2 (1), 19-22.
14. Fujita, E.; Nagao, Y.; Node, M. Diterpenoids of Isodon and Teucrium plants. Heterocycles 1976, 5 (1), 793-838.