Transient behavior and stability in miniaturized multiphase packed bed reactors

Industrial and Engineering Chemistry Research

Volumn 49, Issue 3, 2010, Pages 1033-1040

  Márquez, Nathalie ^a   Castaño, Pedro ^a   Moulijn, Jacob A ^a   Makkee, Michiel ^a   Kreutzer, Michiel T ^a  

^a DELFT UNIVERSITY OF TECHNOLOGY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

HIGH-THROUGHPUT; HYDRODYNAMIC BEHAVIOR; HYDRODYNAMIC RESPONSE; INTERNAL DIAMETERS; KINETIC EXPERIMENT; LIMITING FACTORS; LIQUID SATURATION; MICRO-REACTOR; NONPOROUS PARTICLES; OPERATING CONDITION; PACKED BED REACTOR; PRE-WETTING; REMARKABLE IMPACT; RESIDENCE TIME; SHARP CONTRAST; STABLE OPERATION; START-UP PROCEDURE; STEADY STATE; TRANSIENT BEHAVIOR;

CHEMICAL REACTORS; FLUID DYNAMICS; HYDRODYNAMICS; LIQUIDS;

PACKED BEDS;

EID: 76049089063     PISSN: 08885885     EISSN: None     Source Type: Journal    
DOI: 10.1021/ie900694r     Document Type: Conference Paper

References (30)

1. Mills, P. L.; Nicole, J. F. Multiple automated reactor systems (MARS). 1. A novel reactor system for detailed testing of gas-phase heterogeneous oxidation catalysts. Ind. Eng. Chem. Res. 2005, 44 (16), 6435-6452.
2. Perez-Ramirez, J.; Berger, R. J.; Mul, G.; Kapteijn, F.; Moulijn, J. A. The six-flow reactor technology - A review on fast catalyst screening and kinetic studies. Catal. Today 2000, 60 (1-2), 93-109.
3. Moulijn, J. A.; Perez-Ramirez, J.; Berger, R. J.; Hamminga, G.; Mul, G.; Kapteijn, F. High-throughput experimentation in catalyst testing and in kinetic studies for heterogeneous catalysis. Catal. Today 2003, 81 (3), 457- 471.
4. Corma, A.; Serra, J. M. Heterogeneous combinatorial catalysis applied to oil refining, petrochemistry and fine chemistry. Catal. Today 2005, 107-08, 3-11.
5. Morra, G.; Farrusseng, D.; Guillon, E.; Morin, S.; Bouchy, C.; Duchene, P.; Mirodatos, C. Deactivation handling in a high-throughput kinetic study of o-xylene hydrogenation. Catal. Today 2008, 137, 71-79.
6. Klein, J.; Stichert, W.; Strehlau, W.; Brenner, A.; Demuth, D.; Schunk, S. A.; Hibst, H.; Storck, S. Accelerating lead discovery via advanced screening methodologies. Catal. Today 2003, 81 (3), 329-335.
7. Maxwell, I. E.; van den Brink, P.; Downing, R. S.; Sijpkes, A. H.; Gomez, S.; Maschmeyer, T. High-throughput technologies to enhance innovation in catalysis. Top. Catal. 2003, 24 (1-4), 125-135.
8. Wada, Y.; Schmidt, M. A.; Jensen, K. F. Flow distribution and ozonolysis in gas-liquid multichannel microreactors. Ind. Eng. Chem. Res. 2006, 45 (24), 8036-8042.
9. Van Steijn, V.; Makkee, M.; Kleijn, C. R.; Kreutzer, M. T.; Guenther, A. In Multiphase flow in a forest of micropillars. 1st European Conference on Microfluidics, Bologna, Italy, Dec 10-12, 2008.
10. de Santos, J. M.; Melli, T. R.; Scriven, L. E. Mechanics of gas-liquid flow in packed bed contactors. Annu. ReV. Fluid Mech. 1991, 23, 233-260.
11. Lenormand, R.; Touboul, E.; Zarcone, C. Numerical models and experiments on immiscible displacements in porous media. J. Fluid Mech. 1988, 189, 165-187.
12. Dullien, F. A. L. Capillary effects and multiphase flow in porous media. J. Porous Media 1998, 1 (1), 1-29.
13. Hassanizadeh, S. M.; Gray, W. G. Toward an improved description of the physics of two-phase flow. Adv. Water Resour. 1993, 16 (1), 53-67.
14. Muccino, J. C.; Gray, W. G.; Ferrand, L. A. Toward an improved understanding of multiphase flow in porous media. Rev. Geophys. 1998, 36 (3), 401-422.
15. Bravo, M. C.; Araujo, M.; Lago, M. E. Pore network modeling of two-phase flow in a liquid-(disconnected) gas system. Physica A 2007, 375 (1), 1-17.
16. Kan, K. M.; Greenfield, P. F. Multiple hydrodynamic states in cocurrent two-phase downflow through packed-beds. Ind. Eng. Chem. Process Des. Dev. 1978, 17 (4), 482-485.
17. Levec, J.; Saez, A. E.; Carbonell, R. G. The Hydrodynamics of Trickling Flow in Packed-Beds 0.2. Experimental-Observations. AIChE J. 1986, 32 (3), 369-380.
18. Wang, R.; Mao, Z. S.; Chen, J. Y. Experimental and theoretical studies of pressure drop hysteresis in trickle bed reactors. Chem. Eng. Sci. 1995, 50 (14), 2321-2328.
19. Gunjal, P. R.; Kashid, M. N.; Ranade, V. V.; Chaudhari, R. V. Hydrodynamics of trickle-bed reactors: Experiments and CFD modeling. Ind. Eng. Chem. Res. 2005, 44 (16), 6278-6294.
20. Saroha, A. K.; Nandi, I. Pressure drop hysteresis in trickle bed reactors. Chem. Eng. Sci. 2008, 63 (12), 3114-3119.
21. Maiti, R.; Khanna, R.; Nigam, K. D. P. Hysteresis in trickle-bed reactors: A review. Ind. Eng. Chem. Res. 2006, 45 (15), CP5-5198.
22. Van der Merwe, W.; Nicol, W. Trickle flow hydrodynamic multiplicity: Experimental observations and pore-scale capillary mechanism. Chem. Eng. Sci. 2009, 64 (6), 1267-1284.
23. Ravindra, P. V.; Rao, D. P.; Rao, M. S. Liquid flow texture in trickle-bed reactors: An experimental study. Ind. Eng. Chem. Res. 1997, 36 (12), 5133-5145.
24. Van der Merwe, W.; Nicol, W.; de Beer, F. Trickle flow distribution and stability by X-ray radiography. Chem. Eng. J. 2007, 132 (1-3), 47- 59.
25. Stanek, V.; Svoboda, P.; Jiricny, V. Experimental observation of pressure and holdup overshoot following a sudden increase of liquid flow. Ind. Eng. Chem. Res. 2001, 40 (14), 3230-3236.
26. Tabeling, P. Introduction to Microfluidics; Oxford University Press: New York, 2005.
27. Martin, M.; Blu, G.; Eon, C.; Guiochon, G. Use of syringe-type pumps in liquid chromatography in order to achieve a constant flow-rate. J. Chromatogr. 1975, 112 (OCT29), 399-414.
28. Stone, H. A.; Stroock, A. D.; Ajdari, A. Engineering flows in small devices: Microfluidics toward a lab-on-a-chip. Annu. Rev. Fluid Mech. 2004, 36, 381-411.
29. Márquez, N.; Castaño, P.; Makkee, M.; Moulijn, J. A.; Kreutzer, M. T. Dispersion and holdup in multiphase packed bed microreactors. Chem. Eng. Technol. 2008, 31 (8), 1130-1139.
30. Van Herk, D.; Castaño, P.; Makkee, M.; Moulijn, J. A.; Kreutzer, M. T. Catalyst testing in a multiple-parallel, gas-liquid, powder-packed bed microreactor. Appl. Catal. A: Gen. 2009, 365 (2), 199-206.