Synthesis and preliminary evaluation of antidiabetic activity of 4-(3-(4-bromophenyl)-3-oxo-l-arylpropyIamino)-N-(5-methylisoxazol-3-yl) benzenesuIfonamide

Yaoxue Xuebao

Volumn 44, Issue 11, 2009, Pages 1244-1251

  Zhang, Ying Xia ^a   Yan, Ju Fang ^b   Fan, Li ^a   Zhang, Wei Yu ^b   Zhou, Zu Wen ^a   Chen, Xin ^b   Su, Xiao Yan ^a   Tang, Xue Mei ^a   Yang, Da Cheng ^a  

^a SOUTHWEST UNIVERSITY   (China)

^b Chengdu Diao Pharmaceutical Group Co Ltd   (China)

Author keywords

amino ketone; A glucosidase; PPRE; PTP1B; Sulfamethoxazole

Indexed keywords

4 (3 (4 BROMOPHENYL) 3 OXO 1 ARYLPROPYLAMINO) N (5 METHYLISOXAZOL 3 YL)BENZENESULFONAMIDE; ACETOPHENONE DERIVATIVE; ALCOHOL; ALDEHYDE; ALPHA GLUCOSIDASE; BETA AMINO ACID; HYDROCHLORIC ACID; IODINE; KETONE DERIVATIVE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; PIOGLITAZONE; PROTEIN TYROSINE PHOSPHATASE 1B; SULFAMETHOXAZOLE; SULFONAMIDE; UNCLASSIFIED DRUG;

ANTIDIABETIC ACTIVITY; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CATALYSIS; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DRUG ACTIVITY; DRUG DESIGN; DRUG INHIBITION; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; MANNICH REACTION; MASS SPECTROMETRY; PROTON NUCLEAR MAGNETIC RESONANCE;

ALPHA-GLUCOSIDASES; HUMANS; HYPOGLYCEMIC AGENTS; MOLECULAR STRUCTURE; OXAZOLES; PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 1; RESPONSE ELEMENTS; STRUCTURE-ACTIVITY RELATIONSHIP; SULFONAMIDES; THIAZOLIDINEDIONES;

EID: 76049088794     PISSN: 05134870     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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