Dual-contrast dynamic MRI-DOT for small animal imaging

Technology in Cancer Research and Treatment

Volumn 9, Issue 1, 2010, Pages 61-69

  Thayer, David ^a   Unlu, Mehmet Burcin ^a,b   Lin, Yuting ^a   Yan, Kevin ^a   Nalcioglu, Orhan ^a   Gulsen, Gultekin ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b BOGAZICI UNIVERSITY   (Turkey)

Author keywords

Animal imaging; Cancer; Diffuse optical tomography; DOT; Dynamic contrast enhanced imaging; Gadolinium; ICG; MRI; Multimodality; Reconstruction

Indexed keywords

GADOLINIUM PENTETATE; INDOCYANINE GREEN;

ANIMAL MODEL; ARTICLE; BREAST CANCER; CONTRAST ENHANCEMENT; CONTROLLED STUDY; DYNAMICS; KINETICS; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; OPTICAL TOMOGRAPHY; RADIATION ABSORPTION; RAT; TUMOR VOLUME;

EID: 76049088323     PISSN: 15330346     EISSN: None     Source Type: Journal    
DOI: 10.1177/153303461000900107     Document Type: Article

References (23)

1. Eby, P. R., Lehman, C. D. Magnetic resonance imaging-guided breast interventions, Top. Magn Reson Imaging 19, 151-162 (2008).
2. Turnbull, L. W. Dynamic contrast-enhanced MRI in the diagnosis and management of breast cancer. NMR Biomed 22, 28-39 (2009).
3. Su, M. Y., Muhler, A., Lao, X., Nalcioglu, O. Tumor characterization with dynamic contrast-enhanced MRI using MR contrast agents of various molecular weights. Magn Reson Med 39, 259-269 (1998).
4. Yu, H., Su, M. Y., Wang, Z., Nalcioglu, O. A longitudinal study of radiation-induced changes in tumor vasculature by contrast-enhanced magnetic resonance imaging. Radiat Res 158, 152-158 (2002).
5. Su, M. Y., Jao, J. C., Nalcioglu, O. Measurement of vascular volume fraction and blood-tissue permeability constants with a pharmaco-kinetic model: studies in rat muscle tumors with dynamic Gd-DTPA enhanced MRI. Magn Reson Med 32, 714-724 (1994).
6. Su, M. Y., Muhler, A., Lao, X., Nalcioglu, O. Tumor characterization with dynamic contrast-enhanced MRI using MR contrast agents of various molecular weights. Magn Reson Med 39, 259-269 (1998).
7. Su, M. Y., Najafi, A. A., Nalcioglu, O. Regional comparison of tumor vascularity and permeability parameters measured by albumin-Gd-DTPA and Gd-DTPA. Magn Reson Med 34, 402-411 (1995).
8. FoxOX, I. J., Brooker, L. G., Heseltine, D. W., Essex, H. E., Wood, E. H., A tricarbocyanine dye for continuous recording of dilution curves in whole blood independent of variations in blood oxygen saturation. Proc Staff Meet Mayo Clin 32, 478-484 (1957).
9. Landsman, M. L., Kwant, G. G., Mook, A., Zijlstra, W. G. Light-absorbing properties, stability, and spectral stabilization of indocyanine green. J Appl Physiol 40, 575-583 (1976).
10. Cuccia, D. J., Bevilacqua, F., Durkin, A. J., Merritt, S., Tromberg, B. J., Gulsen, G., Yu, H., Wang, J., Nalcioglu, O. In vivo quantification of optical contrast agent dynamics in rat tumors by use of diffuse optical spectroscopy with magnetic resonance imaging coregistration. Appl Opt 42, 2940-2950 (2003).
11. Hillman, E. M., Moore, A. All-optical anatomical co-registration for molecular imaging of small animals using dynamic contrast. Nat Photonics 1, 526-530 (2007).
12. Ntziachristos, V., Yodh, A. G., Schnall, M., Chance, B. Concurrent MRI and diffuse optical tomography of breast after indocyanine green enhancement. Proc Natl Acad Sci US A 97, 2767-2772 (2000).
13. Konecky, S. D., Panasyuk, G. Y., Lee, K, Markel, V., Yodh, A. G., Schotland, J. C. Imaging complex structures with diffuse light. Opt Express 16, 5048-5060 (2008).
14. Ntziachristos, V., Chance, B. Probing physiology and molecular function using optical imaging: applications to breast cancer. Breast Cancer Res 3, 41-46 (2001).
15. Van de Ven, S. M., Elias, S. G., van den Bosch, M. A., Luijten, P., Mali, W. P. Optical imaging of the breast. Cancer Imaging 8, 206-215 (2008).
16. Luker, G. D., Luker, K. E. Optical imaging: current applications and future directions. J Nucl Med 49, 1-4 (2008).
17. Intes, X., Ripoll, J., Chen, Y., Nioka, S., Yodh, A. G., Chance, B. In vivo continuous-wave optical breast imaging enhanced with Indocyanine Green. Med Phys 30, 1039-1047 (2003).
18. Alacam, B., Yazici, B., Intes, X., Nioka, S., Chance, B. Pharmaco-kinetic-rate images of indocyanine green for breast tumors using near-infrared optical methods. Phys Med Biol 53, 837-859 (2008).
19. Merritt, S., Bevilacqua, F., Durkin, A. J., Cuccia, D. J., Lanning, R., Tromberg, B. J., Gulsen, G., Yu, H., Wang, J., Nalcioglu, O. Coregistration of diffuse optical spectroscopy and magnetic resonance imaging in a rat tumor model. Appl Opt 42, 2951-2959 (2003).
20. Hilf, R., Michel, I., Bell, C., Freeman, J. J., Borman, A. Biochemical and Morphologic Properties of a New Lactating Mammary Tumor Line in the Rat. Cancer Res 25, 286-299 (1965).
21. Gulsen, G., Xiong, B., Birgul, O., Nalcioglu, O. Design and implementation of a multifrequency near-infrared diffuse optical tomography system. J Biomed Opt 11, 014020 (2006).
22. Gulsen, G., Birgul, O., Unlu, M. B., Shafiiha, R., Nalcioglu, O. Combined diffuse optical tomography (DOT) and MRI system for cancer imaging in small animals. Technol Cancer Res Treat 5, 351-363 (2006).
23. Unlu, M. B., Lin, Y., Gulsen, G. Dynamic contrast-enhanced diffuse optical tomography (DCE-DOT): experimental validation with a dynamic phantom. Phys Med Biol 54, 6739-6755 (2009).