Prediction of prion protein genotype and association of this genotype with lamb performance traits of Suffolk sheep

Journal of Animal Science

Volumn 88, Issue 2, 2010, Pages 428-434

  Sawalha, R M ^a   Villanueva, B ^a,b   Brotherstone, S ^c   Rogers, P L ^d   Lewis, R M ^d  

^a SCOTTISH AGRICULTURAL COLLEGE   (United Kingdom)

^b INIA   (Spain)

^c UNIVERSITY OF EDINBURGH   (United Kingdom)

^d VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY   (United States)

Author keywords

Gene association; Genotype prediction; Prion protein; Scrapie; Sheep

Indexed keywords

ALLELE; ANIMAL; ANIMAL DISEASE; ARTICLE; FEMALE; GENE; GENETIC ASSOCIATION; GENETIC PREDISPOSITION; GENETICS; GENOTYPE; GROWTH, DEVELOPMENT AND AGING; MALE; NEWBORN; PATHOPHYSIOLOGY; PHENOTYPE; PRION; SCRAPIE; SHEEP;

ALLELES; ANIMALS; ANIMALS, NEWBORN; FEMALE; GENES; GENETIC ASSOCIATION STUDIES; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; MALE; PHENOTYPE; PRIONS; SCRAPIE; SHEEP;

ANIMALIA; OVIS ARIES;

EID: 75949105908     PISSN: 00218812     EISSN: 15253163     Source Type: Journal    
DOI: 10.2527/jas.2009-2009     Document Type: Article

References (30)

1. Alexander, B. M., R. H. Stobart, W. C. Russell, K. I. O'Rourke, G. S. Lewis, J. R. Logan, J. V. Duncan, and G. E. Moss. 2005. The incidence of genotypes at codon 171 of the prion protein gene (PRNP) in five breeds of sheep and production traits of ewes associated with those genotypes. J. Anim. Sci. 83:455-459.
2. Brandsma, J. H., L. L. G. Janss, and A. H. Visscher. 2004. Association between PrP genotypes and littersize and 135 days weight in Texel sheep. Livest. Prod. Sci. 85:59-64.
3. Brandsma, J. H., L. L. G. Janss, and A. H. Visscher. 2005. Association between PrP genotypes and performance traits in an experimental Dutch Texel herd. Livest. Prod. Sci. 95:89-94.
4. Casellas, J., G. Caja, R. Bach, O. Francino, and J. Piedrafita. 2007. Association analyses between the prion protein locus and reproductive and lamb weight traits in Ripollesa sheep. J. Anim. Sci.85:592-597.
5. Dawson, M., and V. Del Rio Vilas. 2008. Control of classical scrapie in Great Britain. In Pract. 30:330-333.
6. De Vries, F., N. Borchers, H. Hamann, C. Drögemüller, S. Reinecke, W. Lüpping, and O. Distl. 2004. Associations between the prion protein genotype and performance traits of meat breeds of sheep. Vet. Rec. 155:140-143.
7. De Vries, F., H. Hamann, C. Drögemüller, M. Ganter, and O. Distl. 2005. Analysis of associations between the prion protein genotypes and production traits in East Friesian milk sheep. J. Dairy Sci. 88:392-398.
8. Eglin, R. D., R. Warner, S. Gubbins, S. K. Sivam, and M. Dawson. 2005. Frequencies of PrP genotypes in 38 breeds of sheep sampled in the National Scrapie Plan for Great Britain. Vet. Rec.156:433-437.
9. Fogarty, N. M. 1995. Genetic parameters for live weight, fat and muscle measurements, wool production and reproduction in sheep: A review. Anim. Breed. Abstr. 63:101-143.
10. Gilmour, A. R., B. J. Gogel, B. R. Cullis, and R. Thompson. 2006. ASReml User Guide Release 2.0. VSN Int. Ltd., Hemel Hempstead, UK.
11. Goldmann, W., T. Martin, J. Foster, S. Hughes, G. Smith, K. Hughes, M. Dawson, and N. Hunter. 1996. Novel polymorphisms in the caprine Prp gene: A codon 142 mutation associated with scrapie incubation period. J. Gen. Virol. 77:2885-2891.
12. Hunter, N., J. D. Foster, W. Goldmann, M. J. Stear, J. Hope, and C. Bostock. 1996. Natural scrapie in a closed flock of Cheviot sheep occurs only in specific PrP genotypes. Arch. Virol. 141:809-824.
13. Hunter, N., L. Moore, B. D. Hosie, W. S. Dingwall, and A. Greig. 1997. Association between natural scrapie and PrP genotype in a flock of Suffolk sheep in Scotland. Vet. Rec. 140:59-63.
14. Jones, H. E., R. M. Lewis, M. J. Young, and G. Simm. 2004. Genetic parameters for carcass composition and muscularity in sheep measured by x-ray computer tomography, ultrasound and dissection. Livest. Prod. Sci. 90:167-179.
15. Kerr, R. J., and B. P. Kinghorn. 1996. An efficient algorithm for segregation analysis in large populations. J. Anim. Breed. Genet. 113:457-469.
16. Kinghorn, B. P. 1997. An index of information content for genotype probabilities derived from segregation analysis. Genetics 145:479-483.
17. Lewis, R. M., and P. R. Beatson. 1999. Choosing maternal-effect models to estimate (co)variances for live and fleece weight in New Zealand Coopworth sheep. Livest. Prod. Sci.58:137-150.
18. Lewis, R. M., G. C. Emmans, W. S. Dingwall, and G. Simm. 2002. A description of the growth of sheep and its genetic analysis. Anim. Sci. 74:51-62.
19. Moore, R. C., K. Boulton, and S. C. Bishop. 2009. Associations of PrP genotype with lamb production traits in three commercial breeds of British hill sheep. Animal 3:336-346.
20. Mousa, E., L. D. van Vleck, and K. A. Leymaster. 1999. Genetic parameters for growth traits for a composite terminal sire breed of sheep. J. Anim. Sci. 77:1659-1665.
21. Notter, D. R. 1998. Genetic parameters for growth traits in Suffolk and Polypay sheep. Livest. Prod. Sci. 55:205-213.
22. Roden, J. A., B. G. Merrell, W. A. Murray, and W. Haresign. 2003. Genetic analysis of live weight and ultrasonic fat and muscle traits in a hill sheep flock undergoing breed improvement utilizing an embryo transfer programme. Anim. Sci. 76:367-373.
23. Safari, E., N. M. Fogarty, and A. R. Gilmour. 2005. A review of genetic parameter estimates for wool, growth, meat and reproduction traits in sheep. Livest. Prod. Sci. 92:271-289.
24. Sawalha, R. M., S. Brotherstone, J. Conington, and B. Villanueva. 2007a. Lambs with scrapie susceptible genotypes have higher postnatal survival. PLoS ONE 2:e1236. doi:10.1371/journal. pone.0001236
25. Sawalha, R. M., S. Brotherstone, W. Y. N. Man, J. Conington, L. Bünger, G. Simm, and B. Villanueva. 2007b. Associations of polymorphisms of the ovine prion protein gene with growth, carcass, and computerized tomography traits in Scottish Blackface lambs. J. Anim. Sci. 85:632-640.
26. Simm, G., and W. Dingwall. 1989. Selection indices for lean meat production in sheep. Livest. Prod. Sci. 21:223-233.
27. Simm, G., R. M. Lewis, B. Grundy, and W. Dingwall. 2002. Responses to selection for lean growth in sheep. Anim. Sci. 74:39-50.
28. Sweeney, T., and J. P. Hanrahan. 2008. The evidence of associations between prion protein genotype and production, reproduction, and health traits in sheep. Vet. Res. 39:28.
29. Tongue, S. C., D. U. Pfeiffer, L. Heasman, H. Simmons, and S. J. Ryder. 2006. PrP genotype and lamb birth weight in a scrapiefree environment: Is there an association? Livest. Sci. 105:120-128.
30. Woolhouse, M. E. J., P. Coen, L. Matthews, J. D. Foster, J. M. Elsen, R. M. Lewis, D. T. Haydon, and N. Hunter. 2001. A centuries-long epidemic of scrapie in British sheep? Trends Microbiol. 9:67-70.