Influence of water-soluble flavonoids, quercetin-5′-sulfonic acid sodium salt and morin-5′-sulfonic acid sodium salt, on antioxidant parameters in the subacute cadmium intoxication mouse model

Experimental and Toxicologic Pathology

Volumn 62, Issue 2, 2010, Pages 105-108

  Chlebda, Ewa ^a   Magdalan, Jan ^a   Merwid Lad, Anna ^a   Trocha, Małgorzata ^a   Kopacz, Maria ^b   Kuźniar, Anna ^b   Nowak, Dorota ^b   Szelag, Adam ^a  

^a WROCLAW MEDICAL UNIVERSITY   (Poland)

^b RZESZOW UNIVERSITY OF TECHNOLOGY   (Poland)

Author keywords

Antioxidants; Cadmium intoxication; Flavonoids; GSH; Morin; NaMSA; NaQSA; Quercetin; SOD

Indexed keywords

ANTIOXIDANT; CADMIUM; FLAVONOID; GLUTATHIONE; MORIN; MORIN 5' SULFONIC ACID SODIUM SALT; QUERCETIN 5' SULFONIC ACID SODIUM SALT; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CADMIUM POISONING; CONTROLLED STUDY; LIVER; MALE; MOUSE; NONHUMAN;

ANIMALS; ANTIOXIDANTS; CADMIUM POISONING; FLAVONOIDS; GLUTATHIONE; LIPID PEROXIDATION; LIVER; MALE; MICE; MICE, INBRED BALB C; OXIDATIVE STRESS; QUERCETIN; SUPEROXIDE DISMUTASE;

EID: 75949104747     PISSN: 09402993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.etp.2009.02.118     Document Type: Article

References (17)

1. Amalia P.M., Possa M.N., Augusto M.C., and Francisca L.S. Quercetin prevents oxidative stress in cirrhosic rats. Dig Dis Sci 52 (2007) 2616-2621
2. Eybl V., Kotyzova D., and Bludovska M. The effect of curcumin on cadmium-induced oxidative damage and trace elements in the liver of rats and mice. Toxicol Lett 151 (2004) 79-85
3. Fang Y.Z., Yang S., and Wu G. Free radicals, antioxidants, and nutrition. Nutrition 18 (2002) 872-897
4. Kopacz M., and Kuźniar A. Complexes of cadmium(II), mercury(II) and lead(II) with quercetin-5′-sulfonic acid (QSA). Pol J Chem 77 (2003) 1777-1786
5. Król W., Dworniczak S., Pietsz G., Czuba Z.P., Kunicka M., Kopacz M., et al. Synthesis and tumoricidal activity evaluation of new morin and quercetin sulfonic derivatives. Acta Pol Pharm 59 (2002) 77-79
6. Magdalan J., Szela{ogonek}g A., Kopacz M., Kuźniar A., Nowak D., Kowalski P., et al. Quercetin-5′-sulfonic acid sodium salt and morin-5′-sulfonic acid sodium salt as antidotes in the treatment of acute inorganic mercury poisoning - experimental studies. Adv Clin Exp Med 15 (2006) 581-587
7. Magdalan J., Szela{ogonek}g A., Kopacz M., Kuźniar A., Nowak D., Kowalski P., et al. Morin-5′-sulfonic acid sodium salt as an antidote in the treatment of acute chromium poisoning in rats. Adv Clin Exp Med 15 (2006) 767-776
8. Magdalan J., Szela{ogonek}g A., Chlebda E., Merwid-La{ogonek}d A., Trocha M., Kopacz M., et al. Quercetin-5′-sulfonic acid sodium salt and morin-5′-sulfonic acid sodium salt as antidotes in the subacute cadmium intoxication in mice. Pharmacol Rep 59 Suppl. 1 (2007) 210-216
9. Meyers K.J., Rudolf J.L., and Mitchell A.E. Influence of dietary quercetin on glutathione redox status in mice. J Agric Food Chem 56 (2008) 830-836
10. Molina M.F., Sanchez-Reus I., Iglesias I., and Benedi J. Quercetin, a flavonoid antioxidant, prevents and protects against ethanol-induced oxidative stress in mouse liver. Biol Pharm Bull 6 (2003) 1398-1402
11. Morales A.I., Vicente-Sanchez C., Sandoval J.M., Mayoral P., Arevalo M.A., Fernandez-Tagarro M., et al. Protective effect of quercetin on experimental chronic cadmium nephrotoxicity in rats is based on its antioxidant properties. Food Chem Toxicol 44 (2006) 2092-2100
12. Noor R., Mittal S., and Iqbal J. Superoxide dismutase - applications and relevance to human diseases. Med Sci Monit 8 (2002) RA210-RA215
13. Parihar V.K., Prabhakar K.R., Veerapur V.P., Priyadarsini K.I., Unnikrishan M.K., and Rao C.M. Anticlastogenic activity of morin against whole body gamma irradiation in Swiss albino mice. Eur J Pharmacol 557 (2007) 58-65
14. Ramana B.V., Kumar V.V., Krishna P.N., Kumar C.S., Reddy P.U., and Raju T.N. Effect of quercetin on galactose-induced hyperglycaemic oxidative stress in hepatic and neuronal tissues of Winststar. Acta Diabetol 43 (2006) 135-141
15. Stohs S.J., and Bagchi D. Oxidative mechanisms in the toxicity of metal ions. Free Radic Biol Med 18 (1995) 321-323
16. Szela{ogonek}g A., Magdalan J., Kopacz M., Kuźniar A., Kowalski P., and Pieśniewska M. Assessment of efficacy of quercetin-5′-sulfonic acid sodium salt in the treatment of acute chromium poisoning: experimental studies. Pol J Pharmacol 55 (2003) 1097-1103
17. Wu G., Fang Y.Z., Yang S., Lupton J.R., and Turner N.D. Glutathione metabolism and its implications for health. J Nutr 134 (2004) 489-492