Photoacoustic NO detection for asthma diagnostics

Progress in Biomedical Optics and Imaging - Proceedings of SPIE

Volumn 7371, Issue , 2009, Pages

  Germer, Markus ^a   Wolff, Marcus ^a   Harde, Hermann ^b  

^a HAMBURG UNIVERSITY OF APPLIED SCIENCES   (Germany)

^b HELMUT SCHMIDT UNIVERSITY   (Germany)

Author keywords

Asthma; Nitric oxide; Photoacoustic; QCL

Indexed keywords

AIRWAY INFLAMMATION; ASTHMA; BREATH ANALYSIS; DETECTION SENSITIVITY; DIAGNOSTIC TOOLS; HUMAN BREATH; NEW SYSTEM; PHOTOACOUSTIC; PHOTOACOUSTIC DETECTION; PULSED QUANTUM CASCADE; QCL; SINGLE MODE EMISSION;

INSTRUMENTS; NITRIC OXIDE; PULSED LASER APPLICATIONS; PULSED LASERS; QUANTUM CASCADE LASERS;

DISEASES;

EID: 75849133186     PISSN: 16057422     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1117/12.831774     Document Type: Conference Paper

References (17)

1. Bhagat, K. and Vallance, P., "Nitric oxide 9 years on," J. R. Soc. Med. 89, 667-673 (1996).
2. Nathan, C. and Xie, Q.W., "Nitric oxide synthases: roles, tolls and controls," Cell 78, 915-918 (1994).
3. Kobzik, L., Bredt, C., Lowenstein, C.J., Drazen, J., Gaston, B., Sugarbaker, D. and Stamler, J.S., "Nitric oxide synthase in human and rat lung: immunocytochemical and histochemical localization," Am. J. Respir. Cell Mol. Biol. 9, 371-377 (1993)
4. Gustafsson, L.E., Leone, A.M., Persson, M.G., Wiklund, N.P. and Moncada, S., "Endogenous nitric oxide is present in the exhaled air of rabbits, guinea pigs and humans," Biochem. Biophys. Res. Commun. 181, 852-857 (1991).
5. Alving, K., Weitzberg, E. and Lundberg, J.M., "Increased amount of nitric oxide in exhaled air of asthmatics," Eur. Respir. J. 6, 1368-1370 (1993).
6. Smith, A.D., Cowan, J.O., Filsell, S. et al., "Diagnosing asthma. Comparisons between exhaled nitric oxide measurements and conventional tests," Am. J. Respir. Crit. Care Med. 169, 473-478 (2004).
7. Zacharasiewicz, A., Wilson, N. and Lex, C., et al., "Clinical use of non-invasive measurements of airway inflammation in steroid reduction in children," Am. J. Respir. Crit. Care Med. 171, 1077-1082 (2005).
8. Smith, A.D., Cowan, J.O., Brassett, K.P., Herbison, G.P. and Taylor, D.R., "Use of exhaled nitric oxide measurements to guide treatment in chronic asthma," N. Engl. J. Med. 352, 2163-2173 (2005).
9. Taylor, D.R., "Nitric oxide as a clinical guide for asthma management," J. Allergy. Clin. Immunol. 117, 259-262 (2006).
10. Taylor, D.R., Pijnenburg, M.W. and Smith, A.D., et al., "Exhaled nitric oxide measurements: clinical application and interpretation," Thorax 61, 817-827 (2006).
11. Silkoff, P.E., "Nasal nitric oxide: clue to a diagnosis of ciliary dyskinesia," Chest 126, 1013-1014 (2004)
12. Karadag, B., James, A.J., and Gultekin. E., et al., "Nasal and lower airway level of nitric oxide in children with primary ciliary dyskinesia," Eur. Respir. J. 13, 1402-1405 (1999)
13. Demtröder, W., [Laser Spectroscopy], Springer-Verlag, Berlin (2002).
14. Bozóki, Z., Szakáll, M., Mohácsi, Á., Szabó, G. and Bor, Z.S., "Diode laser based photoacoustic humidity sensors," Sensors and Actuators B 91, 219-226 (2003).
15. Miklós, A., Hess, P., and Bozóki, Z., "Application of acoustic resonators in photoacoustic trace gas analysis and metrology" Rev. Sci. Instrum. 72, 1937 (2001).
16. Rothman, L.S. et. al., "The HITRAN 2008 Molecular Spectroscopic Database," J. Quant. Spectrosc. Radiat. Transfer 110, 533-572 (2009).
17. Germer, M. and Wolff, M., "Quantum cascade laser linewidth investigations for high resolution photoacoustic spectroscopy," Appl. Opt. 48, B80-B86 (2009).