Involvement of pro-nociceptive 5-HT2A receptor in the pathogenesis of medication-overuse headache: Research submission

Headache

Volumn 50, Issue 2, 2010, Pages 185-197

  Supornsilpchai, Weera ^a   Le Grand, Supang M ^a   Srikiatkhachorn, Anan ^a  

^a CHULALONGKORN UNIVERSITY   (Thailand)

Author keywords

5 HT2A receptor; Cortical spreading depression; Fos; Medication overuse headache; Paracetamol; Trigeminal nociception

Indexed keywords

CALCITONIN GENE RELATED PEPTIDE; FREUND ADJUVANT; GENE PRODUCT; KETANSERIN; PARACETAMOL; POTASSIUM CHLORIDE; SEROTONIN 2A ANTAGONIST; SEROTONIN 2A RECEPTOR; SUBSTANCE P; VANILLOID RECEPTOR 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINOCICEPTION; ARTICLE; BLOOD FLOW; BRAIN CORTEX; CERVICAL SPINAL CORD; CONTROLLED STUDY; DRUG DOSE COMPARISON; DRUG INDUCED HEADACHE; ELECTROCORTICOGRAPHY; HEADACHE; HEAT; HINDLIMB; HYPERALGESIA; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; INFLAMMATION; LASER DOPPLER FLOWMETRY; LONG TERM EXPOSURE; NEUROTRANSMISSION; NOCICEPTION; NONHUMAN; ONCOGENE C FOS; PRIORITY JOURNAL; RAT; SEROTONINERGIC SYSTEM; SPREADING CORTICAL DEPRESSION; TRIGEMINUS GANGLION; WISTAR RAT; WITHDRAWAL REFLEX;

ACETAMINOPHEN; ANALGESICS, NON-NARCOTIC; ANIMALS; CEREBRAL CORTEX; CEREBROVASCULAR CIRCULATION; DISEASE MODELS, ANIMAL; HEADACHE DISORDERS, SECONDARY; HYPERALGESIA; INFLAMMATION; INFLAMMATION MEDIATORS; KETANSERIN; MALE; NEURONAL PLASTICITY; NOCICEPTORS; PAIN MEASUREMENT; PAIN THRESHOLD; PROTO-ONCOGENE PROTEINS C-FOS; RATS; RATS, WISTAR; REACTION TIME; RECEPTOR, SEROTONIN, 5-HT2A; SEROTONIN; SEROTONIN ANTAGONISTS; TRIGEMINAL NERVE;

EID: 75849132864     PISSN: 00178748     EISSN: 15264610     Source Type: Journal    
DOI: 10.1111/j.1526-4610.2009.01591.x     Document Type: Article

References (23)

1. Calabresi P, Cupini LM. Medication-overuse headache: Similarities with drug addiction. Trends Pharmacol Sci. 2005 26: 62 68.
2. Sarchielli P, Alberti A, Floridi A, Gallai V. Levels of nerve growth factor in cerebrospinal fluid of chronic daily headache patients. Neurology. 2001 57: 132 134.
3. Gallai V, Alberti A, Gallai B, Coppola F, Floridi A, Sarchielli P. Glutamate and nitric oxide pathway in chronic daily headache: Evidence from cerebrospinal fluid. Cephalalgia. 2003 23: 166 174.
4. Hering R, Glover V, Pattichis K, Catarci T, Steiner TJ. 5HT in migraine with medication-induced headache. Cephalalgia. 1993 13: 410 412.
5. Srikiatkhachorn A, Anthony M. Platelet serotonin in patients with analgesic induced headache. Cephalalgia. 1996 16: 423 426. (Pubitemid 26338473)
6. 2A serotonin receptor in patients with analgesic-induced transformed migraine. Headache. 1998 38: 534 539.
7. Reuter U, Salomone S, Ickenstein GW, Waeber C. Effects of chronic sumatriptan and zolmitriptan treatment on 5-HT receptor expression and function in rats. Cephalalgia. 2004 24: 398 407.
8. Srikiatkhachorn A, Tarasub N, Govitrapong P. Effect of chronic analgesic exposure on the central serotonin system. A possible mechanism of analgesic abuse headache. Headache. 2000 40: 343 350.
9. Bigal ME, Rapoport AM, Sheftell FD, Tepper SJ, Lipton RB. Transformed migraine and medication overuse in a tertiary headache centre-Clinical characteristics and treatment outcomes. Cephalalgia. 2004 24: 483 490.
10. 3A-/-and 5-HTT-/-knock-out male mice. Pain. 2007 130: 235 248.
11. 2A receptor subtype in the peripheral branch of sensory fibers is involved in the potentiation of inflammatory pain in rats. Pain. 2002 99: 133 143.
12. 2A receptor is mainly expressed in nociceptive sensory neurons in rat lumbar dorsal root ganglia. Neuroscience. 2009 161: 838 846.
13. Hong Y, Ji H, Wei H. Topical ketanserin attenuates hyperalgesia and inflammation in arthritis in rats. Pain. 2006 124: 27 33.
14. Nakajima K, Obata H, Ito N, Goto F, Saito S. The nociceptive mechanism of 5-hydroxytryptamine released into the peripheral tissue in acute inflammatory pain in rats. Eur J Pain. 2009 13: 441 447.
15. 2A receptor antagonism attenuates primary thermal hyperalgesia and secondary mechanical allodynia after thermal injury in rats. Pain. 2006 122: 130 136.
16. 2A receptor mRNA in rat spinal dorsal horn and some nuclei of brainstem after peripheral inflammation. Brain Res. 2001 900: 146 151. (Pubitemid 32452275)
17. 2A receptor binding in the human brain and responses to painful heat stimulation. Neuroimage. 2009 44: 1001 1007.
18. Soleimannejad E, Semnanian S, Fathollahi Y, Naghdi N. Microinjection of ritanserin into the dorsal hippocampal CA1 and dentate gyrus decrease nociceptive behavior in adult male rat. Behav Brain Res. 2006 168: 221 225.
19. 2A receptor involvement and Fos expression at the spinal level in vincristine-induced neuropathy in the rat. Pain. 2008 140: 305 322.
20. 2A receptor in 2′,3′-dideoxycytidine- induced neuropathic pain in the rat and the mouse. Pain. 2008 137: 66 80.
21. 2A receptor activation and nitric oxide synthesis: A possible mechanism determining migraine attacks. Headache. 2002 42: 566 574.
22. 2A/2C serotonin receptor, alters the expression of cyclooxygenase-2 in the rat parietal cortex. J Physiol Pharmacol. 2002 53: 395 407.
23. Sandrini M, Vitale G, Pini LA. Central antinociceptive activity of acetylsalicylic acid is modulated by brain serotonin receptor subtypes. Pharmacology. 2002 65: 193 197.