A Case of a GAD Autoantibody-positive NIDDM Patient Treated with a Small Dose of Insulin to Prevent Progression to an Insulin-deficient State

Journal of the Japan Diabetes Society

Volumn 49, Issue 4, 2006, Pages 291-294

[No Author Info available]

Author keywords

[No Author keywords available]

Indexed keywords

EID: 75749150943     PISSN: 0021437X     EISSN: None     Source Type: Journal    
DOI: 10.11213/tonyobyo.49.291     Document Type: Article

References (14)

1. Kawasaki E., Nagataki S. (1996) Japanese type 1 diabetic syndrome. Diabetes Metab Rev 12 : 175-194
2. Zimmet P.Z., Tuomi T., Mackay I.R., Rowley M.J., Knowles W., Cohen M., Lang D.A. (1994) Latent autoimmune diabetes mellitus in adults (LADA) : the role of antibodies to glutamic acid decarboxylase in diagnosis and prediction of insulin dependency. Diabet Med 11: 299-303
3. Kobayashi T., Tamemoto K., Nakanishi K., Kato N., Okubo M., Kajio H., Sugimoto T., Murase T., Kosaka K. (1993) Immunogenetic and clinical characterization of slowly progressive IDDM. Diabetes Care 16 : 780-788
4. Maruyama T., Shimada A., Kanatsuka A., Kasuga A., Takei I., Yokoyama J., Kobayashi T. (2003) Multicenter prevention trial of slowly progressive type 1 diabetes with small dose of insulin (the Tokyo study) : preliminary report. Ann N Y Acad Sci 1005 : 362-369
5. Sera Y., Kawasaki E., Abiru N., Ozaki M., Abe T., Takino H., Kondo H., Yamasaki H., Yamaguchi Y., Akazawa S., Nagataki S., Uchigata Y., Matsuura N., Eguchi K. (1999) Autoantibodies to multiple islet autoantigens in patients with abrupt onset type 1 diabetes and diabetes diagnosed with urinary glucose screening. J Autoimmun 13:257-265
6. Awata T., Kanazawa Y. (1994) Genetic markers for insulin-dependent diabetes mellitus in Japanese. Diabetes Res Clin Pract 24 Suppl: S83-S87
7. Diabetes Prevention Trial-Type 1 Diabetes Study Group (2002) Effects of insulin in relatives of patients with type 1 diabetes mellitus. N Engl J Med 346: 1685-1691
8. Skyler J.S., Krischer J.P., Wolfsdorf J., Cowie C., Palmer J.P., Greenbaum C., Cuthbertson D., Rafkin-Mervis L.E., Chase H.P., Leschek E. (2005) Effects of oral insulin in relatives of patients with type 1 diabetes: The Diabetes Prevention Trial-Type 1. Diabetes Care 28: 1068-1076
9. Gale E.A., Bingley P.J., Emmett C.L., Collier T.; European Nicotinamide Diabetes Intervention Trial (ENDIT) Group (2004) European Nicotinamide Diabetes Intervention Trial (ENDIT) : a randomised controlled trial of intervention before the onset of type 1 diabetes. Lancet 363:925-931
10. Keymeulen B., Vandemeulebroucke E., Ziegler A.G., Mathieu C., Kaufman L., Hale G., Gorus F., Goldman M., Walter M., Candon S., Schandene L., Crenier L., De Block C., Seigneurin J.M., De Pauw P., Pierard D., Weets I., Rebello P., Bird P., Berrie E., Frewin M., Waldmann H., Bach J.F., Pipeleers D., Chatenoud L. (2005) Insulin needs after CD3-antibody therapy in new-onset type 1 diabetes. N Engl J Med 352 : 2598-2608
11. Greenbaum C.J., Eisenbarth G., Atkinson M., Yu L., Babu S., Schatz D., Zeidler A., Orban T., Wasserfall C., Cuthbertson D., Krischer J.; DPT-1 study group. (2005) High frequency of abnormal glucose tolerance in DQA1*0102/DQB1*0602 relatives identified as part of the Diabetes Prevention Trial-Type 1 Diabetes. Diabetologia 48:68-74
12. Takeda H., Kawasaki E., Shimizu I., Konoue E., Fujiyama M., Murao S., Tanaka K., Mori K., Tarumi Y., Seto I., Fujii Y., Kato K., Kondo S., Takada Y., Kitsuki N., Kaino Y., Kida K., Hashimoto N., Yamane Y., Yamawaki T., Onuma H., Nishimiya T., Osawa H., Saito Y., Makino H.; Ehime Study. (2002) Clinical, autoimmune, and genetic characteristics of adult-onset diabetic patients with GAD autoantibodies in Japan (Ehime Study). Diabetes Care 25:995-1001
13. Turner R., Stratton I., Horton V., Manley S., Zimmet P., Mackay I.R., Shattock M., Bottazzo G.F., Holman R. (1997) UKPDS 25 : autoantibodies to islet-cell cytoplasm and glutamic acid decarboxylase for prediction of insulin requirement in type 2 diabetes. UK Prospective Diabetes Study Group. Lancet 350 :1288-1293
14. Kawasaki E., Abiru N., Ide A., Sun F., Yamaguchi Y., Eguchi K. (2002) Epitope analysis of GAD65 autoantibodies predicts the risk for insulin requirement in LADA. Diab Metab Res Rev 18 Suppl 4: S38