Alopecia: Association with resistance to thyroid hormones

Journal of Pediatric Endocrinology and Metabolism

Volumn 22, Issue 11, 2009, Pages 1075-1081

  Guran, Tulay ^a   Bircan, Rifat ^b   Turan, Serap ^a   Bereket, Abdullah ^a  

^a MARMARA UNIVERSITY   (Turkey)

^b NAMIK KEMAL UNIVERSITY   (Turkey)

Author keywords

Alopecia; Alopecia totalis universalis; Hairless gene; Resistance to thyroid hormone; Thyroid hormone receptor beta (TR ) mutation

Indexed keywords

DERMATOLOGICAL AGENT; GENOMIC DNA; MINOXIDIL; STEROID; THYROID HORMONE; THYROID HORMONE RECEPTOR BETA; THYROTROPIN;

ALOPECIA AREATA; ARTICLE; CASE REPORT; CHILD; CLINICAL FEATURE; DNA SEQUENCE; FAMILY HISTORY; GENE ACTIVITY; GENE IDENTIFICATION; GOITER; HAIR FOLLICLE; HUMAN; MALE; MISSENSE MUTATION; MUTATIONAL ANALYSIS; RELATIVE; SCHOOL CHILD; SEQUENCE ANALYSIS; THYROID ADENOMA; THYROID HORMONE BLOOD LEVEL; THYROID HORMONE RESISTANCE; THYROIDECTOMY; THYROTROPIN BLOOD LEVEL;

EID: 75749149775     PISSN: 0334018X     EISSN: None     Source Type: Journal    
DOI: 10.1515/JPEM.2009.22.11.1075     Document Type: Article

References (22)

1. Refetoff S, DeWind LT, DeGroot LJ. Familial syndrome combining deaf-mutism, stuppled epiphyses, goiter and abnormally high PBI: possible target organ refractoriness to thyroid hormone. J Clin Endocrinol Metab 1967; 27: 279-294.
2. La Franchi SH, Snyder DB, Sesser DE, Skeels MR, Singh N, Brent GA. Follow-up of newborns with elevated screening T4 concentrations. J Pediatr 2003; 143: 296-301.
3. Brucker-Davis F, Skarulis MC, Grace MB, Benichou J, Hauser P, Wiggs E, Weintraub BD. Genetic and clinical features of 42 kindreds with resistance to thyroid hormone. The National Institutes of Health Prospective Study. Ann Intern Med 1995; 123: 572-583.
4. th Ed. Philadelphia, PA: Lippincott, Williams and Wilkins, 2005; 1109-1129.
5. Refetoff S. Resistance to thyroid hormone: one of several defects causing reduced sensitivity to thyroid hormone. Nat Clin Pract Endocrinol Metab 2008; 4: 1.
6. Shellow WV, Edwards JE, Koo JY. Profile of alopecia areata: a questionnaire analysis of patient and family. Int J Dermatol 1992; 31: 186-189.
7. Roelandt T, Kraemer L, Van Neste D, Lissens W, Roseeuw D, Christiano AM, Hachem JP. Novel mutation in the human hairless gene once more erroneously diagnosed and treated as 'alopecia areata'. Br J Dermatol 2008; 158: 834-835.
8. Neyzi O, Furman A, Bundak R, Gunoz H, Darendeliler F, Bas F. Growth references for Turkish children aged 6 to 18 years. Acta Paediatr 2006; 95: 1635-1641.
9. John SW, Weitzner G, Rozen R, Scriver CR. A rapid procedure for extracting genomic DNA from leukocytes. Nucleic Acids Res 1991; 19: 408.
10. Adams M, Matthews C, Collingwood TN, Tone Y, Beck-Peccoz P, Chatterjee VK. Genetic analysis of 29 kindreds with generalized and pituitary resistance to thyroid hormone. Identification of thirteen novel mutations in the thyroid hormone receptor beta gene. J Clin Invest 1994; 94: 506-515.
11. Sato H, Koike Y, Honma M, Yagame M, Ito K. Evaluation of thyroid hormone action in a case of generalized resistance to thyroid hormone with chronic thyroiditis: discovery of a novel heterozygous missense mutation (G347A). Endocr J 2007; 54: 727-732.
12. Kurtev A, Iliev E. Thyroid autoimmunity in children and adolescents with alopecia areata. Int J Dermatol 2005; 44: 457-461.
13. Nanda A, Alsaleh QA, Al-Hasawi F, Al-Muzairai I. Thyroid function, autoantibodies, and HLA tissue typing in children with alopecia areata. Pediatr Dermatol 2002; 19: 486-491.
14. Kakourou T, Karachristou K, Chrousos G. A case series of alopecia areata in children: impact of personal and family history of stress and autoimmunity. J Eur Acad Dermatol Venereol 2007; 21: 356-359.
15. Olateju TO, Vanderpump MP. Thyroid hormone resistance. Ann Clin Biochem 2006; 43: 431-440.
16. Billoni N, Buan B, Gautier B, Gaillard O, Mahe YF, Bernard BA. Thyroid hormone receptor β1 is expressed in the human hair follicle. Br J Dermatol 2000; 142: 645-652.
17. Zlotogorski A, Ahmad W, Christiano AM. Congenital atrichia in five Arab Palestinian families resulting from a deletion mutation in the hairless gene. Hum Genet 1998; 103: 400-404.
18. Ramos HE, Weiss RE. Regulation of nuclear co-activator and corepressor expression in mouse cerebellum by thyroid tissue. Thyroid 2006; 16: 211-216.
19. Potter GB, Zarach JM, Sisk JM, Thompson CC. The thyroid hormone-regulated corepressor hairless associates with histone deacetylases in neonatal rat brain. Mol Endocrinol 2002; 16: 2547-2560.
20. Cichon S, Anker M, Vogt IR, Rohleder H, Pützstück M, Hillmer A, Farooqi SA, Al-Dhafri KS, Ahmad M, Haque S, Rietschel M, Propping P, Kruse R, Nöthen MM. Cloning, genomic organization, alternative transcripts and mutational analysis of the gene responsible for autosomal recessive universal congenital alopecia. Hum Mol Genet 1998; 7: 1671-1679.
21. Hatipoglu N, Kurtoglu S, Keskin M, Kendirci M. An occasional side effect in the treatment of congenital hypothyroidism: hair loss. Eur J Pediatr 2006; 165: 500-501.
22. Mamanasiri S, Yesil S, Dumitrescu AM, Liao XH, Demir T, Weiss RE, Refetoff S. Mosaicism of a thyroid hormone receptor-beta gene mutation in resistance to thyroid hormone. J Clin Endocrinol Metab 2006; 91: 3471-3477.