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Volumn 55, Issue 3, 2009, Pages 289-300

Pathophysiology and management of gastroesophageal reflux disease

Author keywords

Esophageal sphincter, lower; Gastroesophageal reflux; Hernia, hiatal

Indexed keywords

4 AMINOBUTYRIC ACID RECEPTOR BLOCKING AGENT; ADX 10059; BACLOFEN; PROTON PUMP INHIBITOR; UNCLASSIFIED DRUG;

EID: 75749139774     PISSN: 00264776     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (21)

References (97)
  • 1
    • 53049088882 scopus 로고    scopus 로고
    • American Gastroenterological Association Medical Position Statement on the management of gastroesophageal reflux disease
    • Kahrilas PJ, Shaheen NJ, Vaezi MF, Hiltz SW, Black E, Modlin IM et al. American Gastroenterological Association Medical Position Statement on the management of gastroesophageal reflux disease. Gastroenterology 2008;135:1383-1.
    • (2008) Gastroenterology , vol.135 , pp. 1383-1391
    • Kahrilas, P.J.1    Shaheen, N.J.2    Vaezi, M.F.3    Hiltz, S.W.4    Black, E.5    Modlin, I.M.6
  • 3
    • 17644416461 scopus 로고    scopus 로고
    • Epidemiology of gastroesophageal reflux disease: A systematic review
    • Dent J, El-Serag HB, Wallander MA, Johansson S. Epidemiology of gastroesophageal reflux disease: a systematic review. Gut 2005;54:710-7.
    • (2005) Gut , vol.54 , pp. 710-717
    • Dent, J.1    El-Serag, H.B.2    Wallander, M.A.3    Johansson, S.4
  • 4
    • 0030962574 scopus 로고    scopus 로고
    • Speed of healing and symptom relief in grade II to IV gastroesophageal reflux disease: A meta-analysis
    • Chiba N, De Gara CJ, Wilkinson JM, Hunt RH. Speed of healing and symptom relief in grade II to IV gastroesophageal reflux disease: a meta-analysis. Gastroenterology 1997;112:1798-810.
    • (1997) Gastroenterology , vol.112 , pp. 1798-1810
    • Chiba, N.1    De Gara, C.J.2    Wilkinson, J.M.3    Hunt, R.H.4
  • 6
    • 34249854930 scopus 로고    scopus 로고
    • Pharmacological dissection of the human gastro-oesophageal segment into three sphincteric components
    • Brasseur JG, Ulerich R, Dai Q, Patel DK, Soliman AM, Miller LS. Pharmacological dissection of the human gastro-oesophageal segment into three sphincteric components. J Physiol 2007;580:961-75.
    • (2007) J Physiol , vol.580 , pp. 961-975
    • Brasseur, J.G.1    Ulerich, R.2    Dai, Q.3    Patel, D.K.4    Soliman, A.M.5    Miller, L.S.6
  • 7
    • 0003442818 scopus 로고    scopus 로고
    • 9th ed. Philadelphia: Lippincott Williams and Wilkins;
    • Sadler TW. Langman's medical embryology. 9th ed. Philadelphia: Lippincott Williams and Wilkins; 2002. p. 217-9.
    • (2002) Langman's medical embryology , pp. 217-219
    • Sadler, T.W.1
  • 8
    • 0036773226 scopus 로고    scopus 로고
    • The diaphragm: Two physiological muscles in one
    • Pickering M, Jones JF. The diaphragm: two physiological muscles in one. J Anat 2002;201:305-12.
    • (2002) J Anat , vol.201 , pp. 305-312
    • Pickering, M.1    Jones, J.F.2
  • 9
    • 38149053574 scopus 로고    scopus 로고
    • Dorsal motor nucleus of the vagus: A site for evoking simultaneous changes in crural diaphragm activity, lower esophageal sphincter pressure, and fundus tone
    • Niedringhaus M, Jackson PG, Evans SR, Verbalis JG, Gillis RA, Sahibzada N. Dorsal motor nucleus of the vagus: a site for evoking simultaneous changes in crural diaphragm activity, lower esophageal sphincter pressure, and fundus tone. Am J Physiol Regul Integr Comp Physiol 2008;294:R121-R31.
    • (2008) Am J Physiol Regul Integr Comp Physiol , vol.294
    • Niedringhaus, M.1    Jackson, P.G.2    Evans, S.R.3    Verbalis, J.G.4    Gillis, R.A.5    Sahibzada, N.6
  • 10
    • 0023910655 scopus 로고
    • Electrical and mechanical activity in the human lower esophageal sphincter during diaphragmatic contraction
    • Mitral RK, Rochester DF, McCallum RW. Electrical and mechanical activity in the human lower esophageal sphincter during diaphragmatic contraction. J Clin Invest 1988;81:1182-9.
    • (1988) J Clin Invest , vol.81 , pp. 1182-1189
    • Mitral, R.K.1    Rochester, D.F.2    McCallum, R.W.3
  • 11
    • 0028789247 scopus 로고
    • Effect of atropine on the frequency of reflux and transient lower esophageal sphincter relaxation in normal subjects
    • Mittal RK, Holloway R, Dent J. Effect of atropine on the frequency of reflux and transient lower esophageal sphincter relaxation in normal subjects. Gastroenterology 1995;109:1547-54.
    • (1995) Gastroenterology , vol.109 , pp. 1547-1554
    • Mittal, R.K.1    Holloway, R.2    Dent, J.3
  • 13
  • 14
    • 0028891589 scopus 로고
    • Criteria for objective definition of transient lower esophageal sphincter relaxation
    • Holloway RH, Penagini R, Ireland AC. Criteria for objective definition of transient lower esophageal sphincter relaxation. Am J Physiol 1995;268:G128-G33.
    • (1995) Am J Physiol , vol.268
    • Holloway, R.H.1    Penagini, R.2    Ireland, A.C.3
  • 16
    • 0034821416 scopus 로고    scopus 로고
    • Transient lower esophageal sphincter relaxations: How many or how harmful?
    • Sifrim D, Holloway R. Transient lower esophageal sphincter relaxations: how many or how harmful? Am J Gastroenterol 2001;96:2529-32.
    • (2001) Am J Gastroenterol , vol.96 , pp. 2529-2532
    • Sifrim, D.1    Holloway, R.2
  • 17
    • 0034833952 scopus 로고    scopus 로고
    • Transient lower esophageal sphincter relaxations are no more frequent in patients with gastroesophageal reflux disease than in asymptomatic volunteers
    • Trodgill NJ, Riley SA. Transient lower esophageal sphincter relaxations are no more frequent in patients with gastroesophageal reflux disease than in asymptomatic volunteers. Am J Gastroenterol 2O01;96:2569-74.
    • Am J Gastroenterol 2O01 , vol.96 , pp. 2569-2574
    • Trodgill, N.J.1    Riley, S.A.2
  • 18
    • 0032213642 scopus 로고    scopus 로고
    • Page AJ, Blackshaw LA. An in vitro study of the properties of vagal afferent fibres innervating the ferret oesophagus and stomach. J Physiol 1998;512(Pt 3):907-16.
    • Page AJ, Blackshaw LA. An in vitro study of the properties of vagal afferent fibres innervating the ferret oesophagus and stomach. J Physiol 1998;512(Pt 3):907-16.
  • 19
    • 42949108690 scopus 로고    scopus 로고
    • A unique longitudinal muscle contraction pattern associated with transient lower esophageal sphincter relaxation
    • Babaei A, Bhargava V, Korsapati H, Zheng WH, Mittal RK. A unique longitudinal muscle contraction pattern associated with transient lower esophageal sphincter relaxation. Gastroenterology 2008;134:1322-31.
    • (2008) Gastroenterology , vol.134 , pp. 1322-1331
    • Babaei, A.1    Bhargava, V.2    Korsapati, H.3    Zheng, W.H.4    Mittal, R.K.5
  • 20
    • 0036163950 scopus 로고    scopus 로고
    • Transient lower oesophageal sphincter relaxations a pharmacological target for gastro-oesophageal reflux disease?
    • Hirsch DP, Tytgat GN, Boeckxstaens GE. Transient lower oesophageal sphincter relaxations a pharmacological target for gastro-oesophageal reflux disease? Aliment Pharmacol Ther 2002;16:17-26.
    • (2002) Aliment Pharmacol Ther , vol.16 , pp. 17-26
    • Hirsch, D.P.1    Tytgat, G.N.2    Boeckxstaens, G.E.3
  • 22
    • 0034967788 scopus 로고    scopus 로고
    • Hiatal hernia size is the dominant determinant of esophagitis presence and severity in gastroesophageal reflux disease
    • Jones MP, Sloan SS, Rabine JC, Ebert CC, Huang CF, Kahrilas PJ. Hiatal hernia size is the dominant determinant of esophagitis presence and severity in gastroesophageal reflux disease. Am J Gastroenterol 2001;96:1711-7.
    • (2001) Am J Gastroenterol , vol.96 , pp. 1711-1717
    • Jones, M.P.1    Sloan, S.S.2    Rabine, J.C.3    Ebert, C.C.4    Huang, C.F.5    Kahrilas, P.J.6
  • 24
    • 32044464312 scopus 로고    scopus 로고
    • Intermittent spatial separation of diaphragm and lower esophageal sphincter favors acidic and weakly acidic reflux
    • Bredenoord AJ, Weusten BL, Timmer R, Smout AJ. Intermittent spatial separation of diaphragm and lower esophageal sphincter favors acidic and weakly acidic reflux. Gastroenterology 2006;130:334-40.
    • (2006) Gastroenterology , vol.130 , pp. 334-340
    • Bredenoord, A.J.1    Weusten, B.L.2    Timmer, R.3    Smout, A.J.4
  • 25
    • 18744400096 scopus 로고    scopus 로고
    • Impaired egress rather than increased access: An important independent predictor of erosive oesophagitis
    • Jones MP, Sloan SS, Jovanovic B, Kahrilas PJ. Impaired egress rather than increased access: an important independent predictor of erosive oesophagitis. Neurogastroenterol Motil 2002;14:625-31.
    • (2002) Neurogastroenterol Motil , vol.14 , pp. 625-631
    • Jones, M.P.1    Sloan, S.S.2    Jovanovic, B.3    Kahrilas, P.J.4
  • 26
    • 0023206072 scopus 로고
    • Identification and mechanism of delayed esophageal acid clearance in subjects with hiatus hernia
    • Mittal RK, Lange RC, McCallum RW. Identification and mechanism of delayed esophageal acid clearance in subjects with hiatus hernia. Gastroenterology 1987;92:130-5.
    • (1987) Gastroenterology , vol.92 , pp. 130-135
    • Mittal, R.K.1    Lange, R.C.2    McCallum, R.W.3
  • 27
    • 0034464103 scopus 로고    scopus 로고
    • Excess gastroesophageal reflux in patients with hiatus hernia is caused by mechanisms other than transient LES relaxations
    • van Herwaarden MA, Samsom M, Smout AJ. Excess gastroesophageal reflux in patients with hiatus hernia is caused by mechanisms other than transient LES relaxations. Gastroenterology 2000;119:1439-46.
    • (2000) Gastroenterology , vol.119 , pp. 1439-1446
    • van Herwaarden, M.A.1    Samsom, M.2    Smout, A.J.3
  • 28
    • 71949116252 scopus 로고    scopus 로고
    • The position of the acid pocket as a major risk factor for acidic reflux in healthy subject and GERD patients
    • In press
    • Beaumont H, Boeckxstaens GE. The position of the acid pocket as a major risk factor for acidic reflux in healthy subject and GERD patients. Gut 2009. In press
    • (2009) Gut
    • Beaumont, H.1    Boeckxstaens, G.E.2
  • 29
    • 0027970569 scopus 로고
    • Esophageal shortening induced by short-term intraluminal acid perfusion in opossum: A cause for hiatus hernia?
    • Paterson WG, Kolyn DM. Esophageal shortening induced by short-term intraluminal acid perfusion in opossum: a cause for hiatus hernia? Gastroenterology 1994;107:1736-40.
    • (1994) Gastroenterology , vol.107 , pp. 1736-1740
    • Paterson, W.G.1    Kolyn, D.M.2
  • 31
    • 10644282117 scopus 로고    scopus 로고
    • Review article: The pathophysiology of gastro-oesophageal reflux disease - esophageal manifestations
    • Castell DO, Murray JA, Tutuian R, Orlando RC, Arnold R. Review article: the pathophysiology of gastro-oesophageal reflux disease - esophageal manifestations. Aliment Pharmacol Ther 2004;20(Suppl 9): 14-25.
    • (2004) Aliment Pharmacol Ther , vol.20 , Issue.SUPPL. 9 , pp. 14-25
    • Castell, D.O.1    Murray, J.A.2    Tutuian, R.3    Orlando, R.C.4    Arnold, R.5
  • 35
    • 10644294645 scopus 로고    scopus 로고
    • Review article: Sleep and its relationship to gastro-oesophageal reflux
    • Orr WC, Heading R, Johnson LF, Kryger M. Review article: sleep and its relationship to gastro-oesophageal reflux. Aliment Pharmacol Ther 2004;20(Suppl 9):39-46.
    • (2004) Aliment Pharmacol Ther , vol.20 , Issue.SUPPL. 9 , pp. 39-46
    • Orr, W.C.1    Heading, R.2    Johnson, L.F.3    Kryger, M.4
  • 36
    • 0035698273 scopus 로고    scopus 로고
    • Predominant nocturnal acid reflux in patients with Los Angeles grade C and D reflux esophagitis
    • Adachi K, Fujishiro H, Katsube T, Yuki M, Ono M, Kawamura A et al. Predominant nocturnal acid reflux in patients with Los Angeles grade C and D reflux esophagitis. J Gastroenterol Hepatol 2001;16:1191-6.
    • (2001) J Gastroenterol Hepatol , vol.16 , pp. 1191-1196
    • Adachi, K.1    Fujishiro, H.2    Katsube, T.3    Yuki, M.4    Ono, M.5    Kawamura, A.6
  • 37
    • 0034793656 scopus 로고    scopus 로고
    • Unbuffered highly acidic gastric juice exists at the gastroesophageal junction after a meal
    • Fletcher J, Wirz A, Young J, Vallance R, McColl KE. Unbuffered highly acidic gastric juice exists at the gastroesophageal junction after a meal. Gastroenterology 2001;121:775-83.
    • (2001) Gastroenterology , vol.121 , pp. 775-783
    • Fletcher, J.1    Wirz, A.2    Young, J.3    Vallance, R.4    McColl, K.E.5
  • 38
    • 75749087461 scopus 로고    scopus 로고
    • Scintigraphic imaging of the acid pocket: An enlarged pocket with acid coating the distal esophagus in GERD patients with hiatal hernia
    • In press
    • Beaumont H, Boeckxstaens GE. Scintigraphic imaging of the acid pocket: an enlarged pocket with acid coating the distal esophagus in GERD patients with hiatal hernia. Gut 2009 In press.
    • (2009) Gut
    • Beaumont, H.1    Boeckxstaens, G.E.2
  • 39
    • 0346374660 scopus 로고    scopus 로고
    • Delayed gastric emptying in gastroesophageal reflux disease: Reassessment with new methods and symptomatic correlations
    • Buckles DC, Sarosiek I, McMillin C, McCallum RW. Delayed gastric emptying in gastroesophageal reflux disease: reassessment with new methods and symptomatic correlations. Am J Med Sci 2004;327:1-4.
    • (2004) Am J Med Sci , vol.327 , pp. 1-4
    • Buckles, D.C.1    Sarosiek, I.2    McMillin, C.3    McCallum, R.W.4
  • 41
    • 21444449227 scopus 로고    scopus 로고
    • Gastroesophageal reflux and gastric emptying, revisited
    • Emerenziani S, Sifrim D. Gastroesophageal reflux and gastric emptying, revisited. Curr Gastroenterol Rep 2005;7:190-5.
    • (2005) Curr Gastroenterol Rep , vol.7 , pp. 190-195
    • Emerenziani, S.1    Sifrim, D.2
  • 43
    • 0027235848 scopus 로고
    • Rabbit esophageal cells show regulatory volume decrease: Ionic basis and effect of pH
    • Snow JC, Goldstein JL, Schmidt LN, Lisitza P, Layden TJ. Rabbit esophageal cells show regulatory volume decrease: ionic basis and effect of pH. Gastroenterology 1993;105:102-10.
    • (1993) Gastroenterology , vol.105 , pp. 102-110
    • Snow, J.C.1    Goldstein, J.L.2    Schmidt, L.N.3    Lisitza, P.4    Layden, T.J.5
  • 44
    • 33747597566 scopus 로고    scopus 로고
    • Review article: Human pepsins - their multiplicity, function and role in reflux disease
    • Roberts NB. Review article: human pepsins - their multiplicity, function and role in reflux disease. Aliment Pharmacol Ther 2006;24(Suppl 2):2-9.
    • (2006) Aliment Pharmacol Ther , vol.24 , Issue.SUPPL. 2 , pp. 2-9
    • Roberts, N.B.1
  • 45
    • 0029050520 scopus 로고
    • Role of acid and duodenogastric reflux in esophageal mucosal injury: A review of animal and human studies
    • Vaezi MF, Singh S, Richter JE. Role of acid and duodenogastric reflux in esophageal mucosal injury: a review of animal and human studies. Gastroenterology 1995;108:1897-907.
    • (1995) Gastroenterology , vol.108 , pp. 1897-1907
    • Vaezi, M.F.1    Singh, S.2    Richter, J.E.3
  • 46
    • 48249124148 scopus 로고    scopus 로고
    • Multivariate analysis of the association of acid and duodeno-gastro-esophageal reflux exposure with the presence of oesophagitis, the severity of oesophagitis and Barrett's oesophagus
    • Koek GH, Sifrim D, Lerut T, Janssens J, Tack J. Multivariate analysis of the association of acid and duodeno-gastro-esophageal reflux exposure with the presence of oesophagitis, the severity of oesophagitis and Barrett's oesophagus. Gut 2008;57:1056-64.
    • (2008) Gut , vol.57 , pp. 1056-1064
    • Koek, G.H.1    Sifrim, D.2    Lerut, T.3    Janssens, J.4    Tack, J.5
  • 49
    • 0025942449 scopus 로고
    • Esophageal epithelial defense against acid injury
    • Orlando RC. Esophageal epithelial defense against acid injury. J Clin Gastroenterol 1991;13 Suppl 2:S1-S5.
    • (1991) J Clin Gastroenterol , vol.13 , Issue.SUPPL. 2
    • Orlando, R.C.1
  • 50
    • 0032016408 scopus 로고    scopus 로고
    • Review article: Oesophageal mucosal resistance
    • Orlando RC. Review article: oesophageal mucosal resistance. Aliment Pharmacol Ther 1998;12:191-7.
    • (1998) Aliment Pharmacol Ther , vol.12 , pp. 191-197
    • Orlando, R.C.1
  • 51
    • 0031056628 scopus 로고    scopus 로고
    • HCl-induced cell edema in primary cultured rabbit esophageal epithelium
    • Tobey NA, Koves G, Orlando RC. HCl-induced cell edema in primary cultured rabbit esophageal epithelium. Gastroenterology 1997;112:847-54.
    • (1997) Gastroenterology , vol.112 , pp. 847-854
    • Tobey, N.A.1    Koves, G.2    Orlando, R.C.3
  • 52
    • 34250826458 scopus 로고    scopus 로고
    • Review article: The pathophysiology of gastro-oesophageal reflux disease
    • Boeckxstaens GE. Review article: the pathophysiology of gastro-oesophageal reflux disease. Aliment Pharmacol Ther 2007;26:149-60.
    • (2007) Aliment Pharmacol Ther , vol.26 , pp. 149-160
    • Boeckxstaens, G.E.1
  • 53
    • 34249693533 scopus 로고    scopus 로고
    • Circumferential and axial distribution of esophageal mucosal damage in reflux disease
    • Edebo A, Vieth M, Tam W, Bruno M, van Berkel AM, Stolte M et al. Circumferential and axial distribution of esophageal mucosal damage in reflux disease. Dis Esophagus 2007;20:232-8.
    • (2007) Dis Esophagus , vol.20 , pp. 232-238
    • Edebo, A.1    Vieth, M.2    Tam, W.3    Bruno, M.4    van Berkel, A.M.5    Stolte, M.6
  • 54
    • 41849125260 scopus 로고    scopus 로고
    • Esophageal dilated intercellular spaces (DIS) and non-erosive reflux disease
    • Malenstein H, Farre R, Sifrim D. Esophageal dilated intercellular spaces (DIS) and non-erosive reflux disease. Am J Gastroenterol 2008;103:1021-8.
    • (2008) Am J Gastroenterol , vol.103 , pp. 1021-1028
    • Malenstein, H.1    Farre, R.2    Sifrim, D.3
  • 56
    • 52649117602 scopus 로고    scopus 로고
    • Short exposure of oesophageal mucosa to bile acids, both in acidic and weakly acidic conditions, can impair mucosal integrity and provoke dilated intercellular spaces
    • Farre R, van MH, De VR, Geboes K, Depoortere I, Vanden BP et al. Short exposure of oesophageal mucosa to bile acids, both in acidic and weakly acidic conditions, can impair mucosal integrity and provoke dilated intercellular spaces. Gut 2008;57:1366-74.
    • (2008) Gut , vol.57 , pp. 1366-1374
    • Farre, R.1    van MH, D.V.2    Geboes, K.3    Depoortere, I.4    Vanden, B.P.5
  • 57
    • 34548125019 scopus 로고    scopus 로고
    • Critical role of stress in increased oesophageal mucosa permeability and dilated intercellular spaces
    • Farre R, De VR, Geboes K, Verbecke K, Vanden BP, Depoortere I et al. Critical role of stress in increased oesophageal mucosa permeability and dilated intercellular spaces. Gut 2007;56:1191-7.
    • (2007) Gut , vol.56 , pp. 1191-1197
    • Farre, R.1    De, V.R.2    Geboes, K.3    Verbecke, K.4    Vanden, B.P.5    Depoortere, I.6
  • 58
    • 16844376429 scopus 로고    scopus 로고
    • Reversibility of GERD ultrastructural alterations and relief of symptoms after omeprazole treatment
    • Calabrese C, Bortolotti M, Fabbri A, Areni A, Cenacchi G, Scialpi C et al. Reversibility of GERD ultrastructural alterations and relief of symptoms after omeprazole treatment. Am J Gastroenterol 2005;100:537-42.
    • (2005) Am J Gastroenterol , vol.100 , pp. 537-542
    • Calabrese, C.1    Bortolotti, M.2    Fabbri, A.3    Areni, A.4    Cenacchi, G.5    Scialpi, C.6
  • 60
    • 42549170656 scopus 로고    scopus 로고
    • Visceral hypersensitivity in non-erosive reflux disease
    • Knowles CH, Aziz Q. Visceral hypersensitivity in non-erosive reflux disease. Gut 2008;57:674-83.
    • (2008) Gut , vol.57 , pp. 674-683
    • Knowles, C.H.1    Aziz, Q.2
  • 61
    • 0345307670 scopus 로고    scopus 로고
    • Acid-sensitive ion channels in gastrointestinal function
    • Holzer P. Acid-sensitive ion channels in gastrointestinal function. Curr Opin Pharmacol 2003;3:618-25.
    • (2003) Curr Opin Pharmacol , vol.3 , pp. 618-625
    • Holzer, P.1
  • 63
    • 33644603970 scopus 로고    scopus 로고
    • Capsaicin receptor (TRPV1) and non-erosive reflux disease
    • Bhat YM, Bielefeldt K. Capsaicin receptor (TRPV1) and non-erosive reflux disease. Eur J Gastroenterol Hepatol 2006;18:263-70.
    • (2006) Eur J Gastroenterol Hepatol , vol.18 , pp. 263-270
    • Bhat, Y.M.1    Bielefeldt, K.2
  • 64
    • 0034734670 scopus 로고    scopus 로고
    • Contribution of central sensitisation to the development of non-cardiac chest pain
    • Sarkar S, Aziz Q, Woolf CJ, Hobson AR, Thompson DG. Contribution of central sensitisation to the development of non-cardiac chest pain. Lancet 2000;356: 1154-9.
    • (2000) Lancet , vol.356 , pp. 1154-1159
    • Sarkar, S.1    Aziz, Q.2    Woolf, C.J.3    Hobson, A.R.4    Thompson, D.G.5
  • 65
    • 27944443168 scopus 로고    scopus 로고
    • The effect of psychological stress on symptom severity and perception in patients with gastroesophageal reflux
    • Wright CE, Ebrecht M, Mitchell R, Anggiansah A, Weinman J. The effect of psychological stress on symptom severity and perception in patients with gastroesophageal reflux. J Psychosom Res 2005;59:415-24.
    • (2005) J Psychosom Res , vol.59 , pp. 415-424
    • Wright, C.E.1    Ebrecht, M.2    Mitchell, R.3    Anggiansah, A.4    Weinman, J.5
  • 66
    • 50149096408 scopus 로고    scopus 로고
    • Maintenance treatment for GERD: Residual symptoms are associated with psychological distress
    • Velden vd A, de Wit NJ, Quartero AO, Grobbee DE, Numans ME. Maintenance treatment for GERD: residual symptoms are associated with psychological distress. Digestion 2008;77:207-13-
    • (2008) Digestion , vol.77 , pp. 207-213
    • Velden vd, A.1    de Wit, N.J.2    Quartero, A.O.3    Grobbee, D.E.4    Numans, M.E.5
  • 68
    • 39749125041 scopus 로고    scopus 로고
    • The effect of auditory stress on perception of intraesophageal acid in patients with gastroesophageal reflux disease
    • Fass R, Naliboff BD, Fass SS, Peleg N, Wendel C, Malagon IB et al. The effect of auditory stress on perception of intraesophageal acid in patients with gastroesophageal reflux disease. Gastroenterology 2008;134:696-705.
    • (2008) Gastroenterology , vol.134 , pp. 696-705
    • Fass, R.1    Naliboff, B.D.2    Fass, S.S.3    Peleg, N.4    Wendel, C.5    Malagon, I.B.6
  • 69
    • 1842539505 scopus 로고    scopus 로고
    • Short-term treatment with proton-pump inhibitors as a test for gastroesophageal reflux disease: A meta-analysis of diagnostic test characteristics
    • Numans ME, Lau J, de Wit NJ, Bonis PA. Short-term treatment with proton-pump inhibitors as a test for gastroesophageal reflux disease: a meta-analysis of diagnostic test characteristics. Ann Intern Med 2004;140:518-27.
    • (2004) Ann Intern Med , vol.140 , pp. 518-527
    • Numans, M.E.1    Lau, J.2    de Wit, N.J.3    Bonis, P.A.4
  • 70
    • 23844454032 scopus 로고    scopus 로고
    • Review article: How valuable are proton-pump inhibitors in establishing a diagnosis of gastro-oesophageal reflux disease?
    • Vakil N. Review article: how valuable are proton-pump inhibitors in establishing a diagnosis of gastro-oesophageal reflux disease? Aliment Pharmacol Ther 2005;22(Suppl 1):64-9.
    • (2005) Aliment Pharmacol Ther , vol.22 , Issue.SUPPL. 1 , pp. 64-69
    • Vakil, N.1
  • 71
    • 33745960986 scopus 로고    scopus 로고
    • Management of gastroesophageal reflux disease
    • Liu JJ, Saltzman JR. Management of gastroesophageal reflux disease. South Med J 2006;99:735-41.
    • (2006) South Med J , vol.99 , pp. 735-741
    • Liu, J.J.1    Saltzman, J.R.2
  • 72
    • 33746477131 scopus 로고    scopus 로고
    • Limited value of alarm features in the diagnosis of upper gastrointestinal malignancy: Systematic review and metaanalysis
    • Vakil N, Moayyedi P, Fennerty MB, Talley NJ. Limited value of alarm features in the diagnosis of upper gastrointestinal malignancy: systematic review and metaanalysis. Gastroenterology 2006;131:390-401.
    • (2006) Gastroenterology , vol.131 , pp. 390-401
    • Vakil, N.1    Moayyedi, P.2    Fennerty, M.B.3    Talley, N.J.4
  • 73
    • 13744261420 scopus 로고    scopus 로고
    • Updated guidelines for the diagnosis and treatment of gastroesophageal reflux disease
    • DeVault KR, Castell DO. Updated guidelines for the diagnosis and treatment of gastroesophageal reflux disease. Am J Gastroenterol 2005;100:190-200.
    • (2005) Am J Gastroenterol , vol.100 , pp. 190-200
    • DeVault, K.R.1    Castell, D.O.2
  • 74
    • 28144454058 scopus 로고    scopus 로고
    • Symptom association analysis in ambulatory gastroesophageal reflux monitoring
    • Bredenoord AJ, Weusten BL, Smout AJ. Symptom association analysis in ambulatory gastroesophageal reflux monitoring. Gut 2005;54:1810-7.
    • (2005) Gut , vol.54 , pp. 1810-1817
    • Bredenoord, A.J.1    Weusten, B.L.2    Smout, A.J.3
  • 75
    • 33748369873 scopus 로고    scopus 로고
    • Esophageal pH-impedance monitoring and symptom analysis in GERD: A study in patients off and on therapy
    • Zerbib F, Roman S, Ropert A, des Varannes SB, Pouderoux P, Chaput U et al. Esophageal pH-impedance monitoring and symptom analysis in GERD: a study in patients off and on therapy. Am J Gastroenterol 2006;101:1956-63.
    • (2006) Am J Gastroenterol , vol.101 , pp. 1956-1963
    • Zerbib, F.1    Roman, S.2    Ropert, A.3    des Varannes, S.B.4    Pouderoux, P.5    Chaput, U.6
  • 76
    • 53149102038 scopus 로고    scopus 로고
    • Esophageal pH-impedance monitoring in patients with therapy-resistant reflux symptoms: "on" or "off" proton pump inhibitor?
    • Hemmink GJ, Bredenoord AJ, Weusten BL, Monkelbaan JF, Timmer R, Smout AJ. Esophageal pH-impedance monitoring in patients with therapy-resistant reflux symptoms: "on" or "off" proton pump inhibitor? Am J Gastroenterol 2008;103:2446-53.
    • (2008) Am J Gastroenterol , vol.103 , pp. 2446-2453
    • Hemmink, G.J.1    Bredenoord, A.J.2    Weusten, B.L.3    Monkelbaan, J.F.4    Timmer, R.5    Smout, A.J.6
  • 77
    • 0032977314 scopus 로고    scopus 로고
    • Quality of life in patients with heartburn but without esophagitis: Effects of treatment with omeprazole
    • Havelund T, Lind T, Wiklund I, Glise H, Hernqvist H, Lauritsen K et al. Quality of life in patients with heartburn but without esophagitis: effects of treatment with omeprazole. Am J Gastroenterol 1999;94:1782-9.
    • (1999) Am J Gastroenterol , vol.94 , pp. 1782-1789
    • Havelund, T.1    Lind, T.2    Wiklund, I.3    Glise, H.4    Hernqvist, H.5    Lauritsen, K.6
  • 78
    • 21844455031 scopus 로고    scopus 로고
    • Medical treatments for the maintenance therapy of reflux oesophagitis and endoscopic negative reflux disease
    • CD003245
    • Donnellan C, Sharma N, Preston C, Moayyedi P. Medical treatments for the maintenance therapy of reflux oesophagitis and endoscopic negative reflux disease. Cochrane Database Syst Rev 2005;CD003245.
    • (2005) Cochrane Database Syst Rev
    • Donnellan, C.1    Sharma, N.2    Preston, C.3    Moayyedi, P.4
  • 79
    • 22844451154 scopus 로고    scopus 로고
    • Systematic review: Proton-pump inhibitor failure in gastro-oesophageal reflux disease where next?
    • Fass R, Shapiro M, Dekel R, Sewell J. Systematic review: proton-pump inhibitor failure in gastro-oesophageal reflux disease where next? Aliment Pharmacol Ther 2005;22:79-94.
    • (2005) Aliment Pharmacol Ther , vol.22 , pp. 79-94
    • Fass, R.1    Shapiro, M.2    Dekel, R.3    Sewell, J.4
  • 80
    • 0034995918 scopus 로고    scopus 로고
    • Simultaneous intraesophageal impedance and pH measurement of acid and non-acid gastroesophageal reflux: Effect of omeprazole
    • Vela MF, Camacho-Lobato L, Srinivasan R, Tutuian R, Katz PO, Castell DO. Simultaneous intraesophageal impedance and pH measurement of acid and non-acid gastroesophageal reflux: effect of omeprazole. Gastroenterology 2001;120:1599-606.
    • (2001) Gastroenterology , vol.120 , pp. 1599-1606
    • Vela, M.F.1    Camacho-Lobato, L.2    Srinivasan, R.3    Tutuian, R.4    Katz, P.O.5    Castell, D.O.6
  • 82
    • 0034650261 scopus 로고    scopus 로고
    • Laparoscopic or conventional Nissen fundoplication for gastro-oesophageal reflux disease: Randomised clinical trial. The Netherlands Antireflux Surgery Study Group
    • Bais JE, Bartelsman JF, Bonjer HJ, Cuesta MA, Go PM, Klinkenberg-Knol EC et al. Laparoscopic or conventional Nissen fundoplication for gastro-oesophageal reflux disease: randomised clinical trial. The Netherlands Antireflux Surgery Study Group. Lancet 2000;355:170-4.
    • (2000) Lancet , vol.355 , pp. 170-174
    • Bais, J.E.1    Bartelsman, J.F.2    Bonjer, H.J.3    Cuesta, M.A.4    Go, P.M.5    Klinkenberg-Knol, E.C.6
  • 83
    • 0035832264 scopus 로고    scopus 로고
    • Long-term outcome of medical and surgical therapies for gastroesophageal reflux disease: Follow-up of a randomized controlled trial
    • Spechler SJ, Lee E, Ahnen D, Goyal RK, Hirano I, Ramirez F et al. Long-term outcome of medical and surgical therapies for gastroesophageal reflux disease: follow-up of a randomized controlled trial. JAMA 2001;285:2331-8.
    • (2001) JAMA , vol.285 , pp. 2331-2338
    • Spechler, S.J.1    Lee, E.2    Ahnen, D.3    Goyal, R.K.4    Hirano, I.5    Ramirez, F.6
  • 84
    • 0033958395 scopus 로고    scopus 로고
    • Control of transient lower esophageal sphincter relaxations and reflux by the GABA(B) agonist baclofen in normal subjects
    • Lidums I, Lehmann A, Checklin H, Dent J, Holloway RH. Control of transient lower esophageal sphincter relaxations and reflux by the GABA(B) agonist baclofen in normal subjects. Gastroenterology 2000;118:7-13.
    • (2000) Gastroenterology , vol.118 , pp. 7-13
    • Lidums, I.1    Lehmann, A.2    Checklin, H.3    Dent, J.4    Holloway, R.H.5
  • 85
    • 0242500869 scopus 로고    scopus 로고
    • Effect of acute and chronic administration of the GABA B agonist baclofen on 24 hour pH metry and symptoms in control subjects and in patients with gastro-oesophageal reflux disease
    • Ciccaglione AF, Marzio L. Effect of acute and chronic administration of the GABA B agonist baclofen on 24 hour pH metry and symptoms in control subjects and in patients with gastro-oesophageal reflux disease. Gut 2003;52:464-70.
    • (2003) Gut , vol.52 , pp. 464-470
    • Ciccaglione, A.F.1    Marzio, L.2
  • 86
    • 47749121763 scopus 로고    scopus 로고
    • Synthesis and pharmacological evaluation of novel gamma-aminobutyric acid type B (GABAB) receptor agonists as gastroesophageal reflux inhibitors
    • Alstermark C, Amin K, Dinn SR, Elebring T, Fjellstrom O, Fitzpatrick K et al. Synthesis and pharmacological evaluation of novel gamma-aminobutyric acid type B (GABAB) receptor agonists as gastroesophageal reflux inhibitors. J Med Chem 2008;51:4315-20.
    • (2008) J Med Chem , vol.51 , pp. 4315-4320
    • Alstermark, C.1    Amin, K.2    Dinn, S.R.3    Elebring, T.4    Fjellstrom, O.5    Fitzpatrick, K.6
  • 87
    • 24144487047 scopus 로고    scopus 로고
    • Inhibition of transient lower esophageal sphincter relaxation and gastroesophageal reflux by metabotropic glutamate receptor ligands
    • Frisby CL, Mattsson JP, Jensen JM, Lehmann A, Dent J, Blackshaw LA. Inhibition of transient lower esophageal sphincter relaxation and gastroesophageal reflux by metabotropic glutamate receptor ligands. Gastroenterology 2005;129:995-1004.
    • (2005) Gastroenterology , vol.129 , pp. 995-1004
    • Frisby, C.L.1    Mattsson, J.P.2    Jensen, J.M.3    Lehmann, A.4    Dent, J.5    Blackshaw, L.A.6
  • 88
    • 27744549064 scopus 로고    scopus 로고
    • Transient lower esophageal sphincter relaxations in dogs are inhibited by a metabotropic glutamate receptor 5 antagonist
    • Jensen J, Lehmann A, Uvebrant A, Carlsson A, Jerndal G, Nilsson K et al. Transient lower esophageal sphincter relaxations in dogs are inhibited by a metabotropic glutamate receptor 5 antagonist. Eur J Pharmacol 2005;519:154-7.
    • (2005) Eur J Pharmacol , vol.519 , pp. 154-157
    • Jensen, J.1    Lehmann, A.2    Uvebrant, A.3    Carlsson, A.4    Jerndal, G.5    Nilsson, K.6
  • 89
    • 0036124689 scopus 로고    scopus 로고
    • Is glutamate involved in transient lower esophageal sphincter relaxations?
    • Hirsch DP, Tytgat GN, Boeckxstaens GE. Is glutamate involved in transient lower esophageal sphincter relaxations? Dig Dis Sci 2002;47:661-6.
    • (2002) Dig Dis Sci , vol.47 , pp. 661-666
    • Hirsch, D.P.1    Tytgat, G.N.2    Boeckxstaens, G.E.3
  • 90
    • 75749106878 scopus 로고    scopus 로고
    • A single-blind, placebo-controlled, proof of concept study of the effect of the MGLUR5 negative allosteric modulator, ADX10059, on 24h oesophageal pH and clinical symptoms, in patients with gastroesophageal reflux disease
    • Keywood C, Wakefield M. A single-blind, placebo-controlled, proof of concept study of the effect of the MGLUR5 negative allosteric modulator, ADX10059, on 24h oesophageal pH and clinical symptoms, in patients with gastroesophageal reflux disease. Neurogastroenterol Motil 2008;20:20.
    • (2008) Neurogastroenterol Motil , vol.20 , pp. 20
    • Keywood, C.1    Wakefield, M.2
  • 92
    • 0141757445 scopus 로고    scopus 로고
    • Effect of the GABA(B) agonist baclofen in patients with symptoms and duodeno-gastro-oesophageal reflux refractory to proton pump inhibitors
    • Koek GH, Sifrim D, Lerut T, Janssens J, Tack J. Effect of the GABA(B) agonist baclofen in patients with symptoms and duodeno-gastro-oesophageal reflux refractory to proton pump inhibitors. Gut 2003;52:1397-402.
    • (2003) Gut , vol.52 , pp. 1397-1402
    • Koek, G.H.1    Sifrim, D.2    Lerut, T.3    Janssens, J.4    Tack, J.5
  • 93
    • 67650461959 scopus 로고    scopus 로고
    • Beaumont H, Boeckxstaens GE. Does the presence of a hiatal hernia affects the efficacy of the reflux inhibitor baclofen during add-on therapy? Am J Gastrienterology 2009. In press.
    • Beaumont H, Boeckxstaens GE. Does the presence of a hiatal hernia affects the efficacy of the reflux inhibitor baclofen during add-on therapy? Am J Gastrienterology 2009. In press.
  • 94
    • 36849058087 scopus 로고    scopus 로고
    • Review article: The endoscopic treatment of gastrooesophageal reflux disease
    • Schwartz MP, Smout AJ. Review article: the endoscopic treatment of gastrooesophageal reflux disease. Aliment Pharmacol Ther 2007;26(Suppl 2):1-6.
    • (2007) Aliment Pharmacol Ther , vol.26 , Issue.SUPPL. 2 , pp. 1-6
    • Schwartz, M.P.1    Smout, A.J.2
  • 95
    • 0042471691 scopus 로고    scopus 로고
    • Improvement of gastroesophageal reflux symptoms after radiofrequency energy: A randomized, sham-controlled trial
    • Corley DA, Katz P, Wo JM, Stefan A, Patti M, Rothstein R et al. Improvement of gastroesophageal reflux symptoms after radiofrequency energy: a randomized, sham-controlled trial. Gastroenterology 2003;125:668-76.
    • (2003) Gastroenterology , vol.125 , pp. 668-676
    • Corley, D.A.1    Katz, P.2    Wo, J.M.3    Stefan, A.4    Patti, M.5    Rothstein, R.6
  • 96
    • 34547851721 scopus 로고    scopus 로고
    • Influence of radiofrequency energy delivery at the gastroesophageal junction (the Stretta procedure) on symptoms, acid exposure, and esophageal sensitivity to acid perfusion in gastroesophagal reflux disease
    • Arts J, Sifrim D, Rutgeerts P, Lerut A, Janssens J, Tack J. Influence of radiofrequency energy delivery at the gastroesophageal junction (the Stretta procedure) on symptoms, acid exposure, and esophageal sensitivity to acid perfusion in gastroesophagal reflux disease. Dig Dis Sci 2007;52:2170-7.
    • (2007) Dig Dis Sci , vol.52 , pp. 2170-2177
    • Arts, J.1    Sifrim, D.2    Rutgeerts, P.3    Lerut, A.4    Janssens, J.5    Tack, J.6
  • 97
    • 57049092183 scopus 로고    scopus 로고
    • Magnetic augmentation of the lower esophageal sphincter: Results of a feasibility clinical trial
    • Bonavina L, Saino GI, Bona D, Lipham J, Ganz RA, Dunn D et al. Magnetic augmentation of the lower esophageal sphincter: results of a feasibility clinical trial. J Gastrointest Surg 2008;12:2133-40.
    • (2008) J Gastrointest Surg , vol.12 , pp. 2133-2140
    • Bonavina, L.1    Saino, G.I.2    Bona, D.3    Lipham, J.4    Ganz, R.A.5    Dunn, D.6


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