Transplacental congenital human herpesvirus 6 infection caused by maternal chromosomally integrated virus

Journal of Infectious Diseases

Volumn 201, Issue 4, 2010, Pages 505-507

  Hall, Caroline Bresse ^a,b   Cassrta, Mary T ^a   Schnabel, Kenneth C ^a   Shelley, Lynns M ^a   Carnahan, Jennifer A ^a   Marino, Andrea S ^a   Yoo, Christina ^a   Lofthus, Geraldine K ^b  

^a Departments of Pediatrics   (United States)

^b UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

VIRUS DNA;

ARTICLE; BLOOD SAMPLING; CHROMOSOME; CLINICAL ARTICLE; DNA VIRUS; FEMALE; FETOMATERNAL TRANSFUSION; HAIR; HERPES VIRUS INFECTION; HUMAN; HUMAN HERPESVIRUS 6; INFANT; MOTHER; PLACENTAL TRANSFER; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SALIVA; UMBILICAL CORD BLOOD; URINE; VIRUS LOAD; VIRUS REPLICATION;

CHILD, PRESCHOOL; FEMALE; HERPESVIRUS 6, HUMAN; HUMANS; INFANT; INFECTIOUS DISEASE TRANSMISSION, VERTICAL; MATERNAL-FETAL EXCHANGE; POLYMERASE CHAIN REACTION; PREGNANCY; PREGNANCY COMPLICATIONS, INFECTIOUS; ROSEOLOVIRUS INFECTIONS; VIRUS INTEGRATION;

EID: 75749131964     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1086/650495     Document Type: Article

References (13)

1. Hall C, Caserta M, Schnabel K, et al. Congenital infections with human herpesviruses 6 and 7. J Pediatr 2004; 145:472-477.
2. Hall C, Caserta M, Schnabel K, et al. Chromosomal integration of human herpesvirus 6 is the major mode of congenital human her-pesvirus 6 infection. Pediatrics 2008; 122:513-520.
3. 3.BoppanaS,PassR,BrittW.Virus-specificantibodyresponsesinmoth- ersandtheirnewborninfantswithasymptomaticcongenitalcyto-megalovirusinfections. JInfectDis1993;167:72-77.(Pubitemid23002839)
4. Clark D, Nacheva E, Leong H, et al. Transmission of integrated human herpesvirus 6 through stem cell transplantation: implications for lab-oratory diagnosis. J Infect Dis 2006; 193:912-916.
5. Ward K, Leong H, Nacheva E, et al. Human herpesvirus 6 chromosom-al integration in immunocompetent patients results in high levels of vi-ral DNA in blood, sera, and hair follicles. J Clin Microbiol 2006; 44: 1571-1574.
6. 6. Caserta M, McDermott M, Dewhurst S, et al. Human herpesvirus 6 (HHV6) DNA persistence and reactivation in healthy children. J Pe-diatr 2004; 145:478-484. (Pubitemid 39345983)
7. Qiagen, Inc. Technical Information and Guidelines. Nucleic acids and proteins: mammalian cells and tissues, 2007. http://wwwl.qiagen.com/resources/ info/. Accessed January 2009.
8. 8.ClarkD,Ait-KhaledM,WheelerA,etal. Quantificationofhumanherpesvirus6inimmunocompetentpersonsandpost- mortemtissuesfromAIDSpatientsbyPCR.JGenVirol1996;77:2271-2275. (Pubitemid26316098)
9. Jefferies WM, Turner J, Lobo M, Gwaltney JM, Jr. Low plasma levels of adrenocorticotropic hormone in patients with acute influenza. Clin Infect Dis 1998;26:708-710.
10. 10.HallC,LongC,SchnabelK,etal.Humanherpesvirus-6infectioninchildren: aprospectivestudyofcomplicationsandreactivation.NEnglJMed1994;331:432-438. (Pubitemid24984709)
11. Caserta M, Hall C, Schnabel K, Lofthus G, McDermott M. Human herpesvirus (HHV)-6 and HHV-7 infections in pregnant women. J Infect Dis 2007; 196:1296-1303.
12. Lo YM, Lau TK, Chan LY, Leung TN, Chang AM. Quantitative analysis of the bidirectional fetomaternal transfer of nucleated cells and plasma DNA. Clin Chem 2000;46:1301-1309.
13. 13.HallC,CasertaM,SchnabelK,etal.Persistenceofhumanherpesvirus6according- siteandvariant:possiblegreaterneurotropismofvariantA.ClinInfectDis1998;26: 132-137.(Pubitemid28068166)