Upregulation of fractalkine and its receptor, CX3CR1, is associated with coronary plaque rupture in patients with unstable angina pectoris

Circulation Journal

Volumn 74, Issue 2, 2010, Pages 337-345

  Ikejima, Hideyuki ^a   Imanishi, Toshio ^a   Tsujioka, Hiroto ^a   Kashiwagi, Manabu ^a   Kuroi, Akio ^a   Tanimoto, Takashi ^a   Kitabata, Hironori ^a   Ishibashi, Kohei ^a   Komukai, Kenichi ^a   Takeshita, Tatsuya ^a   Akasaka, Takashi ^a  

^a WAKAYAMA MEDICAL UNIVERSITY   (Japan)

Author keywords

Acute coronary syndrome; Chemokine; Coronary plaque rupture; Optical coherence tomography

Indexed keywords

ACETYLSALICYLIC ACID; ANTILIPEMIC AGENT; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CD14 ANTIGEN; CD16 ANTIGEN; CD3 ANTIGEN; CHEMOKINE RECEPTOR CX3CR1; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; FRACTALKINE;

ADULT; ANGIOCARDIOGRAPHY; ARTICLE; ATHEROSCLEROTIC PLAQUE; CD3+ T LYMPHOCYTE; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FLOW CYTOMETRY; HUMAN; MALE; MONOCYTE; NATURAL KILLER CELL; OPTICAL COHERENCE TOMOGRAPHY; PROTEIN BLOOD LEVEL; RECEPTOR UPREGULATION; STABLE ANGINA PECTORIS; T LYMPHOCYTE; UNSTABLE ANGINA PECTORIS;

AGED; ANGINA, UNSTABLE; ANTIGENS, CD14; ANTIGENS, CD3; BIOLOGICAL MARKERS; CHEMOKINE CX3CL1; CORONARY ANGIOGRAPHY; CORONARY ARTERY DISEASE; DISEASE PROGRESSION; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FLOW CYTOMETRY; HUMANS; LOGISTIC MODELS; LYMPHOCYTES; MALE; MIDDLE AGED; MONOCYTES; ODDS RATIO; RECEPTORS, CHEMOKINE; RECEPTORS, IGG; RISK ASSESSMENT; RISK FACTORS; RUPTURE; TOMOGRAPHY, OPTICAL COHERENCE; UP-REGULATION;

EID: 75749111011     PISSN: 13469843     EISSN: 13474820     Source Type: Journal    
DOI: 10.1253/circj.CJ-09-0484     Document Type: Article

References (34)

1. Fuster V, Badimon L, Badimon JJ, Chesebro JH. The pathogenesis of coronary artery disease and acute coronary syndrome (2). N Engl J Med 1992; 306: 310-318.
2. Buja LM, Willerson JT. Role of inflammation in coronary plaque disruption. Circulation 1994; 89: 503-505.
3. Libby P. Molecular bases of the acute coronary syndromes. Circulation 1995; 91: 2844-2850.
4. Gallis Z, Sukhova S, Lark MW, Libby P. Increased expression of matrix metalloproteinases and matrix degrading activity in vulnerable regions of human atherosclerotic plaques. J Clin Invest 1994; 94: 2493-2503.
5. Moreno PR, Bernardi VH, Lopez-Cuellar I, Murcia AM, Palacios IF, Gold HK, et al. Macrophages, smooth muscle cells, and tissue factor in unstable angina: Implication for cell-mediated thrombogenicity in acute coronary syndrome. Circulation 1996; 94: 3090-3097.
6. Charo IF, Taubman MB. Chemokine in the pathogenesis of vascular disease. Circ Res 2004; 95: 858-866.
7. Damas JK, Boullier A, Waehre T, Smith C, Sandberg WJ, Green S, et al. Expression of fractalkine (CX3CL1) and its receptor, CX3CR1, is elevated in coronary artery disease and is reduced during statin therapy. Arterioscler Thromb Vasc Biol 2005; 25: 2567-2572.
8. + monocytes. J Exp Med 2003; 197: 1701-1707.
9. Belperio JA, Ardehali A. Chemokines and transplant vasculopathy. Circ Res 2008; 103: 454-466.
10. Jang IK, Bouma BE, Kang DH, Park SJ, Seung KB, Choi KB, et al. Visualization of coronary atherosclerotic plaques in patients using optical coherence tomography comparison with intravascular ultrasound. J Am Coll Cardiol 2002; 39: 604-609.
11. Kume T, Akasaka T, Kawamoto T, Watanabe N, Toyota E, Neishi Y, et al. Assessment of coronary artery plaque by optical coherence tomography. Am J Cardiol 2006; 97: 1172-1175.
12. Jang IK, Tearney GJ, MacNeil B, Takano M, Moselewski F, Iftima N, et al. In vivo characterization of coronary atherosclerotic plaque by use of optical coherence tomography. Circulation 2005; 111: 1551-1555.
13. Brezinski ME, Tearney GJ, Bouma BE, Izatt JA, Hee MR, Swanson EA, et al. Optical coherence tomography for optical biopsy: Properties and demonstration of vascular pathology. Circulation 1996; 93: 1206-1213.
14. Kubo T, Imanishi T, Takarada S, Kuroi A, Ueno S, Yamano T, et al. Assessment of culprit lesion morphology in acute myocardial infarction. J Am Coll Cardiol 2007; 50: 933-939.
15. Tanimoto T, Imanishi T, Tanaka A, Yamano T, Kitabata H, Takarada S, et al. Various types of plaque disruption in culprit coronary artery visualized by optical coherence tomography in a patient with unstable angina. Circ J 2009; 73: 187-189.
16. Ambrose JA, Winters SL, Arora RR, Haft JI, Goldstein J, Rentrop KP, et al. Coronary angiographic morphology in myocardial infarction: A link between the pathogenesis of unstable angina and myocardial infarction. J Am Coll Cardiol 1985; 6: 1233-1238.
17. Ambrose JA, Winters SL, Stern A, Teichholz LE, Gorlin R, Fuster V. Angiographic morphology and the pathogenesis of unstable angina pectoris. J Am Coll Cardiol 1985; 5: 609-616.
18. Kataiwa H, Tanaka A, Kitabata H, Imanishi T, Akasaka T. Safety and usefulness of non-occlusion image acquisition technique for optical coherence tomography. Circ J 2008; 72: 1536-1537.
19. + blood monocytes: Their role in infection and inflammation. J Leukoc Biol 2007; 81: 584-592.
20. Sano T, Tanaka A, Namba M, Nishibori Y, Nishida Y, Kawarabayashi T, et al. C-reactive protein and lesion morphology with acute myocardial infarction. Circulation 2003; 108: 282-285.
21. Hong MK, Mintz GS, Lee CW, Kim YH, Lee SW, Song JM, et al. Comparison of coronary plaque rupture between stable angina and acute myocardial infarction: A three-vessel intravascular ultrasound study in 235 patients. Circulation 2004; 110: 928-933.
22. Date T, Yamashita T, Sekiguchi A, Iwasaki YK, Aizawa T, Yamane T, et al. Infiltration of macrophage through the atrial endocardium of inflammation-induced rats: Contribution of fractalkine. Circ J 2009; 73: 932-935.
23. Lesnik P, Haskel CA, Charo IF. Decreased atherosclerosis in CX3CR1-/- mice reveals a role for fractalkine in atherosclerosis. J Clin Invest 2003; 111: 333-340.
24. Combadiere C, Potteaux S, Gao JL, Esposito B, Casanova S, Lee EJ, et al. Decreased atherosclerotic lesion formation in CX3CR1/apolipoprotein E double knockout mice. Circulation 2003; 107: 1009-1016.
25. Moatti D, Faure S, Fumeron F, Amara MEW, Seknadji P, McDermott DH, et al. Polymorphism in the fractalkine receptor CX3CR1 as a genetic risk factor in the coronary artery disease. Blood 2001; 97: 1925-1928.
26. MacDermott DH, Halcox JPJ, Schenke WH, Waclawiw MA, Merrell MN, Epstein N, et al. Association between polymorphism in the chemokine receptor CX3CR1 and coronary vascular endothelial dysfunction and atherosclerosis. Circ Res 2001; 89: 401-407.
27. Ross R. Atherosclerosis is an inflammatory disease. Am Heart J 1999; 138: S419-S420.
28. Shah PK. Plaque disruption and thrombosis: Potential role of inflammation and infection. Cardiol Clin 1999; 17: 271-281.
29. Hansson GK. Inflammation, atherosclerosis, and coronary artery disease. N Engl J Med 2005; 352: 1685-1695.
30. Moreno PR, Falk E, Palacios IF, Newell JB, Fuster V, Fallon JT. Macrophage infiltration in acute coronary syndromes: Implications for plaque rupture. Circulation 1994; 90: 775-778.
31. Liuzzo G, Vallejo AN, Kopecky SL, Frye R, Holmes DR, Goronzy JJ, et al. Molecular fingerprint of interferon-γ signaling in unstable angina. Circulation 2001; 103: 1509-1514.
32. Caligiuri G, Paulson G, Nicoletti A, Maseri A, Hansson GK. Evidence for antigen-driven T cell response in unstable angina. Circulation 2000; 102: 1114-1119.
33. Clerc G, Rouz PM. Lymphocyte subsets in severe atherosclerosis before revascularization. Ann Intern Med 1997; 126: 1004-1005.
34. Millonig G, Malcom GT, Wick G. Early inflammatory-immunological lesions in juvenile atherosclerosis from the Pathobiological Determinants of Atherosclerosis in Youth (PDAY) study. Atherosclerosis 2002; 160: 441-448.