The prostate growth stimulation by progesterone is due to androgenic products and progesterone receptor-mediated mechanisms

Pharmazie

Volumn 64, Issue 9, 2009, Pages 587-589

  Nishino, Tsuyuki ^a   Ishibashi, K ^b   Hirtreiter, C ^c   Nishino, Y ^d  

^a Dr Knoell Consult GmbH   (Germany)

^b ELI LILLY AND COMPANY   (United States)

^c UNIVERSITY OF REGENSBURG   (Germany)

^d BAYER PHARMA AG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANDROGEN; ANDROSTANOLONE; ANTIANDROGEN; ANTIESTROGEN; ANTIGESTAGEN; ESTRADIOL; FLUTAMIDE; FULVESTRANT; ONAPRISTONE; PROGESTERONE; PROGESTERONE RECEPTOR; TESTOSTERONE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; DRUG MECHANISM; GROWTH STIMULATION; HORMONE DEPENDENCE; IMMUNOHISTOCHEMISTRY; MALE; NONHUMAN; ORCHIECTOMY; ORGAN WEIGHT; PROSTATE TUMOR; PROTEIN EXPRESSION; RADIOIMMUNOLOGY; RAT; TESTOSTERONE BLOOD LEVEL; TREATMENT DURATION; TUMOR GROWTH; TUMOR LOCALIZATION; WISTAR RAT;

ANDROGENS; ANIMALS; BODY WEIGHT; DIHYDROTESTOSTERONE; DOSE-RESPONSE RELATIONSHIP, DRUG; ESTRADIOL; GONANES; HORMONE ANTAGONISTS; MALE; ORCHIECTOMY; ORGAN SIZE; PROGESTERONE; PROSTATE; RATS; RATS, WISTAR; RECEPTORS, PROGESTERONE; STIMULATION, CHEMICAL;

EID: 75749109836     PISSN: 00317144     EISSN: None     Source Type: Journal    
DOI: 10.1691/ph.2009.9583     Document Type: Article

References (6)

1. Belis JA, Lizza EF, Tarry WF (1984) Progesterone receptors in the prostate. Prog Clin Biol Res 145: 345-361.
2. Ganjam VK, Amann RP (1976) Steroids in fluids and sperm entering and leaving the bovine epididymis, epididymal tissue, and accessory sex gland secretions. Endocrinology 99: 1618-1630.
3. Jones LA, Connell CJ (1982) Evidence for progesterone receptors in the epididymis of the prepubertal dog. J Androl 3: 16-17 (1982)
4. Kumar VL, Wadhwa SN, Kumar V, Farooq A (1990) Androgen, estrogen, and progesterone receptor contents and serum hormone profiles in patients with benign hypertrophy and carcinoma of the prostate. J Surg Oncol 44: 122-128.
5. Mobbs BG, Johnson IE (1991) Suppression of the growth of the androgenin-sensitive R3327 HI rat prostatic carcinoma by combined estrogen and antiprogestin treatment. J Steroid Biochem Molec Biol 39: 713-722.
6. Price D, Mann T, Lutwak-Mann C (1955) The stimulating effect of female hormones on the metabolic activity and histological structure of male rat accessory reproductive glands. Anat Rec 122: 363-379.