The role of serum ferritin, pro-brain natriuretic peptide and homocysteine levels in determining ischaemic stroke subtype, severity and mortality

Hong Kong Journal of Emergency Medicine

Volumn 17, Issue 1, 2010, Pages 13-21

  Ustundag M ^b   Orak, M ^b   Guloglu C ^b   Ozturk E ^b   Tamam, Y ^a   Kale, E ^a  

^a DICLE UNIVERSITY   (Turkey)

^b Biochemistry Department ^*

Author keywords

Brain natriuretic peptide; Ferritins; Homocysteine; Mortality; Stroke

Indexed keywords

BRAIN NATRIURETIC PEPTIDE; FERRITIN; HOMOCYSTEINE;

AGED; AMINO ACID BLOOD LEVEL; ARTICLE; CEREBROVASCULAR ACCIDENT; CIRCULATION; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; DISEASE SEVERITY; EMERGENCY WARD; FEMALE; FERRITIN BLOOD LEVEL; GROUPS BY AGE; HUMAN; MAJOR CLINICAL STUDY; MALE; MORTALITY; NATIONAL INSTITUTES OF HEALTH STROKE SCALE; NUCLEAR MAGNETIC RESONANCE IMAGING; PREDICTION; PROTEIN BLOOD LEVEL; SEX DIFFERENCE;

EID: 75749107836     PISSN: 10249079     EISSN: None     Source Type: Journal    
DOI: 10.1177/102490791001700103     Document Type: Article

References (26)

1. Hankey GJ, Sudlow CL, Dunbabin DW. Thienopyridine derivatives (ticlopidine, clopidogrel) versus aspirin for preventing stroke and other serious vascular events in high vascular risk patients. Cochrane Database Syst Rev 2000;1:CD001246.
2. Diener HC, Cunha L, Forbes C, Sivenius J, Smets P, Lowenthal A. European Stroke Prevention Study. 2. Dipyridamole and acetylsalicylic acid in the secondary prevention of stroke. J Neurol Sci 1996;143(1-2):1-13.
3. Lynch JR, Blessing R, White WD, Grocott HP, Newman MF, Laskowitz DT. Novel diagnostic test for acute stroke. Stroke 2004;35(1):57-63.
4. Nakagawa K, Yamaguchi T, Seida M, Yamada S, Imae S, Tanaka Y, et al. Plasma concentrations of brain natriuretic peptide in patients with acute ischemic stroke. Cerebrovasc Dis 2005;19(3):157-64.
5. Iltumur K, Yavavli A, Apak I, Ariturk Z, Toprak N. Elevated plasma N-terminal pro-brain natriuretic peptide levels in acute ischemic stroke. Am Heart J 2006;151(5):1115-22. Erratum in: Am Heart J 2007;153(2):312.
6. Lindgren A, Brattstrom L, Norrving B, Hultberg B, Andersson A, Johansson BB. Plasma homocysteine in the acute and convalescent phases after stroke. Stroke 1995;26(5):795-800.
7. Armengou A, Davalos A, Fernandez-Real JM, Castillo J. Serum ferritin concentrations are not modified in the acute phase of ischemic stroke. Stroke 1998;29(1):258-60.
8. Johnson CJ, Kittner SJ, McCarter RJ, Sloan MA, Stern BJ, Buchholz D, et al. Interrater reliability of an etiologic classification of ischemic stroke. Stroke 1995;26(1):46-51.
9. Bamford J, Sandercock P, Dennis M, Burn J, Warlow C. Classification and natural history of clinically identifiable subtypes of cerebral infarction. Lancet 1991;337(8756):1521-6.
10. Tatu L, Moulin T, Bogousslavsky J, Duvernoy H. Arterial territories of human brain: brainstem and cerebellum. Neurology 1996;47(5):1125-35.
11. Adams HP Jr, Bendixen BH, Kappelle LJ, Biller J, Love BB, Gordon DL, et al. Classification of subtype of acute ischemic stroke. Definitions for use in a multicenter clinical trial. TOAST. Trial of Org 10172 in Acute Stroke Treatment. Stroke 1993;24(1):35-41.
12. Baird AE, Dambrosia J, Janket S, Eichbaum Q, Chaves C, Silver B, et al. A three-item scale for the early prediction of stroke recovery. Lancet 2001;357(9274):2095-9.
13. Hoogeveen EK, Kostense PJ, Jakobs C, Dekker JM, Nijpels G, Heine RJ, et al. Hyperhomocysteinemia increases risk of death, especially in type 2 diabetes: 5-year follow-up of the Hoorn Study. Circulation 2000;101(13):1506-11.
14. Spencer CG, Martin SC, Felmeden DC, Blann AD, Beevers GD, Lip GY. Relationship of homocysteine to markers of platelet and endothelial activation in 'high risk' hypertensives: a substudy of the Anglo-Scandinavian Cardiac Outcomes Trial. Int J Cardiol 2004;94(2-3):293-300.
15. Kang SS, Wong PW, Malinow MR. Hyperhomocysteinemia as a risk factor for occlusive vascular disease. Annu Rev Nutr 1992;12:279-98.
16. Kelly PJ, Rosand J, Kistler JP, Shih VE, Silveira S, Plomaritoglou A, et al. Homocysteine, MTHFR 677C - >T polymorphism, and risk of ischemic stroke: result of a meta-analysis. Neurology 2002;59(4):529-36.
17. McIlroy SP, Dynan KB, Lawson JT, Patterson CC, Passmore AP. Moderately elevated plasma homocysteine, methylenetetrahydrofolate reductase genotype, and risk for stroke, vascular dementia, and Alzheimer disease in Northern Ireland. Stroke 2002;33(10):2351-6.
18. Tan NC, Venketasubramanian N, Saw SM, Tjia HT. Hyperhomocysteinemia and risk of ischemic stroke among young Asian adults. Stroke 2002;33(8):1956-62.
19. Youssef MY, Mojiminiyi OA, Abdella NA. Plasma concentrations of C-reactive protein and total homocysteine in relation to the severity and risk factors for cerebrovascular disease. Transl Res 2007;150(3):158-63.
20. Etgen T, Baum H, Sander K, Sander D. Cardiac troponins and N-terminal pro-brain natriuretic peptide in acute ischemic stroke do not relate to clinical prognosis. Stroke 2005;36(2):270-5.
21. Dávalos A, Castillo J, Marrugat J, Fernandez-Real JM, Armengou A, Cacabelos P, et al. Body iron stores and early neurologic deterioration in acute cerebral infarction. Neurology 2000;54(8):1568-74.
22. Dávalos A, Fernandez-Real JM, Ricart W, Soler S, Molins A, Planas E, et al. Iron-related damage in acute ischemic stroke. Stroke 1994;25(8):1543-6. Erratum in: Stroke 1994;25(11):2300.
23. Christensen H, Boysen G, Johannesen HH, Christensen E, Bendtzen K. Deteriorating ischaemic stroke: cytokines, soluble cytokine receptors, ferritin, systemic blood pressure, body temperature, blood glucose, diabetes, stroke severity, and CT infarction-volume as predictors of deteriorating ischaemic stroke. J Neurol Sci 2002;201(1-2):1-7.
24. van der A DL, Grobbee DE, Roest M, Marx JJ, Voorbij HA, van der Schouw YT. Serum ferritin is a risk factor for stroke in postmenopausal women. Stroke 2005;36(8):1637-41.
25. Yip HK, Sun CK, Chang LT, Chen MC, Liou CW. Time course and prognostic value of plasma levels of N-terminal pro-brain natriuretic peptide in patients after ischemic stroke. Circ J 2006;70(4):447-52.
26. Di Angelantonio E, De Castro S, Toni D, Sacchetti ML, Biraschi F, Prencipe M, et al. Determinants of plasma levels of brain natriuretic peptide after acute ischemic stroke or TIA. J Neurol Sci 2007;260(1-2):139-42.