Within-subregion relationship between bone marrow lesions and subsequent cartilage loss in knee osteoarthritis

Arthritis Care and Research

Volumn 62, Issue 2, 2010, Pages 198-203

  Kothari, Ami ^a   Guermazi, Ali ^b   Chmiel, Joan S ^a   Dunlop, Dorothy ^a   Song, Jing ^a   Almagor, Orit ^a   Marshall, Meredith ^a   Cahue, September ^a   Prasad, Pottumarthi ^c   Sharma, Leena ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

^b BOSTON UNIVERSITY MEDICAL CENTER   (United States)

^c NORTHSHORE UNIVERSITY HEALTHSYSTEM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ARTICLE; BODY MASS; BONE CYST; BONE LESION; BONE MARROW DISEASE; CARTILAGE; CONTROLLED STUDY; FEMALE; FEMUR; HUMAN; KNEE OSTEOARTHRITIS; MAJOR CLINICAL STUDY; MALE; NUCLEAR MAGNETIC RESONANCE IMAGING; OSTEOLYSIS; TIBIA;

AGED; BONE CYSTS; BONE DISEASES; BONE MARROW DISEASES; CARTILAGE DISEASES; CARTILAGE, ARTICULAR; COHORT STUDIES; FEMALE; HUMANS; INCIDENCE; KNEE JOINT; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; OSTEOARTHRITIS, KNEE;

EID: 75749105054     PISSN: 21514658     EISSN: 15290131     Source Type: Journal    
DOI: 10.1002/acr.20068     Document Type: Article

References (14)

1. Burr DB. Subchondral bone in the pathogenesis of osteoarthritis: mechanical aspects. In: Brandt K, Doherty M, Lohmander LS, editors. Osteoarthritis. Oxford: Oxford University Press; 2003. p. 125-33.
2. Garrod AE. Rheumatoid arthritis, osteo-arthritis, arthritis deformans. In: Albutt TC, Rolleston HD, editors. A system of medicine. London: Macmillan; 1907. p. 3-43.
3. Roemer FW, Hunter DJ, Guermazi A. MRI-based semiquantitative assessment of subchondral bone marrow lesions in osteoarthritis research. Osteoarthritis Cartilage 2009;17:414-7.
4. Felson DT, McLaughlin S, Goggins J, LaValley M, Gale ME, Totterman S, et al. Bone marrow edema and its relation to progression of knee osteoarthritis. Ann Intern Med 2003;139:330-6.
5. Hunter DJ, Zhang Y, Niu J, Goggins J, Amin S, LaValley MP, et al. Increase in bone marrow lesions associated with cartilage loss: a longitudinal magnetic resonance imaging study of knee osteoarthritis. Arthritis Rheum 2006;54:1529-35.
6. Kijowski R, Stanton P, Fine J, De Smet A. Subchondral bone marrow edema in patients with degeneration of the articular cartilage of the knee joint. Radiology 2006;238:943-9.
7. Raynauld JP, Martel-Pelletier J, Berthiaume MJ, Abram F, Choquette D, Haraoui B, et al. Correlation between bone lesion changes and cartilage volume loss in patients with osteoarthritis of the knee as assessed by quantitative magnetic resonance imaging over a 24-month period. Ann Rheum Dis 2008;67:683-8.
8. Roemer FW, Guermazi A, Javaid MK, Lynch JA, Niu J, Zhang Y, et al. Change in MRI-detected subchondral bone marrow lesions is associated with cartilage loss: the MOST Study, a longitudinal multicenter study of knee osteoarthritis. Ann Rheum Dis 2009;68:1461-5.
9. Niu J, Hunter DJ, Felson DT, Guermazi A, Gale D, Zhang YQ. Evaluating the proximity of meniscal damage on risk of local cartilage loss using a matched case-control design [abstract]. Arthritis Rheum 2006;54 Suppl:S158.
10. Peterfy CG, Guermazi A, Zaim S, Tirman PF, Miaux Y, White D, et al. Whole-Organ Magnetic Resonance Imaging Score (WORMS) of the knee in osteoarthritis. Osteoarthritis Cartilage 2004;12:177-90.
11. Buckland-Wright CB. Protocols for precise radio-anatomical positioning of the tibiofemoral and patellofemoral compartments of the knee. Osteoarthritis Cartilage 1995;3 Suppl A:71-80.
12. Roemer FW, Guermazi A, Neogi T, Zhu Y, Zhang Y, Javaid MK, et al. The association of MRI-detected tibiofemoral subchondral bone marrow lesions with prevalent and incident subchondral bone attrition: the MOST Study [abstract]. Arthritis Rheum 2008;58 Suppl:S697.
13. Neogi T, Zhang Y, Niu J, Lynch J, Nevitt M, Lewis CE, et al. Cartilage loss occurs in the same subregions as subchondral bone attrition: the MOST Study [abstract]. Arthritis Rheum 2008;58 Suppl:S235.
14. Crema MD, Roemer FW, Marra MD, Niu J, Zhu Y, Lynch J, et al. MRI-detected bone marrow edema-like lesions are strongly associated with subchondral cysts in patients with or at risk for knee osteoarthritis: the MOST Study [abstract]. Osteoarthritis Cartilage 2008;16:S160.