Effects of hypercapnia, hypocapnia, and hyperoxemia on blood oxygenation level-dependent signal intensity determined by use of susceptibility-weighted magnetic resonance imaging in isoflurane-anesthetized dogs

American Journal of Veterinary Research

Volumn 71, Issue 1, 2010, Pages 24-32

  Rioja, Eva ^a   Kerr, Carolyn L ^a   McDonell, Wayne N ^a   Dobson, Howard ^a   Konyer, Norman B ^b   Poma, Roberto ^a   Noseworthy, Michael D ^b  

^a UNIVERSITY OF GUELPH   (Canada)

^b ST JOSEPH S HOSPITAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ATRACURIUM; ISOFLURANE; PROPOFOL;

ANALYSIS OF COVARIANCE; ANESTHESIA INDUCTION; ARTICLE; BLOOD OXYGENATION; CARBON DIOXIDE TENSION; CLINICAL ASSESSMENT; CONTROLLED STUDY; GRAY MATTER; HYPERCAPNIA; HYPEROXEMIA; HYPOCAPNIA; MALE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; OXYGEN TENSION; POST HOC ANALYSIS; RESPIRATORY FUNCTION DISORDER; SIGNAL TRANSDUCTION;

ANESTHETICS, INHALATION; ANIMALS; BRAIN; DOGS; HYPERCAPNIA; HYPEROXIA; HYPOCAPNIA; ISOFLURANE; MAGNETIC RESONANCE IMAGING; MALE; MONITORING, PHYSIOLOGIC; OXYGEN;

ANIMALIA; CANIS FAMILIARIS;

EID: 75749094775     PISSN: 00029645     EISSN: None     Source Type: Journal    
DOI: 10.2460/ajvr.71.1.24     Document Type: Article

References (42)

1. Chavhan GB. Miscellaneous MR techniques. In: Chavhan GB, ed. MRI made easy. Tunbridge Wells, Kent, England: Anshan Ltd, 2007,246-247.
2. Ogawa S, Lee TM, Kay AR, et al. Brain magnetic resonance imaging with contrast dependent on blood oxygenation. Proc Natl Acad Sci USA 1990;87:9868-9872.
3. Buxton RB, Frank LR. A model for the coupling between cerebral blood flow and oxygen metabolism during neural stimulation. J Cereb Blood Flow Metab 1997;17:64-72.
4. Jezzard P, Ramsey NE Functional MRI. In: Tofts P, ed. Quantitative MRI of the brain. John Wiley & Sons Ltd, 2003;413-453.
5. Davis TL, Kwong KK, Weisskoff RM, et al. Calibrated functional MRI: mapping the dynamics of oxidative metabolism. Proc Natl Acad Sci USA 1998;95:1834-1839.
6. McDonell WN, Kerr CL. Respiratory system. In: Tranquilli WJ, Thurmon JC, Grimm KA, eds. Lumb and Jones' veterinary anesthesia and analgesia. 4th ed. Blackwell Publishing Ltd, 2007;117-151.
7. Posse S, Kemna LJ, Elghahwagi B, et al. Effect of graded hypo-and hypercapnia on fMRI contrast in visual cortex: quantification of T(*)(2) changes by multiecho EPI. Magn Reson Med 2001;46:264-271.
8. Posse S, Olthoff U, Weckesser M, et al. Regional dynamic signal changes during controlled hyperventilation assessed with blood oxygen level-dependent functional MR imaging. AJNR Am J Neuroradiol 1997;18:1763-1770.
9. Losen C, Peller M, Schneider P, et al. Oxygen-enhanced MRI of the brain. Magn Reson Med 2002;48:271-277.
10. Prisman E, Slessarev M, Han J, et al. Comparison of the effects of independently-controlled end-tidal PCO(2) and PO(2) on blood oxygen level-dependent (BOLD) MRI. J Magn Reson Imaging 2008;27:185-191.
11. Brevard ME, Duong TQ, KingJA, et al. Changes in MRI signal intensity during hypercapnic challenge under conscious and anesthetized conditions. Magn Reson Imaging 2003;21:995-1001.
12. Sicard K, Shen Q, Brevard ME, et al. Regional cerebral blood flow and BOLD responses in conscious and anesthetized rats under basal and hypercapnic conditions: implications for functional MRI studies. J Cereb Blood Flow Metab 2003;23:472-481.
13. Steffey EP, Howland D Jr. Isoflurane potency in the dog and cat. Am J Vet Res 1977;38:1833-1836.
14. Beitz AJ, Fletcher TF The brain. In: Evans HE, ed. Millers anatomy of the dog. 3rd ed. Philadelphia: Saunders, 1993;894-952.
15. Guyton AC, Hall JE. Cerebral blood flow, cerebrospinal fluid and brain metabolism. In: Guyton AC, Hall JE, eds. Textbook of medical physiology. 11th ed. Philadelphia: Elsevier Saunders, 2006;761-768.
16. Drummond JC, Todd MM, Scheller MS, et al. A comparison of the direct cerebral vasodilating potencies of halothane and isoflurane in the New Zealand white rabbit. Anesthesiology 1986;65:462-467.
17. Hoffman WE, Edelman G, Kochs E, et al. Cerebral autoregulation in awake versus isoflurane-anesthetized rats. Anesth Analg 1991;73:753-757.
18. McPherson RW, Traystman RJ. Effects of isoflurane on cerebral autoregulation in dogs. Anesthesiology 1988;69:493-499.
19. Strebel S, Lam AM, Matta B, et al. Dynamic and static cerebral autoregulation during isoflurane, desflurane, and propofol anesthesia. Anesthesiology 1995;83:66-76.
20. Myburgh JA, Upton RN, Grant C, et al. The cerebrovascular effects of adrenaline, noradrenaline and dopamine infusions under propofol and isoflurane anaesthesia in sheep. Anaesth Intensive Care 2002;30:725-733.
21. Myburgh JA, Upton RN, Grant C, et al. The effect of infusions of adrenaline, noradrenaline and dopamine on cerebral autoregulation under isoflurane anaesthesia in an ovine model. Anaesth Intensive Care 2003;31:259-266.
22. von Essen C, Zervas NT, Brown DR, et al. Local cerebral blood flow in the dog during intravenous infusion of dopamine. Surg Neurol 1980;13:181-188.
23. Busija DW, Leffler CW, Pourcyrous M. Hyperthermia increases cerebral metabolic rate and blood flow in neonatal pigs. Am J Physiol 1988;255:H343-H346.
24. Michenfelder JD, Theye RA. Hypothermia: effect on canine brain and whole body metabolism. Anesthesiology 1968;29:1107-1112.
25. Krafft P, Frietsch T, Lenz C, et al. Mild and moderate hypothermia (alpha-stat) do not impair the coupling between local cerebral blood flow and metabolism in rats. Stroke 2000;31:1393-1400.
26. Haskins S, Pascoe PJ, Ilkiw JE, et al. Reference cardiopulmonary values in normal dogs. Comp Med 2005;55:156-161.
27. Myburgh JA, Upton RN, Ludbrook GL, et al. Cerebrovascular carbon dioxide reactivity in sheep: effect of propofol or isoflurane anaesthesia. Anaesth Intensive Care 2002;30:413-421.
28. McPherson RW, Briar JE, Traystman RJ. Cerebrovascular responsiveness to carbon dioxide in dogs with 1.4% and 2.8% isoflurane. Anesthesiology 1989;70:843-850.
29. Iida H, Ohata H, Iida M, et al. Isoflurane and sevoflurane induce vasodilation of cerebral vessels via ATP-sensitive K+ channel activation. Anesthesiology 1998;89:954-960.
30. Matta BF, Heath KJ, Tipping K, et al. Direct cerebral vasodilatory effects of sevoflurane and isoflurane. Anesthesiology 1999;91:677-680.
31. Matta BF, Mayberg TS, Lam AM. Direct cerebrovasodilatory effects of halothane, isoflurane, and desflurane during propofol-induced isoelectric electroencephalogram in humans. Anesthesiology 1995;83:980-985.
32. Willis CK, Quinn RP, McDonell WM, et al. Functional MRl as a tool to assess vision in dogs: the optimal anesthetic. Vet Ophthalmol 2001;4:243-253.
33. Floyd TF, Clark JM, Gelfand R, et al. Independent cerebral vasoconstrictive effects of hyperoxia and accompanying arterial hypocapnia at 1 ATA. J Appl Physiol 2003;95:2453-2461.
34. 2 induced increase in cerebral perfusion. NMR Biomed 1994;7:29-34.
35. Parrish TB, Gitelman DR, LaBar KS, et al. Impact of signal-to-noise on functional MRI. Magn Reson Med 2000;44:925-932.
36. Watson NA, Beards SC, Altaf N, et al. The effect of hyperoxia on cerebral blood flow: a study in healthy volunteers using magnetic resonance phase-contrast angiography. Eur J Anaesthesiol 2000;17:152-159.
37. Rostrup E, Larsson HB, Toft PB, et al. Signal changes in gradient echo images of human brain induced by hypo- and hyperoxia. NMR Biomed 1995;8:41-47.
38. Bulte DP, Chiarelli PA, Wise RG, et al. Cerebral perfusion response to hyperoxia. J Cereb Blood Flow Metab 2007;27:69-75.
39. Sicard KM, Duong TQ. Effects of hypoxia, hyperoxia, and hypercapnia on baseline and stimulus-evoked BOLD, CBF, and CMRO2 in spontaneously breathing animals. Neuroimage 2005;25:850-858.
40. Demchenko IT, Luchakov YI, Moskvin AN, et al. Cerebral blood flow and brain oxygenation in rats breathing oxygen under pressure. J Cereb Blood Flow Metab 2005;25:1288-1300.
41. Brown MM, Wade JP, Marshall J. Fundamental importance of arterial oxygen content in the regulation of cerebral blood flow in man. Brain 1985;108:81-93.
42. 2 carrier. J Cereb Blood Flow Metab 1994;14:871-876.