Utility of retention prediction model for investigation of peptide separation selectivity in reversed-phase liquid chromatography: impact of concentration of trifluoroacetic acid, column temperature, gradient slope and type of stationary phase

Analytical Chemistry

Volumn 82, Issue 1, 2010, Pages 265-275

  Gilar, Martin ^a   Xie, Hongwei ^a   Jaworski, Aleksander ^b  

^a WATERS CORPORATION   (United States)

^b NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID RESIDUES; CHROMATOGRAPHIC CONDITIONS; CHROMATOGRAPHIC SORBENTS; COLUMN TEMPERATURE; CONCENTRATION OF; ELEVATED TEMPERATURE; ION-PAIRING REAGENT; PEPTIDE SEPARATION; PREDICTION MODEL; RETENTION COEFFICIENTS; RETENTION PREDICTION; RETENTION TIME; REVERSED PHASE; REVERSED-PHASE LIQUID CHROMATOGRAPHY; STATIONARY PHASE; SYNTHETIC PEPTIDE; TRAINING SETS; TRIFLUOROACETIC ACIDS;

CHROMATOGRAPHIC ANALYSIS; COLUMN CHROMATOGRAPHY; LIQUID CHROMATOGRAPHY; LIQUIDS; MATHEMATICAL MODELS; ORGANIC ACIDS; PEPTIDES; PHOSPHATASES; POSITIVE IONS; SEPARATION; SORPTION;

AMINO ACIDS;

PEPTIDE; TRIFLUOROACETIC ACID;

ARTICLE; CHEMICAL MODEL; CHEMISTRY; INSTRUMENTATION; METHODOLOGY; REVERSED PHASE LIQUID CHROMATOGRAPHY; TEMPERATURE;

CHROMATOGRAPHY, REVERSE-PHASE; MODELS, CHEMICAL; PEPTIDES; TEMPERATURE; TRIFLUOROACETIC ACID;

EID: 75749089270     PISSN: 00032700     EISSN: None     Source Type: Journal    
DOI: 10.1021/ac901931c     Document Type: Article

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