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Volumn 46, Issue 6, 2010, Pages 901-903

Enantiomerically pure β-phenylalanine analogues from α-β-phenylalanine mixtures in a single reactive extraction step

Author keywords

[No Author keywords available]

Indexed keywords

BETA AMINO ACID; PALLADIUM CHLORIDE; PALLADIUM COMPLEX; PHENYLALANINE; PHENYLALANINE DERIVATIVE; UNCLASSIFIED DRUG;

EID: 75649151345     PISSN: 13597345     EISSN: None     Source Type: Journal    
DOI: 10.1039/b921661h     Document Type: Article
Times cited : (23)

References (19)
  • 17
    • 0039845930 scopus 로고    scopus 로고
    • a of 0.55 will lead to a concentration difference more than three times as high for the anions in a buffered solution
    • a of 0.55 will lead to a concentration difference more than three times as high for the anions in a buffered solution: D. Koch W. Hoffmuller K. Polborn W. Beck Z. Naturforsch., B: Chem. Sci. 2001 56 403
    • (2001) Z. Naturforsch., B: Chem. Sci. , vol.56 , pp. 403
    • Koch, D.1    Hoffmuller, W.2    Polborn, K.3    Beck, W.4
  • 19
    • 33646362757 scopus 로고    scopus 로고
    • >95% by SDS-PAGE with Coomassie staining As the conversion over 5 d was not complete, the mixture still contained (E)-cinnamic acid. To avoid interference with the isolation of β-Phe, (E)-cinnamic acid was removed by lowering the pH to pH = 2.0 by addition of HCl (aq) and subsequent extraction with dcm. The remaining α-β-Phe mixture was analyzed by RP-HPLC and showed that (E)-cinnamic acid was removed effectively. The α-β-Phe mixture was finally diluted 10 times with 100 mM aqueous phosphate buffer (pH = 7.0)
    • M. Steensma N. J. M. Kuipers A. B. De Haan G. Kwant Chirality 2006 18 314
    • (2006) Chirality , vol.18 , pp. 314
    • Steensma, M.1    Kuipers, N.J.M.2    De Haan, A.B.3    Kwant, G.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.