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1
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58149511900
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Pharmacokinetics, metabolism, and excretion of ritonavir-boosted GS-9137 (Elvitegravir)
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Presented at April 16-18, 2007; Budapest, Hungary. Abstract 30
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Ramanathan S, Wright M, West S, et al. Pharmacokinetics, metabolism, and excretion of ritonavir-boosted GS-9137 (Elvitegravir). Presented at: Eighth International Workshop on Clinical Pharmacology of HIV Therapy; April 16-18, 2007; Budapest, Hungary. Abstract 30.
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Eighth International Workshop on Clinical Pharmacology of HIV Therapy
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Ramanathan, S.1
Wright, M.2
West, S.3
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2
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58149519983
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Effect of increasing ritonavir doses on hepatic CYP3A activity and GS-9137 (elvitegravir) oral exposure
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Presented at April 16-18, 2007; Budapest, Hungary. Abstract 53
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Mathias AA, West S, Hui J, et al. Effect of increasing ritonavir doses on hepatic CYP3A activity and GS-9137 (elvitegravir) oral exposure. Presented at: Eighth International Workshop on Clinical Pharmacology of HIV Therapy; April 16-18, 2007; Budapest, Hungary. Abstract 53.
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Eighth International Workshop on Clinical Pharmacology of HIV Therapy
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Mathias, A.A.1
West, S.2
Hui, J.3
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3
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75649109139
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Clinical pharmacokinetics of once-daily elvitegravir boosted by ritonavir versus atazanavir
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Presented at April 7-9, 2008; New Orleans, LA. Abstract O18
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Ramanathan S, West S, Hui J, et al. Clinical pharmacokinetics of once-daily elvitegravir boosted by ritonavir versus atazanavir. Presented at: Ninth International Workshop on Clinical Pharmacology of HIV Therapy; April 7-9, 2008; New Orleans, LA. Abstract O18.
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Ninth International Workshop on Clinical Pharmacology of HIV Therapy
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Ramanathan, S.1
West, S.2
Hui, J.3
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4
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33748113778
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Antiviral activity, pharmacokinetics, and dose response of the HIV-1 integrase inhibitor GS-9137 (JTK-303) in treatment-naïve and treatment-experienced patients
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J Acquir Immune Defic Syndr
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Markowitz, M.3
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5
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55049114155
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The HIV integrase inhibitor elvitegravir (EVG/r) has potent and durable antiretroviral activity in treatment-experienced patients with active optimized background therapy (OBT) [H-714]
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Presented at September 17-20 Chicago, IL
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Zolopa A, Lampiris H, Blick G, et al. The HIV integrase inhibitor elvitegravir (EVG/r) has potent and durable antiretroviral activity in treatment-experienced patients with active optimized background therapy (OBT) [H-714]. Presented at: Forty Seventh Interscience Conference on Antimicrobial Agents and Chemotherapy; September 17-20, 2007; Chicago, IL.
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(2007)
Forty Seventh Interscience Conference on Antimicrobial Agents and Chemotherapy
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Zolopa, A.1
Lampiris, H.2
Blick, G.3
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6
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34248199833
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The HIV integrase inhibitor GS-9137 demonstrates potent antiretroviral activity in treatment-experienced patients [143LB]
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Presented at February 25-28 Los Angeles, CA
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Zolopa A, Mullen M, Berger D, et al. The HIV integrase inhibitor GS-9137 demonstrates potent antiretroviral activity in treatment-experienced patients [143LB]. Presented at: Fourteenth Conference on Retrovirus and Opportunistic Infections; February 25-28, 2007; Los Angeles, CA.
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(2007)
Fourteenth Conference on Retrovirus and Opportunistic Infections
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Zolopa, A.1
Mullen, M.2
Berger, D.3
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7
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0029417004
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Identification of RANTES MIP-1a and MIP-1b as the major HIV-suppressive factors produced by CD8+ T cells
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8
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16044370301
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HIV blocked by chemokine antagonist
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9
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54849146700
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Maraviroc for previously treated patients with R5 HIV-1 infection
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10
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Maraviroc: In vitro assessment of drug-drug interaction potential
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Hyland R, Dickins M, Collins C, et al. Maraviroc: in vitro assessment of drug-drug interaction potential. Br J Clin Pharmcol. 2008;66:498-507.
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Hyland, R.1
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11
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15344350690
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Species differences in the disposition of the CCR5 antagonist, UK-427, 857, a new potential treatment for HIV
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Walker DK, Abel S, Comby P, et al. Species differences in the disposition of the CCR5 antagonist, UK-427,857, a new potential treatment for HIV. Drug Metab Dispos. 2005;33:587-595.
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Walker, D.K.1
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12
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69849084582
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Maraviroc: Pharmacokinetics and drug interactions
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Abel S, Back DJ, Vourvahis M. Maraviroc: pharmacokinetics and drug interactions. Antivir Ther. 2009;14:607-618.
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Antivir Ther
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Abel, S.1
Back, D.J.2
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13
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58149489322
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Pharmacokinetics of elvitegravir and etravirine following coadministration of ritonavir-boosted elvitegravir and etravirine
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Ramanathan S, Kakuda TN, Mack, R, et al. Pharmacokinetics of elvitegravir and etravirine following coadministration of ritonavir-boosted elvitegravir and etravirine. Antivir Ther. 2008;13:1011-1017.
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Ramanathan, S.1
Kakuda, T.N.2
MacK, R.3
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14
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40549090550
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Effect of maraviroc on the pharmacokinetics of midazolam, lamivudine/zidovudine, and ethinyloe-stradiol/levonorgestrel in healthy volunteers
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Abel S, Russell D, Whitlock LA, et al. Effect of maraviroc on the pharmacokinetics of midazolam, lamivudine/zidovudine, and ethinyloe-stradiol/ levonorgestrel in healthy volunteers. Br J Clin Pharmacol. 2008; 65(Suppl 1):19-26.
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Br J Clin Pharmacol
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Abel, S.1
Russell, D.2
Whitlock, L.A.3
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15
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55249116493
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Effect of ritonavir-boosted tipranavir or darunavir on the steady-state pharmacokinetics of elvitegravir
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Mathias AA, Hinkle J, Shen G, et al. Effect of ritonavir-boosted tipranavir or darunavir on the steady-state pharmacokinetics of elvitegravir. J Acquir Immune Defic Syndr. 2008;49:156-162.
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Mathias, A.A.1
Hinkle, J.2
Shen, G.3
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16
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34347347164
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Pharmacokinetics of emtricitabine, tenofovir, and GS-9137 following co-administration of emtricitabine/tenofovir disoproxil fumarate and ritonavir-boosted GS-9137
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Ramanathan S, Shen G, Cheng A, et al. Pharmacokinetics of emtricitabine, tenofovir, and GS-9137 following co-administration of emtricitabine/tenofovir disoproxil fumarate and ritonavir-boosted GS-9137. J Acquir Immune Defic Syndr. 2007;45:274-279.
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J Acquir Immune Defic Syndr
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Ramanathan, S.1
Shen, G.2
Cheng, A.3
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17
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34748824953
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Pharmacokinetics of co-administered ritonavir-boosted elvitegravir and zidovudine, didanosine, stavudine, and abacavir
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Ramanathan S, Shen G, Hinkle J, et al. Pharmacokinetics of co-administered ritonavir-boosted elvitegravir and zidovudine, didanosine, stavudine, and abacavir. J Acquir Immune Defic Syndr. 2007;46:160-166.
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J Acquir Immune Defic Syndr
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Ramanathan, S.1
Shen, G.2
Hinkle, J.3
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18
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55249116493
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Effect of ritonavir-boosted tipranavir or darunavir on the steady-state pharmacokinetics of elvitegravir
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Mathias AA, Hinkle J, Shen G, et al. Effect of ritonavir-boosted tipranavir or darunavir on the steady-state pharmacokinetics of elvitegravir. J Acquir Immune Defic Syndr. 2008;49:156-162.
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Mathias, A.A.1
Hinkle, J.2
Shen, G.3
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19
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42149147700
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Lack of clinically relevant drug-drug interaction between ritonavir-boosted GS-9137 (elvitegravir) and fosamprenavir/r [WEBEP014]
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Presented at Sydney, Australia
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Ramanathan S, Mathias AA, Shen G, et al. Lack of clinically relevant drug-drug interaction between ritonavir-boosted GS-9137 (elvitegravir) and fosamprenavir/r [WEBEP014]. Presented at: Fourth International AIDS Society Conference on Pathogenesis, Treatment, and Prevention; 2007; Sydney, Australia.
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(2007)
Fourth International AIDS Society Conference on Pathogenesis Treatment and Prevention
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Ramanathan, S.1
Mathias, A.A.2
Shen, G.3
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20
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58149530512
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Pharmacokinetic evaluation of drug interactions with ritonavir-boosted HIV integrase inhibitor GS-9137 (elvitegravir) and acid reducing agents
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Presented at April 16-18 Budapest, Hungary. Abstract 69
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Ramanathan S, Shen G, Hinkle J, et al. Pharmacokinetic evaluation of drug interactions with ritonavir-boosted HIV integrase inhibitor GS-9137 (elvitegravir) and acid reducing agents. Presented at: Eighth International Workshop on Clinical Pharmacology of HIV Therapy; April 16-18, 2007; Budapest, Hungary. Abstract 69.
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(2007)
Eighth International Workshop on Clinical Pharmacology of HIV Therapy
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Ramanathan, S.1
Shen, G.2
Hinkle, J.3
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21
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40549086936
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Effects of CYP3A4 inducers with and without CYP3A4 inhibitors on the pharmacokinetics of maraviroc in healthy volunteers
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Abel S, Jenkins TM, Whitlock LA, et al. Effects of CYP3A4 inducers with and without CYP3A4 inhibitors on the pharmacokinetics of maraviroc in healthy volunteers. Br J Clin Pharmacol. 2008;65(Suppl 1): 38-46.
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Abel, S.1
Jenkins, T.M.2
Whitlock, L.A.3
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22
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33845688834
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An investigation of the effects of atazanavir and ritonavir boosted atazanavir on the pharmacokinetics of the novel CCR5 inhibitor UK-427, 857
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Presented at November 14-18 Glasgow, United Kingdom
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Muirhead G, Abel S, Russell D, et al. An investigation of the effects of atazanavir and ritonavir boosted atazanavir on the pharmacokinetics of the novel CCR5 inhibitor UK-427,857. Presented at: 7th International congress on drug therapy in HIV infection [P283]; November 14-18, 2004; Glasgow, United Kingdom.
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(2004)
7th International Congress on Drug Therapy in HIV Infection [P283]
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Muirhead, G.1
Abel, S.2
Russell, D.3
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23
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34548262047
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An open randomized 2-way crossover study to investigate the effect of darunavir/ritonavir on the pharmacokinetics of maraviroc in healthy subjects
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Presented at April 16-18 Budapest, Hungary. Abstract 55
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Abel S, Ridgway C, Hamlin J, et al. An open, randomized, 2-way crossover study to investigate the effect of darunavir/ritonavir on the pharmacokinetics of maraviroc in healthy subjects. Presented at: Eighth International Workshop on Pharmacology of HIV Therapy; April 16-18, 2007; Budapest, Hungary. Abstract 55.
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(2007)
Eighth International Workshop on Pharmacology of HIV Therapy
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Abel, S.1
Ridgway, C.2
Hamlin, J.3
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24
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57749197592
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Dose-response of ritonavir on hepatic CYP3A activity and elvitegravir oral exposure
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Mathias AA, West S, Hui J, et al. Dose-Response of Ritonavir on Hepatic CYP3A Activity and Elvitegravir Oral Exposure. Clin Pharmacol Ther. 2008;85:64-70.
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Clin Pharmacol Ther
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Mathias, A.A.1
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25
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35649022566
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A study to investigate the combined coadministration of P450 CYP3A4 inhibitors and inducers on the pharmacokinetics of the novel CCR5 inhibitor UK-427, 857 [P284]
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Presented at November 14-18 Glasgow, United Kingdom
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Muirhead G, Ridgway C, Leahy D. A study to investigate the combined coadministration of P450 CYP3A4 inhibitors and inducers on the pharmacokinetics of the novel CCR5 inhibitor UK-427,857 [P284]. Presented at: Seventh International congress on drug therapy in HIV infection; November 14-18, 2004; Glasgow, United Kingdom.
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(2004)
Seventh International Congress on Drug Therapy in HIV Infection
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Muirhead, G.1
Ridgway, C.2
Leahy, D.3
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