Replacement of adenovirus type 5 fiber shaft heparan sulfate proteoglycan-binding domain with RGD for improved tumor infectivity and targeting.

Human gene therapy

Volumn 20, Issue 10, 2009, Pages 1214-1221

  Bayo Puxan, Neus ^a   Gimenez Alejandre, Marta ^a   Lavilla Alonso, Sergio ^a   Gros, Alena ^a   Cascallo, Manel ^a   Hemminki, Akseli ^a   Alemany, Ramon ^a  

^a BELLVITGE BIOMEDICAL RESEARCH INSTITUTE IDIBELL   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ARGINYL-GLYCYL-ASPARTIC ACID; ARGINYLGLYCYLASPARTIC ACID; LUCIFERASE; OLIGOPEPTIDE; PROTEOHEPARAN SULFATE;

ADENOVIRUS; ANIMAL; ARTICLE; CHEMISTRY; ENZYMOLOGY; GENE VECTOR; GENETIC RECOMBINATION; GENETIC TRANSDUCTION; GENETICS; HUMAN; LIVER; METABOLISM; MOUSE; NEOPLASM; PROTEIN TERTIARY STRUCTURE; TISSUE DISTRIBUTION; TUMOR CELL LINE; VIROLOGY;

ADENOVIRIDAE; ANIMALS; CELL LINE, TUMOR; GENETIC VECTORS; HEPARAN SULFATE PROTEOGLYCANS; HUMANS; LIVER; LUCIFERASES; MICE; NEOPLASMS; OLIGOPEPTIDES; PROTEIN STRUCTURE, TERTIARY; RECOMBINATION, GENETIC; TISSUE DISTRIBUTION; TRANSDUCTION, GENETIC;

EID: 75649140935     PISSN: None     EISSN: 15577422     Source Type: Journal    
DOI: 10.1089/hum.2009.038     Document Type: Article

References (0)