Immunomodulatory activity of methanolic extract of Morus alba Linn. (mulberry) leaves

Pakistan Journal of Pharmaceutical Sciences

Volumn 23, Issue 1, 2010, Pages 63-68

  Bharani, Shendige Eswara Rao ^a   Asad, Mohammed ^a   Dhamanigi, Sunil Samson ^a   Chandrakala, Gowda Kallenahalli ^b  

^a KRUPANIDHI COLLEGE OF PHARMACY   (India)

^b Institute of Animal Health and Veterinary Biologicals   (India)

Author keywords

Cell mediated immunity; Humoral immunity; Morus alba Linn.; Phagocytic index; Serum immunoglobulin

Indexed keywords

CARBON; CYCLOPHOSPHAMIDE; ENDOXAN INJECTION; IMMUNOGLOBULIN; MULBERRY EXTRACT; OCIMUM SANCTUM EXTRACT; PLANT EXTRACT; UNCLASSIFIED DRUG;

AGGLUTINATION TEST; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY TITER; ARTICLE; CELL ADHESION; CONTROLLED STUDY; FEMALE; IMMUNOGLOBULIN BLOOD LEVEL; IMMUNOMODULATION; LETHALITY; MORUS ALBA; MOUSE; MULBERRY; NEUTROPENIA; NEUTROPHIL; NONHUMAN; PASTEURELLA MULTOCIDA INFECTION; PHAGOCYTOSIS; PLANT LEAF; RAT;

ANIMALS; DRUG EVALUATION, PRECLINICAL; IMMUNITY, CELLULAR; IMMUNITY, HUMORAL; IMMUNOLOGIC FACTORS; METHANOL; MICE; MODELS, ANIMAL; MORUS; OCIMUM; PLANT EXTRACTS; RATS; RATS, WISTAR;

EID: 75649131892     PISSN: 1011601X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (30)

1. Bown D (1995). Encyclopedia of herbs and their uses. Dorling Kindersley, London, UK, pp 313-314.
2. Chen F, Nakashima N, Kimura I and Kimura M (1995). Hypoglycemic activity and mechanisms of extracts from mulberry leaves (Folium mori) and cortex mori radicis in streptozotocin-induced diabetic mice. Yakugaku Zasshi, 115: 476-482.
3. Diwanay S, Chitre D and Patwardhan B (2004). Immunoprotection by botanical drugs in cancer chemotherapy. J. Ethnopharmacol., 90: 49-55.
4. Duke JA and Wain KK (1981). Medicinal plants of the world. Retrieved from www.hort.purdue.edu/newcrop/duke-energy/Morus-alba.html on 16/03/2008 at 3.00 PM. IST.
5. Duke JA and Ayensu ES (1985). Medicinal plants of china, Reference Publications, Inc. Retrieved from www.pfaf.org/database/Plants.php? Platycodon+grandif lorus on 16/03/2008 at 4.00 PM. IST.
6. Fang SH, Hou YC and Chao PD (2005). Pharmacokinetic and pharmacodynamic interactions of morin and cyclosporine. Toxicol. Appl. Pharmacol., 205(1): 65-70.
7. Finco Kent DL, Galvin JE, Suiter BT and Huether MJ (2001). Pasteurella multocida toxin type D serological assay as an alternative to the toxin neutralisation lethality test in mice. Biologicals, 29(1): 7-10.
8. Fulzele SV, Satturwar PM, Joshi SB and Dorle AK (2003). Study of the immunomodulatory activity of Haridradi Ghrita in rats. Indian J. Pharmacol., 35: 51-54.
9. Gokhale AB, Damre AS and Saraf MN (2003). Investigations into the immunomodulatory activity of Argyreia speciosa. J. Ethnopharmacol., 84: 109-114.
10. Hansawasdi C and Kawabata J. Evaluation of carbohydrate digestive enzymes inhibitory activity in various Thai herbs. Retrieved from www.indianmedi cine.ub.rug.nl/h.shtml on 27/09/06 at 2.00 PM. IST.
11. Him-Che Y (1985). Handbook of Chinese Herbs and Formulas. Institute of Chinese Medicine, Los Angeles, UK, pp 176, 218, 238.
12. Jayal MM, Kehar ND (1962). A study on the nutritive value of mulberry (Morus alba) tree leaves. Indian J. Dairy Sci; 15: 21-27.
13. Jayathirtha MG and Mishra SH (2004). Preliminary immunomodulatory activities of methanol extracts of Eclipta alba and Centella asiatica. Phytomedicine, 11: 361-365.
14. Kim HM, Han SB, Lee Kh, Lee CW, Kim CY, Lee EJ and Huch H (2000). Immunomodulating activity of a polysaccharide isolated form Mori cortex radicis. Arch. Pharm. Res., 23: 240-242.
15. Kimura Y and Hiromichi (1986). Effects of phenolic constituents from the mulberry tree on arachidonate metabolism in rat platelets. J. Nat. Prod., 49: 639-644.
16. Lemus I, Garcia R, Delvillar E and Knop G (1999). Hypoglycemic activity of four plants used in Chilean popular medicine. Phytother. Res., 13: 91-94.
17. Llamapaedia, testing for passive transfer. Retrieved from http://www.llamapaedia.com/crias/iggtest.html. 23.12.2005 at 02.00 PM. IST.
18. Mullen PA (1975). Zinc sulphate turbidity test as an aid to diagnosis. Veter. Annu., 15: 451-455.
19. Nam SY, YI HK, Lee JC, Kim Jc, Song CH, Park JW and Lee Dy Cortex (2002). Mori extract induces cancer cell apoptosis through inhibition of microtubule assembly. Arch. Pharm. Res., 25(2): 191-196.
20. Oku T, Yamada M, Nakamura M, Sadamori N and Nakamura S (2006). Inhibitory effects of extractives from leaves of Morus alba on human and rat small intestinal disaccharides activity. Br. J. Nutr., 95(5): 933-938.
21. Ouyang ZC. Research progress on chemical constituents and pharmacological activities of Mulberry leaves. Retrieved from www.scholar.ilib.cn/abstract. aspx?A=jslgdxxb200306010 on 27/09/06 at 12.35. PM. IST.
22. Ramanatha KR, Lakshminaryana R and Gopal T (1995). Potency test of Duck Pasteurella vaccine in mice. Mysore J. Agri. Sci., 29: 155-157.
23. Rao SA, Kumar AMN and Sampath SR (1971). Studies on mulberry (Morus indica) leaf stalk palatability, chemical composition and nutritive value. Indian Veter J; 48: 853-857.
24. Sergio W (1989). Mulberry roots and seeds may be effective in the treatment of AIDS. Med. Hypothesis, 29(1): 75-76.
25. Sharma M, Kishore K, Gupta SK, Joshi S and Arya DS (2001). Cardioprotective potential of ocimum sanctum in rats. Mole. Cellu. Biochem., 225 (1-2): 75-83.
26. Shinde UA, Phadke AS, Nair AM, Mungantiwar AA, Dikshit VJ and Saraf MN (1999) Preliminary studies on the immunomodulatory activity of Cedrus deodara wood oil. Fitoterapia, 70: 333-339.
27. Srikumar R, Narayanaperumal JP and Rathisamy SD (2005). Immunomodulatory activity of Triphala over neutrophil functions. Biol. Pharm. Bull., 28(8): 139-1403.
28. Taniguchi S, Asano N, Tomino F and Miwa I (1998). Potentiation of glucose- induced insulin secretion by fagomine, a pseudo-sugar isolated from mulberry leaves. Horm. Metab. Res., 30: 679-683.
29. Thatte UM, Chhabria SN, Karandikar SM and Dahanukar SA (1987). Protective effects of Indian medicinal plants against cyclophosphamide neutropenia. J. Postgrad. Med., 33(4): 185-88.
30. VitaNet ® Staff (support@vitanet.net). Folic Acid: Strengthening the Immune System in the Elderly. Retrieved from http://vitanetonline.com/forums/1/ Thread/824 on 12/03/2008 at 7.50 PM. IST.