Preparation and evaluation of microemulsion systems containing salicylic acid

AAPS PharmSciTech

Volumn 10, Issue 4, 2009, Pages 1081-1084

  Badawi, Alia A ^a   Nour, Samia A ^a   Sakran, Wedad S ^b   El Mancy, Shereen Mohamed Sameh ^b  

^a CAIRO UNIVERSITY   (Egypt)

^b 6th of October   (Egypt)

Author keywords

Microemulsion; Salicylic acid; Stability

Indexed keywords

DRUG VEHICLE; KERATOLYTIC AGENT; MYRISTIC ACID ISOPROPYL ESTER; POLYSORBATE 80; PROPYLENE GLYCOL; SALICYLIC ACID;

ARTICLE; CENTRIFUGATION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DRUG SCREENING; DRUG SOLUBILITY; DRUG STABILITY; DRUG SYNTHESIS; FLOW KINETICS; FREEZING; MICROEMULSION; PH; POLARIZATION MICROSCOPY; RELATIVE DENSITY; SHEAR RATE; THAWING; THERMODYNAMICS; TOPICAL DRUG ADMINISTRATION; VISCOSITY;

DRUG STABILITY; EMULSIONS; HYDROGEN-ION CONCENTRATION; SALICYLIC ACID; VISCOSITY;

EID: 75649128767     PISSN: None     EISSN: 15309932     Source Type: Journal    
DOI: 10.1208/s12249-009-9301-7     Document Type: Article

References (29)

1. K Collier S Matalonis AJ Owen 1999 Evaluation of permeability enhancement by microemulsion in a caco-2 cell system Proc Int Symp Control Release Bioact Mater 26 5444
2. RG Alany T Rades S Agatonovic-Kustrin NM Dvies IG Tucker 2000 Effects of alcohols and diols on the phase behaviour of quaternary systems Int J Pharm 196 141 145 10.1016/S0378-5173(99)00408-1 1:CAS:528:DC%2BD3cXhtl2qtrk%3D 10699705 (Pubitemid 30105730)
3. M Trotta F Pattarino G Grosa 1998 Formation of lecithin-based microemulsions containing n-alkanol phosphocholines Int J Pharm 174 253 259 10.1016/S0378-5173(98)00273-7 1:CAS:528:DyaK1cXmsFGnu7w%3D (Pubitemid 28487009)
4. G Marti-Mestres F Nielloud 2002 Emulsions in health care applications-an overview J Dispers Sci Technol 23 419 439 1:CAS:528:DC%2BD38XkslWktbo%3D
5. DW Osborne AJ Ward KJ O'Neill 1991 Microemulsions as topical drug delivery vehicles: in-vitro transdermal studies of a model hydrophilic drug J Pharm Pharmacol Comm 43 451 454 1:CAS:528:DyaK3MXlsVais70%3D
6. J Jachowicz MD Berthiaume 1993 Microemulsions vs. macroemulsions in hair care products Cosmet Toiletries 108 65 72 1:CAS:528:DyaK3sXksl2ku70%3D
7. DS Orth J Widjaja L Ly N Cao WB Shapiro 1998 Stability and skin persistence of topical products: evaluating the effect of a hydroalcoholic hydroquinone vehicle Cosmet Toiletries 113 10 51 63
8. Reynolds JEF, editor. Martindale, the extra pharmacopoeia, 30th edition. London: The Pharmaceutical Press; 1993.
9. SJ Bashir F Dreher AL Chew H Zhai C Levin R Stern, et al. 2005 Cutaneous bioassay of salicylic acid as a keratolytic Int J Pharm 292 187 194 10.1016/j.ijpharm.2004.11.032 1:CAS:528:DC%2BD2MXhs1GgsLc%3D 15725565 (Pubitemid 40255800)
10. KS Leslie G Dootson JC Sterling 2005 Topical salicylic acid gel as a treatment for molluscum contagiosum in Children J Derm Treat 16 336 340 10.1080/09546630500430521 1:CAS:528:DC%2BD28Xmtlyqug%3D%3D (Pubitemid 43170206)
11. WB Park SH Kim JH Cho JH Bang HB Kim NJ Kim, et al. 2007 Effect of salicylic acid on invasion of human vascular endothelial cells by Staphylococcus aureus FEMS Immunol Med Microbiol 49 56 61 10.1111/j.1574-695X.2006.00170 10.1111/j.1574-695X.2006.00170.x 1:CAS:528:DC%2BD2sXhvVOit7k%3D 17094786
12. LI Kupferwasser MR Yeaman CC Nast D Kupferwasser YQ Xiong M Palma, et al. 2003 Salicylic acid attenuates virulence in endovascular infections by targeting global regulatory pathways in Staphylococcus aureus J Clin Invest 112 2 222 233 10.1172/JC1200316876 1:CAS:528:DC%2BD3sXlslWltL4%3D 12865410
13. British Medical Association and the Royal Pharmaceutical Society of Great Britain. British National Formulary, No. 26; 1993. p. 408-10.
14. ZD Draelos 2005 An evaluation of topical 3% salicylic acid and 1% hydrocortisone in the maintenance of scalp pruritus J Cosmet Dermatol 4 193 197 10.1111/j.1473-2165.2005.00311.x 17129266
15. HS Lee IH Kim 2003 Salicylic acid peels for the treatment of acne vulgaris in Asian patients Dermatol Surg 29 1196 1199 10.1111/j.1524-4725.2003. 29384.x 14725662 (Pubitemid 38009918)
16. E Pearl MD Grimes 1999 The safety and efficacy of salicylic acid chemical peels in darker racial-ethnic groups Dermatol Surg 25 1 18 22 10.1046/j.1524-4725.1999.08145.x (Pubitemid 29242727)
17. HH Ahn IH Kim 2006 Whitening effect of salicylic acid peels in Asian patients Dermatol Surg 32 372 375 10.1111/j.1524-4725.2006.32075 1:CAS:528:DC%2BD2sXit1Wrug%3D%3D 16640681
18. HB Gladstone BA Nguyen R Williams T Ottomeyer M Wortzman M Jeffers, et al. 2000 Efficacy of hydroquinone cream (USP 4%) used alone or in combination with salicylic acid peels in improving photodamage on the neck and upper chest Dermatol Surg 26 4 333 377 10.1046/j.1524-4725.2000.99233.x 1:STN:280: DC%2BD3czpt1Cjtg%3D%3D 10759820 (Pubitemid 30207951)
19. T Dainichi S Ueda M Isoda T Koga N Kinukawa Y Nose, et al. 2003 Chemical peeling with salicylic acid in polyethylene glycol vehicle suppresses skin tumour development in hairless mice Br J Dermatol 148 906 912 10.1046/j.1365-2133.2003.05282.x 1:CAS:528:DC%2BD3sXlslarsL4%3D 12786820 (Pubitemid 36750782)
20. A Klimowicz S Farfał S Bielecka-Grzela 2007 Evaluation of skin penetration of topically applied drugs in humans by cutaneous microdialysis: acyclovir vs. salicylic acid J Clin Pharm Ther 32 143 148 10.1111/j.1365-2710. 2007.00803.x 1:CAS:528:DC%2BD2sXltFKlur4%3D 17381664 (Pubitemid 46449702)
21. Badawi AA, Nour SA, Sakran WS, El-Mancy SS. Formulation and evaluation of new emulsion systems as dosage forms. MD thesis submitted to faculty of pharmacy, Egypt: Cairo University; 2006.
22. C Malcolmson M Lawrence 1995 Three-component non-ionic oil-in-water microemulsions using polyoxyethylene ether surfactants Colloids Surf., B Biointerfaces 4 97 109 10.1016/0927-7765(94)01160-7 1:CAS:528:DyaK2MXjvFyjsb4%3D
23. PP Constantinides JP Scalart C Lancaster J Marcello G Marks H Ellens, et al. 1994 Formulation and intestinal absorption enhancement evaluation of water-in-oil microemulsions incorporating medium-chain glycerides Pharm Res 11 10 1385 1390 10.1023/A:1018927402875 1:CAS:528:DyaK2MXivFaltLk%3D 7855039 (Pubitemid 24339642)
24. PP Constantinides G Welzel H Ellens PL Smith S Sturgis SH Yiv, et al. 1996 Water-in-oil microemulsions containing medium-chain fatty acids/salts: formulation and intestinal absorption enhancement evaluation Pharm Res 13 2 210 215 10.1023/A:1016030812272 1:CAS:528:DyaK28Xht1Okurw%3D 8932438 (Pubitemid 26072140)
25. SA Nour SH Shalaby NN Afify S Abd El-Aal MK Mekhael 2002 Formulation and evaluation of econazole nitrate emulgels J Drug Res Egypt 24 1-2 63 71 1:CAS:528:DC%2BD3sXnt1yltb0%3D
26. MJ Lucero J Vigo MJ Leon 1994 A study of shear and compression deformations on hydrophilic gels of tretinoin Int J Pharm 106 125 133 10.1016/0378-5173(94)90310-7 1:CAS:528:DyaK2cXktFOrtLw%3D (Pubitemid 24136530)
27. B Brime MA Moreno G Frutos MA Ballesteros P Frutos 2002 Amphotericin B in oil-water lecithin-based microemulsions: formulation and toxicity evaluation J Pharm Sci 91 4 1178 1185 10.1002/jps.10065 1:CAS:528:DC%2BD38XjtFKgsr8%3D 11948556 (Pubitemid 34640942)
28. S Kantaria GD Rees MJ Lawrence 1999 Gelatin-stabilized microemulsion-based organogels: rheology and application in iontophoretic transdermal drug delivery J Control Release 60 355 365 10.1016/S0168-3659(99) 00092-9 1:CAS:528:DyaK1MXks1Gjs7o%3D 10425340 (Pubitemid 29335960)
29. L Baudonnet J-L Grossiord F Rodriguez 2004 Physicochemical characterization and in vitro release of salicylic acid from o/w emulsions prepared with Montanov 68®: effect of formulation parameters Drug Dev Ind Pharm 30 11 975 984 10.1081/DDC-200037251 1:CAS:528:DC%2BD2cXosVKmt78%3D 15554222 (Pubitemid 39453049)