The use of the dicentric assay for biological dosimetry for radiation accidents in bulgaria

Health Physics

Volumn 98, Issue 2, 2010, Pages 252-257

  Hadjidekova, Valeria ^a   Hristova, Rositsa ^a   Ainsbury, Elizabeth A ^b   Atanasova, Petya ^a   Popova, Ljubomira ^a   Staynova, Albena ^a  

^a National Center of Radiobiology and Radiation Protection Bulgaria   (Bulgaria)

^b PUBLIC HEALTH ENGLAND   (United Kingdom)

Author keywords

137Cs; 192Ir; 60Co; Dosimetry

Indexed keywords

ARTICLE; BIOASSAY; BODY BURDEN; BULGARIA; CHROMOSOME ABERRATION; ENVIRONMENTAL EXPOSURE; HUMAN; METHODOLOGY; MICRONUCLEUS TEST; NUCLEAR ACCIDENT; RADIATION DOSE; RADIATION EXPOSURE; RADIOMETRY; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY;

BIOLOGICAL ASSAY; BODY BURDEN; BULGARIA; CHROMOSOME ABERRATIONS; ENVIRONMENTAL EXPOSURE; HUMANS; MICRONUCLEUS TESTS; RADIATION DOSAGE; RADIOACTIVE HAZARD RELEASE; RADIOMETRY; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY;

EID: 75649125626     PISSN: 00179078     EISSN: None     Source Type: Journal    
DOI: 10.1097/HP.0b013e3181ab3ccf     Document Type: Article

References (17)

1. Ainsbury EA, Lloyd DC. Dose estimation software for radiation biodosimetry. Health Phys 98(2):290 -295; 2010.
2. Barquinero JF, Barrios L, Caballin MR, Miró R, Ribas M, Subias A, Egozcue J. Establishment and validation of a dose-effect curve for gamma-rays by cytogenetic analysis. Mutat Res 326:65- 69; 1995.
3. 60Co γ-irradiation. Radiat Environ Biophys 22:225-229; 1983.
4. Bauchinger M. Cytogenetic effects in human lymphocytes as a dosimetry system. In Biological Dosimetry (Eisert WG, Mendelsohn ML, eds.). Berlin: Springer-Verlag; 1994: 15-24.
5. Diyankov VS, Kovalev VP, Kormilitsyi AI, Lavrent'ev BP. High-power pulse generators for bremsstrahlung and electron beams using inductive energy accumulators. Russian Phys J 38:84 -92; 1995.
6. International Atomic Energy Agency. Biological dosimetry: chromosomal aberration analysis for dose assessment. Vienna: IAEA; Technical Reports Series No. 260; 1986.
7. International Atomic Energy Agency. Cytogenetic analysis for radiation dose assessment: a manual. Vienna: IAEA; Technical Reports Series No. 405; 2001.
8. Lea DE, Catcheside DG. The mechanism of the induction by radiation of chromosome aberrations in Tradescantia. J Genet 44:216 -245; 1942.
9. Lindholm C, Luomahaara S, Koivistoinen A, Ilus T, Edwards AA, Salomaa S. Comparison of dose-response curves for chromosome aberrations established by chromosome pairing and conventional analysis. Int J Radiat Biol 75:27-34; 1998.
10. Lloyd DC, Purrot RJ, Dolphin GW, Bolton D, Eduards AA. The relationship between chromosome aberration and low LET radiation dose to human lymphocytes. Int J Radiat Biol 28:75-90; 1975.
11. Lloyd DC, Purrot RJ. Chromosome aberration analysis in radiological protection dosimetry. Radiat Protect Dosim 1:19 -28; 1981.
12. Lloyd DC, Edwards AA, Prosser JS. Chromosome aberrations induced in human lymphocytes by in vitro acute x and gamma radiation. Radiat Protect Dosim 15:83- 88; 1986.
13. Lucas JN, Awa A, Straume T, Poggensee M, Kodama Y, Nakano M, Ohtaki K, Weier H-U, Pinkel D, Gray J, Littlefield G. Rapid translocation frequency analysis in humans decades after exposure to ionizing radiation. Radiat Biol 62:53- 63; 1992.
14. Miller SM, Ferrarotto CL, Vlahovich S, Wilkins RC, Boreham DR, Dolling J-A. Biological dosimetry following radiological/ nuclear accidents. Radiat Biol 83:471- 478; 2007.
15. Prasanna PG, Loats H, Gerstenberg HM, Torres BN, Shehata CW, Duffy KL, Floura RS, Khusen AW, Jackson WE, Blakely WF. AFRRI's gamma-ray, x-ray, and fissionneutron calibration curves for the lymphocyte dicentric assay: application of a metaphase finder system. Armed Forces Radiobiology Research Institute Technical Report. Bethesda, MD: Armed Forces Radiobiology Research Institute; 2002.
16. Szluinska M, Edwards AA, Lloyd DC. Statistical methods for biological dosimetry. In: Chromosomal aberrations, methods, results and importance in human health (Obe G, Vijayalaxmi, eds.). Berlin, Heidelberg: Springer; 2007:351-370.
17. Wolf S. Biological dosimetry with cytogenetic endpoints. In: Gledhill BL, Mauro F, eds. New horizons in biological dosimetry. New York: Willey-Liss Inc.; 1999: 351-362.