Manganese in the air: Are children at greater risk than adults?

Journal of Toxicology and Environmental Health - Part A: Current Issues

Volumn 73, Issue 2-3, 2010, Pages 156-158

  Winder, Bruce S ^a  

^a CALIFORNIA ENVIRONMENTAL PROTECTION AGENCY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MANGANESE;

ADULT; AIR POLLUTANT; AMBIENT AIR; CHILD; CONFERENCE PAPER; DIETARY INTAKE; DISEASE PREDISPOSITION; ENVIRONMENTAL EXPOSURE; GROUPS BY AGE; HUMAN; INHALATION; PRIORITY JOURNAL; RISK ASSESSMENT; TOXICOKINETICS;

ADOLESCENT; ADULT; AGE DISTRIBUTION; AIR POLLUTANTS; CHILD; CHILD, PRESCHOOL; ENVIRONMENTAL EXPOSURE; HUMANS; INFANT; INFANT, NEWBORN; INHALATION EXPOSURE; MANGANESE; MIDDLE AGED; PHARMACOKINETICS; RISK ASSESSMENT; YOUNG ADULT;

EID: 75649116748     PISSN: 15287394     EISSN: 10872620     Source Type: Journal    
DOI: 10.1080/15287390903340401     Document Type: Conference Paper

References (17)

1. Andersen, M. E., Gearhart, J. M., and Clewell, H. J. 3rd. 1999. Pharmacokinetic data needs to support risk assessments for inhaled and ingested manganese. Neurotoxicology 20: 161-171.
2. Arcus-Arth, A., and Blaisdell, R. J. 2007. Statistical distributions of daily breathing rates for narrow age groups of infants and children. Risk Anal. 27:97-110.
3. Beard, J. L. 2001. Iron biology in immune function, muscle metabolism and neuronal functioning. J. Nutr. 131(suppl.2):568S-579S; discussion 580S.
4. Brain, J. D., Heilig, E., Donaghey, T. C., Knutson, M. D., Wessling-Resnick, M., and Molina, R. M. 2006. Effects of iron status on transpulmonary transport and tissue distribution of Mn and Fe. Am. J. Respir. Cell Mol. Biol. 34:330-337.
5. Dorman, D. C., Struve, M. F., James, R. A., McManus, B. E., Marshall, M. W., and Wong, B. A. 2001. Influence of dietary manganese on the pharmacokinetics of inhaled manganese sulfate in male CD rats. Toxicol. Sci. 60:242-251.
6. Dorman, D. C., Struve, M. F., and Wong, B. A. 2002. Brain manganese concentrations in rats following manganese tetroxide inhalation are unaffected by dietary manganese intake. Neurotoxicology 23:185-195.
7. Dorman, D. C., Struve, M. F., Wong, B. A., Dye, J. A., and Robertson, I. D. 2006a. Correlation of brain magnetic resonance imaging changes with pallidal manganese concentrations in rhesus monkeys following subchronic manganese inhalation. Toxicol. Sci. 92:219-227.
8. Dorner, K., Dziadzka, S., Hohn, A., Sievers, E., Oldigs, H. D., Schulz-Lell, G., and Schaub, J. 1989. Longitudinal manganese and copper balances in young infants and preterm infants fed on breast-milk and adapted cow's milk formulas. Br. J. Nutr. 61:559-572.
9. Drown, D. B., Oberg, S. G., and Sharma, R. P. 1986. Pulmonary clearance of soluble and insoluble forms of manganese. J. Toxicol. Environ. Health 17:201-212.
10. Erikson, K. M., Shihabi, Z. K., Aschner, J. L., and Aschner, M. 2002. Manganese accumulates in iron-deficient rat brain regions in a heterogeneous fashion and is associated with neurochemical alterations. Biol. Trace Elem. Res. 87:143-156.
11. Food and Nutrition Board. 2004. Dietary reference intake tables: Elements table. Food and Nutrition Board, Institutes of Medicine.
12. Garcia, S. J., Gellein, K., Syversen, T., and Aschner, M. 2006. A manganese-enhanced diet alters brain metals and transporters in the developing rat. Toxicol. Sci. 92:516-525.
13. Mena, I. 1974. The role of manganese in human disease. Ann. Clin. Lab. Sci. 4:487-491.
14. Office of Environmental Health Hazard Assessment. 2000. The Air Toxics Hot Spots Program risk assessment guidelines, Part IV: Technical Support document for exposure assessment and stochastic analysis. Sacramento, CA: Air Toxicology and Epidemiology Section, Office of Environmental Health Hazard Assessment, California Environmental Protection Agency.
15. Roels, H. A., Ghyselen, P., Buchet, J. P., Ceulemans, E., and Lauwerys, R. R. 1992. Assessment of the permissible exposure level to manganese in workers exposed to manganese dioxide dust. Br. J. Ind. Med. 49:25-34.
16. Roels, H., Meiers, G., Delos, M., Ortega, I., Lauwerys, R., Buchet, J. P., and Lison, D. 1997. Influence of the route of administration and the chemical form (MnCl2, MnO2) on the absorption and cerebral distribution of manganese in rats. Arch. Toxicol. 71: 223-230.
17. Thompson, K., Molina, R. M., Donaghey, T., Schwob, J. E., Brain, J. D., and Wessling-Resnick, M. 2007. Olfactory uptake of manganese requires DMT1 and is enhanced by anemia. FASEB J. 21:223-230.