Reduced pressure ice fog technique for controlled ice nucleation during freeze-drying

AAPS PharmSciTech

Volumn 10, Issue 4, 2009, Pages 1406-1411

  Patel, Sajal M ^a   Bhugra, Chandan ^b   Pikal, Michael J ^a  

^a UNIVERSITY OF CONNECTICUT   (United States)

^b BOEHRINGER INGELHEIM PHARMACEUTICALS INC   (United States)

Author keywords

Controlled ice nucleation; Freeze drying; Ice fog; Reduced pressure; Scale up

Indexed keywords

SUCROSE;

ARTICLE; CONCENTRATION RESPONSE; CONTROLLED ICE NUCLEATION; CONTROLLED STUDY; FREEZE DRYING; LOW TEMPERATURE PROCEDURES; MANOMETRY; PRESSURE CHAMBER; PRESSURE GRADIENT; TEMPERATURE MEASUREMENT;

FREEZE DRYING; ICE; PRESSURE; SURFACE PROPERTIES; TECHNOLOGY, PHARMACEUTICAL; TEMPERATURE;

EID: 75549083533     PISSN: None     EISSN: 15309932     Source Type: Journal    
DOI: 10.1208/s12249-009-9338-7     Document Type: Article

References (10)

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