Expression pattern of aquaporin 4 and 5 in the middle ear of guinea pigs with secretory otitis media

Acta Oto-Laryngologica

Volumn 130, Issue 1, 2010, Pages 68-74

  Zhang, Qian ^a   Liu, Changjian ^a   Wang, Jianqun ^a   Sun, Jianhe ^b   Hu, Yingyan ^b   Chen, Guangtao ^b   Li, Xingqi ^b  

^a THE AFFILIATED DRUM TOWER HOSPITAL OF NANJING UNIVERSITY MEDICAL SCHOOL   (China)

^b CHINESE PLA GENERAL HOSPITAL   (China)

Author keywords

AQP4; AQP5; Aquaporin 4; Aquaporin 5; Middle ear; Secretory otitis media; SOM; Water balance; Water transport

Indexed keywords

AQUAPORIN 4; AQUAPORIN 5; MESSENGER RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUDITORY TUBE; BLISTER; CONTROLLED STUDY; FLUID BALANCE; HOMEOSTASIS; IMMUNOBLOTTING; MALE; MIDDLE EAR; MIDDLE EAR EFFUSION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SECRETORY OTITIS MEDIA; WATER TRANSPORT; WESTERN BLOTTING; ANIMAL; ELECTROLYTE BALANCE; GENE EXPRESSION; GENETICS; GUINEA PIG; METABOLISM; PATHOLOGY;

ANIMALS; AQUAPORIN 4; AQUAPORIN 5; EAR, MIDDLE; GENE EXPRESSION; GUINEA PIGS; IMMUNOBLOTTING; MALE; OTITIS MEDIA WITH EFFUSION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; WATER-ELECTROLYTE BALANCE;

EID: 75449084326     PISSN: 00016489     EISSN: 16512553     Source Type: Journal    
DOI: 10.3109/00016480902974183     Document Type: Article

References (20)

1. Ophir D, Hahn T, Schattner A, Wallach D, Aviel A. Tumor necrosis factor in middle ear effusion. Arch Otolaryngol Head Neck Surg 1988;/114:/1256-8.
2. Mall M, Grubb BR, Harkema JR, O'Neal WK, Boucher RC. Increased airway epithelial Na+ absorption produces cystic fibrosis-like lung disease in mice. Nat Med 2004;/10:/487-93.
3. Lim DJ, Chun YM, Lee SK, Moon SK, Chang KH, Li JD, et al. Cell biology of tubotympanum in relation to pathogenesis of otitis media a review. Vaccine 2001;/19:/S17-25.
4. King LS, Agre P. Pathophysiology of the aquaporin water channels. Annu Rev Physiol 1996;/58:/619-48.
5. Verkman AS, Mitra AK. Structure and function of aquaporin water channels. Am J Physiol Renal Fluid Electrolyte Physiol 2000;/278:/F13-28.
6. Kumagami H, Loewenheim H, Beitz E, Wild K, Schwartz H, Yamashita K, et al. The effect of anti-diuretic hormone on the endolymphatic sac of the inner ear. Pflugers Arch 1998;/436:/970-5.
7. Zhang X, Yuan YY, Gu WP, Mu JS, Qu Y, Gao HT. Expression and distribution of aquaporin-2 in nasal polyps. Chin J Otorhinolaryngol 2003;/38:/272-4.
8. Stankovic KM, Adams JC, Brown D. Immunolocalization of aquaporin CHIP in the guinea pig inner ear. Am J Physiol 1995;/269(6 Pt 1):/C1450-6.
9. Nielsen S, King LS, Christensen BM, Agre P. Aquaporins in complex tissues. II Subcellular distribution in respiratory and glandular tissues of rat. Am J Physiol 1997;/273(5 Pt 1):/ C1549-61.
10. Kang SH, Chang KH, Ohcho S, Lee HY, Cha K, Moon SK, et al. Expression of water channel proteins (aquaporins) in the rat eustachian tube and middle ear mucosa. Acta Otolaryngol 2007;/127:/687-92.
11. Kuijpers W, Vander Beek JMH, Willart ECT. The effect of experiment tubal obstruction on the middle ear. Acta Otolaryngol 1979;/87:/345-52.
12. Herman P, Cassigena R, Friedlander G, Soler P, Grodet A, Tran Ba Huy P, et al. Middle ear cell line that maintains vectorial electrolyte transport. J Cell Physiol 1993;/154:/615- 22.
13. Choi JY, Son EJ, Kim JL, Lee JH, Park HY, Kim SH, et al. ENaC- and CFTR-dependent ion and fluid transport in human middle ear epithelial cells. Hear Res 2006;/211:/26-32.
14. Hergils L, Magnuson B. Human middle ear gas composition studied by mass spectrometry. Acta Otolaryngol 1990;/110:/ 92-9.
15. Herman P, Portier F, Tran Ba Huy P. Modulation of middle ear epithelial ion transport by oxygen. Clinical relevance. Symposium on Recent Advances on Otitis Media, Copenhagen, 1997.
16. Matthay MA, Flori HR, Conner ER, Ware LB. Alveolar epithelial fluid transport: basic mechanisms and clinical relevance. Proc Assoc Am Physicians 1998;/110:/496-505.
17. Effros RM, Darin C, Jacobs ER, Rogers RA, Krenz G, Schneeberger EE. Water transport and the distribution of aquaporin-1 in pulmonary air spaces. J Appl Physiol 1997;/ 83:/1002-16.
18. Towne JE, Harrod KS, Krane CM, Menon AG. Decreased expression of aquaporin (AQP)1 and AQP5 in mouse lung after acute viral infection. Am J Respir Cell Mol Biol 2000;/ 22:/34-44.
19. Minami S, Kobayashi H, Yamashita A, Yanagita T, Uezono Y, Yokoo H, et al. Selective expression of aquaporin 1, 4 and 5 in the rat middle ear. Hear Res 2001;/158:/51-6.
20. Agre P, Bonhivers M, Borgnia MJ. The aquaporins, blueprints for cellular plumbing systems. J Biol Chem 1998;/273:/ 14659-62.