Effects of vitamin supplementation on PCB (Aroclor 1254)-induced changes in ventral prostatic androgen and estrogen receptors

Endocrine Research

Volumn 30, Issue 3, 2004, Pages 469-480

  Venkataraman, P ^a   Sridhar, M ^a   Dhanammal, Siva ^a   Vijayababu, M R ^a   Arunkumar, A ^a   Srinivasan, N ^a   Arunakaran, J ^a,b  

^a UNIVERSITY OF MADRAS   (India)

^b Dr ALM Postgraduate Institute of Basic Medical Sciences   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA TOCOPHEROL; ANDROGEN RECEPTOR; AROCLOR 1254; ASCORBIC ACID; ESTRADIOL; ESTRADIOL RECEPTOR; ESTROGEN RECEPTOR; LIOTHYRONINE; POLYCHLORINATED BIPHENYL; TESTOSTERONE; THYROTROPIN; THYROXINE; ZINC;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG EXPOSURE; HORMONE BLOOD LEVEL; MALE; NONHUMAN; PRIORITY JOURNAL; PROSTATE VENTRAL LOBE; PROTEIN BLOOD LEVEL; RAT; VITAMIN BLOOD LEVEL; VITAMIN SUPPLEMENTATION; ZINC BLOOD LEVEL;

ANALYSIS OF VARIANCE; ANIMALS; AROCLOR 1254; ASCORBIC ACID; DIETARY SUPPLEMENTS; ENVIRONMENTAL POLLUTANTS; ESTRADIOL; MALE; PROSTATE; RATS; RATS, WISTAR; RECEPTORS, ANDROGEN; RECEPTORS, ESTROGEN; TESTOSTERONE; THYROID HORMONES; VITAMIN E; ZINC;

EID: 7544239188     PISSN: 07435800     EISSN: None     Source Type: Journal    
DOI: 10.1081/ERC-200035959     Document Type: Article

References (33)

1. Evans MS, Noguchi GE, Rice CP. The biomagnification of polychlorinated biphenyls, toxaphene, and DDT compounds in a Lake Michigan offshore food web. Arch Environ Contam Toxicol 1991; 20:87-93.
2. Baird L. Toxic organic chemicals. In: Environmental Chemistry. New York: WH Freeman and Company, 1995:252-274.
3. Kester MHA, Bulduk S, Tibboel D, et al. Potent inhibition of estrogen sulfotransferase by hydroxylated PCB metabolites: a novel pathway explaining the estrogenic activity of PCBs. Endocrinology 2000; 141(5):1897-1900.
4. Hany L, Lilenthal H, Sarasin A, Roth-Harer A, Fastabend A, Dunemann L, Lichtensteiger W, Winneke G. Developmental exposure of rats to a reconstituted PCB mixture or aroclor 1254: effects on organ weights, aromatase activity, sex hormone levels, and sweet preference behavior. Toxicol Appl Pharmacol 1999; 158:231-243.
5. Korach KS, Davis VL, Curtis SW, Bocchinfuso WP. Xenoestrogen and estrogen receptor action. Endocrine Toxicol. 2nd ed. 1997.
6. Sharpe RM, Skakkeback NE. Are estrogens involved in falling sperm count and disorder of the male reproductive tract? Lancet 1993; 343:1345-1392.
7. Gray EL, Ostly J, Marshall R, Andrews. Reproductive and thyroid effects of low-level polychlorinated biphenyl (aroclor1254) exposure. Fund Appl Toxicol 1993; 20:288-294.
8. Anbalagan J, Knagaraj P, Srinivasan N, Aruldhas MM, Arunakaran J. Effect of polychlorinated biphenyl, Aroclor 1254 on rat epididymis. Indian J Med Res 2003; 118:236-242.
9. Hess RA, Bunick D, Bahr J. Oestrogen, its receptors and function in the male reproductive tract - a review. Mol Cell Endocrinol 2001; 178:29-38.
10. Feng P, Liang JY, Li TL, Guan ZX, Zou J, Franklin RB, Costello LC. Zinc induces mitochondria apoptogenesis in prostate cells. Mol Urol 2000; 4:31-36.
11. Fair WR, Wehner N. The prostatic antibacterial factor: identity and significance. In: Marberger H, et al., eds. Prostatic Disease. New York, 1976.
12. Latchoumycandane C, Mathur PP. Effects of vitamin E on reactive oxygen species mediated 2,3,7,8-tetrachlorodi-benzo p dioxin toxicity in rat testis. J Appl Toxicol 2002; 22:345-351.
13. Das UB, Mallick M, Debnath JM, Ghosh D. Protective effect of ascorbic acid on cyclophosphamide induced testicular gamatogenic and androgenic disorders in male rats. Asian J Androl 2002; 4:201-207.
14. Sridhar M, Venkataraman P, Dhanammal S, Arunkumar A, Aruldhas MM, Srinivasan N, Arunakaran J. Impact of polychlorinated biphenyl (Aroclor 1254) and vitamin C on antioxidant system of rat ventral prostate. Asian J Androl 2004; 6(1):19-22.
15. Lall SB, Singh B, Gulatik, Seth SD. Role of nutrition in toxic injury. Indian J Exp Biol 1999; 37:109-116.
16. Subramanian S. Reproductive toxicity of chromium in adult male rats: an endocrine and biochemical study. PhD Thesis, University of Madras, India, 2001.
17. Re G, Badino P, Dacasto M, Di Carlo F, Girardi C. Regulation of uterine estrogen receptors by β adrenergic stimulation in immature rats. J Vet Pharmacol Ther 1993; 16:328-334.
18. Leake RE, Habib F. Androgen receptor assay. In: Green B, Leake RE, eds. Steroid Hormones, A Practical Approach. Oxford: IRL Press Ltd., 1987:76-82.
19. Wong YC, Wang YZ, Lee JS, Tam NN. Changes in serum and tissue zinc levels in the sex hormone induced prostatic carcinogenesis in the noble rat. Tumour Biol 2000; 21(6):328-336.
20. Zar JH. Biostatistical Analysis. Englewood Cliffs, NJ: Prentice Hall Inc., 1974.
21. Schilderman PA, Mass LM, Pachen DM, Dekok TM, Kleinjans JC, Vanschooten FS. Induction of DNA adducts by several polychlorinated biphenyls. Environ Mol Mutagen 2000; 36(2):79-86.
22. Zenick H, Clegg ED, Perrault SD, Klinfelter GR, Gray LE. Assessment of male reproductive toxicity: a risk assessment approach. Principles and Methods of Toxicology. New York: Raven Press, 1994:937-988.
23. Khan A, Thomas P. Disruption of neuroendocrine control of luteinizing hormone secretion by Aroclor 1254 involves inhibition of hypothalamic tryptophan hydroxylase activity. Biol Reprod 2001; 64:955-964.
24. Clark JH, Schrader WT, O'Malley BW. Mechanism of steroid hormone action. In: Wilson JD, Fortee DW, eds. Text Book of Endocrinology. Philadelphia: WB Saunders, 1985:33-75.
25. Asano K, Maruyama S, Usui T, Nariyaki F. Regulation of estrogen receptor alpha and beta expression by testosterone in the rat prostate gland. Endocr J 2003; 50:281-287.
26. Li MH, Zhao YD, Hansen LG. Multiple dose toxicokinetic influence on the estrogenicity of 2,2,4,45,5′-hexachlorobiphenyl. Bull Environ Contam Toxicol 1994; 53:583-590.
27. 2+ buffering and protein kinase C activity in the absence of changes in tyrosine hydroxylase. Toxicol Appl Pharmacol 1998; 153:186-198.
28. Maran RRM, Senthilkumaran B, Udayakumar RCR, Arunakaran J, Aruldhas MM. Thyroidectomy modulates rat prostatic monosaccharides. Int J Androl 2000; 23:156-162.
29. Deshpande UR, Joseph LJ, Patwardhan UN, Samuel AM. Effect of antioxidants (vitamin C, E and turmeric extract) on methimazole induced hypothyroidism in rats. Indian J Exp Biol 2002; 40:735-738.
30. Srivastava A, Chowdhury AR, Setty BS. Zinc content in the epididymis, vas deferens, prostate and seminal vesicles of juvenile rhesus monkey (mecca mulata): effect of androgen and estrogen. Prostate 1984; 5(2):153-158.
31. Karanth S, Yu WH, Walczewska A, Mastronardi CA, McCann SM. Ascorbic acid stimulates gonadotropin release by autocrine action by means of NO. Proc Natl Acad Sci 2001; 98(20):11783-11788.
32. Akazawa N, Milkami S, Kimura S. Effects of vitamin E deficiency on the hormone secretion of the pituitary - gonadal axis of the rat. Tohoku J Exp Med 1987; 152(3):221-229.
33. Wilson JM, Kaye D, Smith WE, Quach HT, Sinha AA, Vatassery GT. Effect of vitamin E deficiency on the growth and secretory function of the rat prostatic complex. Exp Mol Pathol 2003; 74:267-275.