Proteinase-activated receptor pharmacology: Trickier and trickier

British Journal of Pharmacology

Volumn 143, Issue 4, 2004, Pages 441-

  Moffatt, James D ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

Coagulation; Inflammation; Proteinase; Proteinase activated receptor

Indexed keywords

G PROTEIN COUPLED RECEPTOR; PROTEINASE; PROTEINASE ACTIVATED RECEPTOR; PROTEINASE ACTIVATED RECEPTOR 4; PROTEINASE ACTIVATED RECEPTOR AGONIST; UNCLASSIFIED DRUG;

BINDING AFFINITY; BIOASSAY; BLOOD CLOTTING; DRUG RECEPTOR BINDING; INFLAMMATION; INFLAMMATORY DISEASE; PHARMACODYNAMICS; PRIORITY JOURNAL; REVIEW; THROMBOCYTE AGGREGATION; THROMBOSIS;

ANIMALS; HUMANS; PEPTIDE HYDROLASES; RECEPTORS, PROTEINASE-ACTIVATED;

EID: 7544224388     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0705949     Document Type: Review

References (4)

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2. MOFFATT, J.D., PAGE, C.P. & LAURENT, G.J. (2004). Shooting for PARs in lung diseases. Curr. Opin. Pharmacol., 4, 221-229.
3. SAIFEDDINE, M., ROY, S.S., AL-ANI, B., TRIGGLE, C.R. & HOLLENBERG, M.D. (1998). Endothelium-dependent contractile actions of proteinase-activated receptor-2-activating peptides in human umbilical vein: release of a contracting factor via a novel receptor. Br. J. Pharmacol., 125, 1445-1454.
4. STENTON, G.R., NOHARA, O., DERY, R.E., VLIAGOFTIS, H., GILCHRIST, M., JOHRI, A., WALLACE, J.L., HOLLENBERG, M.D., MOQBEL, R. & BEFUS, A.D. (2002). Proteinase-activated receptor (PAR)-1 and -2 agonists induce mediator release from mast cells by pathways distinct from PAR-1 and PAR-2. J. Pharmacol. Exp. Ther., 302, 466-474.