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Volumn 117, Issue 12, 2009, Pages 1860-1866

Changes in urinary arsenic methylation profiles in a 15-year interval after cessation of arsenic ingestion in Southwest Taiwan

Author keywords

Arsenic methylation; Cumulative arsenic exposure; Drinking water

Indexed keywords

ARSENIC; CACODYLIC ACID; METHANEARSONIC ACID;

EID: 75349103065     PISSN: 00916765     EISSN: 15529924     Source Type: Journal    
DOI: 10.1289/ehp.0900560     Document Type: Article
Times cited : (30)

References (65)
  • 2
    • 0003891405 scopus 로고    scopus 로고
    • Atlanta, GA:Agency for Toxic Substances and Disease Registry. Available:, accessed 7 October 2009
    • ATSDR. 2000. Toxicological Profile for Arsenic. Atlanta, GA:Agency for Toxic Substances and Disease Registry. Available: http://www.atsdr.cdc.gov/ toxprofiles/tp2. html#bookmark06 [accessed 7 October 2009].
    • (2000) Toxicological Profile for Arsenic
  • 3
    • 0023612547 scopus 로고
    • Study of factors influencing the in vivo methylation of inorganic arsenic in rats
    • Buchet JP, Lauwerys R. 1987. Study of factors influencing the in vivo methylation of inorganic arsenic in rats. Toxicol Appl Pharmacol 91:65-74.
    • (1987) Toxicol Appl Pharmacol , vol.91 , pp. 65-74
    • Buchet, J.P.1    Lauwerys, R.2
  • 5
    • 0019485360 scopus 로고
    • Urinary excretion of inorganic arsenic and its metabolites after repeated ingestion of sodium metaarsenite by volunteers
    • Buchet JP, Lauwerys R, Roels H. 1981. Urinary excretion of inorganic arsenic and its metabolites after repeated ingestion of sodium metaarsenite by volunteers. Int Arch Occup Environ Health 48:111-118.
    • (1981) Int Arch Occup Environ Health , vol.48 , pp. 111-118
    • Buchet, J.P.1    Lauwerys, R.2    Roels, H.3
  • 7
    • 0026498334 scopus 로고
    • Cancer potential in liver, lung, bladder and kidney due to ingested inorganic arsenic in drinking water
    • Chen CJ, Chen CW, Wu MM, Kuo TL. 1992. Cancer potential in liver, lung, bladder and kidney due to ingested inorganic arsenic in drinking water. Br J Cancer 66:888-892.
    • (1992) Br J Cancer , vol.66 , pp. 888-892
    • Chen, C.J.1    Chen, C.W.2    Wu, M.M.3    Kuo, T.L.4
  • 8
    • 0022369570 scopus 로고
    • Malignant neoplasms among residents of a blackfoot disease-endemic area in Taiwan: High-arsenic artesian well water and cancers
    • Chen CJ, Chuang YC, Lin TM, Wu HY. 1985. Malignant neoplasms among residents of a blackfoot disease-endemic area in Taiwan: high-arsenic artesian well water and cancers. Cancer Res 45:5895-5899.
    • (1985) Cancer Res , vol.45 , pp. 5895-5899
    • Chen, C.J.1    Chuang, Y.C.2    Lin, T.M.3    Wu, H.Y.4
  • 10
    • 33847388077 scopus 로고    scopus 로고
    • Arsenic exposure from drinking water, dietary intakes of B vitamins and folate, and risk of high blood pressure in Bangladesh: A population-based, cross-sectional study
    • Chen Y, Factor-Litvak P, Howe GR, Graziano JH, Brandt-Rauf P, Parvez F, et al. 2007. Arsenic exposure from drinking water, dietary intakes of B vitamins and folate, and risk of high blood pressure in Bangladesh: a population-based, cross-sectional study. Am J Epidemiol 165:541-552.
    • (2007) Am J Epidemiol , vol.165 , pp. 541-552
    • Chen, Y.1    Factor-Litvak, P.2    Howe, G.R.3    Graziano, J.H.4    Brandt-Rauf, P.5    Parvez, F.6
  • 13
    • 0037288844 scopus 로고    scopus 로고
    • Pattern of excretion of arsenic compounds [arsenite, arsenate, MMA(V), DMA(V)] in urine of children compared to adults from an arsenic exposed area in Bangladesh
    • Chowdhury UK, Rahman MM, Sengupta MK, Lodh D, Chanda CR, Roy S, et al. 2003. Pattern of excretion of arsenic compounds [arsenite, arsenate, MMA(V), DMA(V)] in urine of children compared to adults from an arsenic exposed area in Bangladesh. J Environ Sci Health Part A Toxic/Hazard Subst Environ Eng 38:87-113.
    • (2003) J Environ Sci Health Part A Toxic/Hazard Subst Environ Eng , vol.38 , pp. 87-113
    • Chowdhury, U.K.1    Rahman, M.M.2    Sengupta, M.K.3    Lodh, D.4    Chanda, C.R.5    Roy, S.6
  • 14
    • 0036059830 scopus 로고    scopus 로고
    • Family correlations of arsenic methyla tion patterns in children and parents exposed to high concentrations of arsenic in drinking water
    • Chung JS, Kalman DA, Moore LE, Kosnett MJ, Arroyo AP, Beeris M, et al. 2002. Family correlations of arsenic methyla tion patterns in children and parents exposed to high concentrations of arsenic in drinking water. Environ Health Perspect 110:729-733.
    • (2002) Environ Health Perspect , vol.110 , pp. 729-733
    • Chung, J.S.1    Kalman, D.A.2    Moore, L.E.3    Kosnett, M.J.4    Arroyo, A.P.5    Beeris, M.6
  • 15
    • 0031928806 scopus 로고    scopus 로고
    • Metabolism of inorganic arsenic in children with chronic high arsenic exposure in northern Argentina
    • Concha G, Nermell B, Vahter MV. 1998. Metabolism of inorganic arsenic in children with chronic high arsenic exposure in northern Argentina. Environ Health Perspect 106:355-359.
    • (1998) Environ Health Perspect , vol.106 , pp. 355-359
    • Concha, G.1    Nermell, B.2    Vahter, M.V.3
  • 17
    • 50349083509 scopus 로고    scopus 로고
    • Interplay between cellular methyl metabolism and adaptive efflux during oncogenic transformation from chronic arsenic exposure in human cells
    • Coppin JF, Qu W, Waalkes MP. 2008. Interplay between cellular methyl metabolism and adaptive efflux during oncogenic transformation from chronic arsenic exposure in human cells. J Biol Chem 283:19342-19350.
    • (2008) J Biol Chem , vol.283 , pp. 19342-19350
    • Coppin, J.F.1    Qu, W.2    Waalkes, M.P.3
  • 18
    • 2042463242 scopus 로고
    • A case of chronic arsenical poisoning; examination of tissue samples by activation analysis
    • Dewar WA, Lenihan JM. 1956. A case of chronic arsenical poisoning; examination of tissue samples by activation analysis. Scott Med J 1:236-238.
    • (1956) Scott Med J , vol.1 , pp. 236-238
    • Dewar, W.A.1    Lenihan, J.M.2
  • 19
    • 57149107969 scopus 로고    scopus 로고
    • Ethnic differences in five intronic polymorphisms associated with arsenic metabolism within human arsenic (+3 oxidation state) methyltransferase (AS3MT) gene
    • Fujihara J, Fujii Y, Agusa T, Kunito T, Yasuda T, Moritani T, et al. 2009. Ethnic differences in five intronic polymorphisms associated with arsenic metabolism within human arsenic (+3 oxidation state) methyltransferase (AS3MT) gene. Toxicol Appl Pharmacol 234:41-46.
    • (2009) Toxicol Appl Pharmacol , vol.234 , pp. 41-46
    • Fujihara, J.1    Fujii, Y.2    Agusa, T.3    Kunito, T.4    Yasuda, T.5    Moritani, T.6
  • 20
    • 47849088995 scopus 로고    scopus 로고
    • Asian specific low mutation frequencies of the M287T polymorphism in the human arsenic (+3 oxidation state) methyltransferase (AS3MT) gene
    • Fujihara J, Soejima M, Koda Y, Kunito T, Takeshita H. 2008. Asian specific low mutation frequencies of the M287T polymorphism in the human arsenic (+3 oxidation state) methyltransferase (AS3MT) gene. Mutat Res 654:158-161.
    • (2008) Mutat Res , vol.654 , pp. 158-161
    • Fujihara, J.1    Soejima, M.2    Koda, Y.3    Kunito, T.4    Takeshita, H.5
  • 24
    • 0036214617 scopus 로고    scopus 로고
    • Caveats in hair analysis in chronic arsenic poisoning
    • Hindmarsh JT. 2002. Caveats in hair analysis in chronic arsenic poisoning. Clin Biochem 35:1-11.
    • (2002) Clin Biochem , vol.35 , pp. 1-11
    • Hindmarsh, J.T.1
  • 25
    • 0030474176 scopus 로고    scopus 로고
    • Arsenic methylation patterns before and after changing from high to lower concentrations of arsenic in drinking water
    • Hopenhayn-Rich C, Biggs ML, Kalman DA, Moore LE, Smith AH. 1996a. Arsenic methylation patterns before and after changing from high to lower concentrations of arsenic in drinking water. Environ Health Perspect 104:1200-1207.
    • (1996) Environ Health Perspect , vol.104 , pp. 1200-1207
    • Hopenhayn-Rich, C.1    Biggs, M.L.2    Kalman, D.A.3    Moore, L.E.4    Smith, A.H.5
  • 28
    • 0037036583 scopus 로고    scopus 로고
    • Urinary arsenic speciation in subjects with or without restriction from seafood dietary intake
    • Hsueh YM, Hsu MK, Chiou HY, Yang MH, Huang CC, Chen CJ. 2002. Urinary arsenic speciation in subjects with or without restriction from seafood dietary intake. Toxicol Lett 133:83-91.
    • (2002) Toxicol Lett , vol.133 , pp. 83-91
    • Hsueh, Y.M.1    Hsu, M.K.2    Chiou, H.Y.3    Yang, M.H.4    Huang, C.C.5    Chen, C.J.6
  • 29
    • 0032563083 scopus 로고    scopus 로고
    • Urinary levels of inorganic and organic arsenic metabolites among residents in an arseniasis-hyperendemic area in Taiwan
    • Hsueh YM, Huang YL, Huang CC, Wu WL, Chen HM, Yang MH, et al. 1998. Urinary levels of inorganic and organic arsenic metabolites among residents in an arseniasis-hyperendemic area in Taiwan. J Toxicol Environ Health A 54:431-444.
    • (1998) J Toxicol Environ Health A , vol.54 , pp. 431-444
    • Hsueh, Y.M.1    Huang, Y.L.2    Huang, C.C.3    Wu, W.L.4    Chen, H.M.5    Yang, M.H.6
  • 30
    • 12244303641 scopus 로고    scopus 로고
    • Determinants of inorganic arsenic methylation capability among residents of the Lanyang Basin, Taiwan: Arsenic and selenium exposure and alcohol consumption
    • Hsueh YM, Ko YF, Huang YK, Chen HW, Chiou HY, Huang YL, et al. 2003. Determinants of inorganic arsenic methylation capability among residents of the Lanyang Basin, Taiwan: arsenic and selenium exposure and alcohol consumption. Toxicol Lett 137:49-63.
    • (2003) Toxicol Lett , vol.137 , pp. 49-63
    • Hsueh, Y.M.1    Ko, Y.F.2    Huang, Y.K.3    Chen, H.W.4    Chiou, H.Y.5    Huang, Y.L.6
  • 31
    • 52449108128 scopus 로고    scopus 로고
    • Arsenic exposure, urinary arsenic speciation, and the incidence of urothelial carcinoma: A twelve-year follow-up study
    • Huang YK, Huang YL, Hsueh YM, Yang MH, Wu MM, Chen SY, et al. 2008. Arsenic exposure, urinary arsenic speciation, and the incidence of urothelial carcinoma: a twelve-year follow-up study. Cancer Causes Control 19(8):829-839.
    • (2008) Cancer Causes Control , vol.19 , Issue.8 , pp. 829-839
    • Huang, Y.K.1    Huang, Y.L.2    Hsueh, Y.M.3    Yang, M.H.4    Wu, M.M.5    Chen, S.Y.6
  • 32
    • 33846620625 scopus 로고    scopus 로고
    • Arsenic methylation capability and hypertension risk in subjects living in arseniasis-hyperendemic areas in southwestern Taiwan
    • Huang YK, Tseng CH, Huang YL, Yang MH, Chen CJ, Hsueh YM. 2007. Arsenic methylation capability and hypertension risk in subjects living in arseniasis-hyperendemic areas in southwestern Taiwan. Toxicol Appl Pharmacol 218:135-142.
    • (2007) Toxicol Appl Pharmacol , vol.218 , pp. 135-142
    • Huang, Y.K.1    Tseng, C.H.2    Huang, Y.L.3    Yang, M.H.4    Chen, C.J.5    Hsueh, Y.M.6
  • 34
    • 0019298910 scopus 로고
    • Some Metals and Metallic Compounds
    • IARC International Agency for Research on Cancer
    • IARC (International Agency for Research on Cancer). 1980. Some Metals and Metallic Compounds. IARC Monogr Eval Carcinog Risk Hum 23:1-438.
    • (1980) IARC Monogr Eval Carcinog Risk Hum , vol.23 , pp. 1-438
  • 35
    • 53649083711 scopus 로고    scopus 로고
    • Kenyon EM, Hughes MF, Adair BM, Highfill JH, Crecelius EA, Clewell HJ, et al. 2008. Tissue distribution and urinary excretion of inorganic arsenic and its methylated metabolites in C57BL6 mice following subchronic exposure to arsenate in drinking water. Toxicol Appl Pharmacol 232:448-455; doi:10.1016/j.taap.2008.07.018 [Online 28 July 2008].
    • Kenyon EM, Hughes MF, Adair BM, Highfill JH, Crecelius EA, Clewell HJ, et al. 2008. Tissue distribution and urinary excretion of inorganic arsenic and its methylated metabolites in C57BL6 mice following subchronic exposure to arsenate in drinking water. Toxicol Appl Pharmacol 232:448-455; doi:10.1016/j.taap.2008.07.018 [Online 28 July 2008].
  • 36
    • 0002883307 scopus 로고
    • Arsenic content of artesian well water in endemic area of chronic arsenic poisoning
    • Kuo TL. 1964. Arsenic content of artesian well water in endemic area of chronic arsenic poisoning. Rep Inst Pathol Natl Taiwan Univ 20:7-13.
    • (1964) Rep Inst Pathol Natl Taiwan Univ , vol.20 , pp. 7-13
    • Kuo, T.L.1
  • 38
    • 0028350137 scopus 로고
    • Human urinary arsenic excretion after one-time ingestion of seaweed, crab, and shrimp
    • Le XC, Cullen WR, Reimer KJ. 1994. Human urinary arsenic excretion after one-time ingestion of seaweed, crab, and shrimp. Clin Chem 40:617-624.
    • (1994) Clin Chem , vol.40 , pp. 617-624
    • XC, L.1    Cullen, W.R.2    Reimer, K.J.3
  • 39
    • 0035056158 scopus 로고    scopus 로고
    • Identification of dimethylarsinous and monomethylarsonous acids in human urine of the arsenic-affected areas in West Bengal, India
    • Mandal BK, Ogra Y, Suzuki KT. 2001. Identification of dimethylarsinous and monomethylarsonous acids in human urine of the arsenic-affected areas in West Bengal, India. Chem Res Toxicol 14:371-378.
    • (2001) Chem Res Toxicol , vol.14 , pp. 371-378
    • Mandal, B.K.1    Ogra, Y.2    Suzuki, K.T.3
  • 40
    • 0020001286 scopus 로고
    • Intracellular interaction and biotransformation of arsenite in rats and rabbits
    • Marafante E, Bertolero F, Edel J, Pietra R, Sabbioni E. 1982. Intracellular interaction and biotransformation of arsenite in rats and rabbits. Sci Total Environ 24:27-39.
    • (1982) Sci Total Environ , vol.24 , pp. 27-39
    • Marafante, E.1    Bertolero, F.2    Edel, J.3    Pietra, R.4    Sabbioni, E.5
  • 41
    • 9144222018 scopus 로고    scopus 로고
    • Polymorphisms in the human monomethylarsonic acid (MMA V) reductase/hGSTO1 gene and changes in urinary arsenic profiles
    • Marnell LL, Garcia-Vargas GG, Chowdhury UK, Zakharyan RA, Walsh B, Avram MD, et al. 2003. Polymorphisms in the human monomethylarsonic acid (MMA V) reductase/hGSTO1 gene and changes in urinary arsenic profiles. Chem Res Toxicol 16:1507-1513.
    • (2003) Chem Res Toxicol , vol.16 , pp. 1507-1513
    • Marnell, L.L.1    Garcia-Vargas, G.G.2    Chowdhury, U.K.3    Zakharyan, R.A.4    Walsh, B.5    Avram, M.D.6
  • 42
    • 4344585303 scopus 로고    scopus 로고
    • Arsenic drinking water exposure and urinary excretion among adults in the Yaqui Valley, Sonora, Mexico
    • Meza MM, Kopplin MJ, Burgess JL, Gandolfi AJ. 2004. Arsenic drinking water exposure and urinary excretion among adults in the Yaqui Valley, Sonora, Mexico. Environ Res 96:119-126.
    • (2004) Environ Res , vol.96 , pp. 119-126
    • Meza, M.M.1    Kopplin, M.J.2    Burgess, J.L.3    Gandolfi, A.J.4
  • 43
    • 0344994575 scopus 로고    scopus 로고
    • Age-dependent changes of the kidneys: Pharmacological implications
    • Mühlberg W, Platt D. 1999. Age-dependent changes of the kidneys: pharmacological implications. Gerontology 45:243-253.
    • (1999) Gerontology , vol.45 , pp. 243-253
    • Mühlberg, W.1    Platt, D.2
  • 44
    • 0036226578 scopus 로고    scopus 로고
    • Evidence for induction of oxidative stress caused by chronic exposure of Chinese residents to arsenic contained in drinking water
    • Pi J, Yamauchi H, Kumagai Y, Sun G, Yoshida T, Aikawa H, et al. 2002. Evidence for induction of oxidative stress caused by chronic exposure of Chinese residents to arsenic contained in drinking water. Environ Health Perspect 110:331-336.
    • (2002) Environ Health Perspect , vol.110 , pp. 331-336
    • Pi, J.1    Yamauchi, H.2    Kumagai, Y.3    Sun, G.4    Yoshida, T.5    Aikawa, H.6
  • 45
  • 47
    • 67649206115 scopus 로고    scopus 로고
    • Schläwicke Engström K, Nermell B, Concha G, Stromberg U, Vahter M, Broberg K. 2009. Arsenic metabolism is influenced by polymorphisms in genes involved in one-carbon metabolism and reduction reactions. Mutat Res 667(1-2):4-14.doi:10.1016/j.mrfmmm.2008.07.003 [Online 10 July 2009].
    • Schläwicke Engström K, Nermell B, Concha G, Stromberg U, Vahter M, Broberg K. 2009. Arsenic metabolism is influenced by polymorphisms in genes involved in one-carbon metabolism and reduction reactions. Mutat Res 667(1-2):4-14.doi:10.1016/j.mrfmmm.2008.07.003 [Online 10 July 2009].
  • 48
    • 22544482100 scopus 로고    scopus 로고
    • Schmuck EM, Board Whitbread AK, Tetlow N, Cavanaugh JA, Blackburn AC, et al. 2005. Characterization of the monomethylarsonate reductase and dehydroascorbate reductase activities of omega class glutathione transferase variants: implications for arsenic metabolism and the age-at-onset of Alzheimer's and Parkinson's diseases. Pharmacogenet Genomics 15:493-501.
    • Schmuck EM, Board PG, Whitbread AK, Tetlow N, Cavanaugh JA, Blackburn AC, et al. 2005. Characterization of the monomethylarsonate reductase and dehydroascorbate reductase activities of omega class glutathione transferase variants: implications for arsenic metabolism and the age-at-onset of Alzheimer's and Parkinson's diseases. Pharmacogenet Genomics 15:493-501.
  • 49
    • 33646846988 scopus 로고    scopus 로고
    • Arsenic methylation and bladder cancer risk in case-control studies in Argentina and the United States
    • Steinmaus C, Bates MN, Yuan Y, Kalman D, Atallah R, Rey OA, et al. 2006. Arsenic methylation and bladder cancer risk in case-control studies in Argentina and the United States. J Occup Environ Med 48:478-488.
    • (2006) J Occup Environ Med , vol.48 , pp. 478-488
    • Steinmaus, C.1    Bates, M.N.2    Yuan, Y.3    Kalman, D.4    Atallah, R.5    Rey, O.A.6
  • 51
    • 0033841975 scopus 로고    scopus 로고
    • Comparative toxicity of trivalent and pentavalent inorganic and methylated arsenicals in rat and human cells
    • Styblo M, Del Razo LM, Vega L, Germolec DR, LeCluyse EL, Hamilton GA, et al. 2000. Comparative toxicity of trivalent and pentavalent inorganic and methylated arsenicals in rat and human cells. Arch Toxicol 74:289-299.
    • (2000) Arch Toxicol , vol.74 , pp. 289-299
    • Styblo, M.1    Del Razo, L.M.2    Vega, L.3    Germolec, D.R.4    LeCluyse, E.L.5    Hamilton, G.A.6
  • 52
    • 0034759637 scopus 로고    scopus 로고
    • The cellular metabolism and systemic toxicity of arsenic
    • Thomas DJ, Styblo M, Lin S. 2001. The cellular metabolism and systemic toxicity of arsenic. Toxicol Appl Pharmacol 176:127-144.
    • (2001) Toxicol Appl Pharmacol , vol.176 , pp. 127-144
    • Thomas, D.J.1    Styblo, M.2    Lin, S.3
  • 53
    • 22544460259 scopus 로고    scopus 로고
    • Arsenic exposure, urinary arsenic speciation, and peripheral vascular disease in blackfoot disease-hyperendemic villages in Taiwan
    • Tseng CH, Huang YK, Huang YL, Chung CJ, Yang MH, Chen CJ, et al. 2005. Arsenic exposure, urinary arsenic speciation, and peripheral vascular disease in blackfoot disease-hyperendemic villages in Taiwan. Toxicol Appl Pharmacol 206:299-308.
    • (2005) Toxicol Appl Pharmacol , vol.206 , pp. 299-308
    • Tseng, C.H.1    Huang, Y.K.2    Huang, Y.L.3    Chung, C.J.4    Yang, M.H.5    Chen, C.J.6
  • 54
    • 0032604253 scopus 로고    scopus 로고
    • Methylation of inorganic arsenic in different mammalian species and population groups
    • Vahter M. 1999. Methylation of inorganic arsenic in different mammalian species and population groups. Sci Prog 82:69-88.
    • (1999) Sci Prog , vol.82 , pp. 69-88
    • Vahter, M.1
  • 55
    • 12744278865 scopus 로고    scopus 로고
    • Genetic polymorphism in the biotransformation of inorganic arsenic and its role in toxicity
    • Vahter M. 2000. Genetic polymorphism in the biotransformation of inorganic arsenic and its role in toxicity. Toxicol Lett 112-113:209-217.
    • (2000) Toxicol Lett , vol.112-113 , pp. 209-217
    • Vahter, M.1
  • 56
    • 37149027303 scopus 로고    scopus 로고
    • Interactions between arsenic-induced toxicity and nutrition in early life
    • Vahter ME. 2007. Interactions between arsenic-induced toxicity and nutrition in early life. J Nutr 137:2798-2804.
    • (2007) J Nutr , vol.137 , pp. 2798-2804
    • Vahter, M.E.1
  • 58
    • 0019230817 scopus 로고
    • Metabolism of 74As-labeled trivalent and pentavalent inorganic arsenic in mice
    • Vahter M, Norin H. 1980. Metabolism of 74As-labeled trivalent and pentavalent inorganic arsenic in mice. Environ Res 21:446-457.
    • (1980) Environ Res , vol.21 , pp. 446-457
    • Vahter, M.1    Norin, H.2
  • 60
    • 0035341194 scopus 로고    scopus 로고
    • Differential effects of trivalent and pentavalent arsenicals on cell proliferation and cytokine secretion in normal human epidermal keratinocytes
    • Vega L, Styblo M, Patterson R, Cullen W, Wang C, Germolec D. 2001. Differential effects of trivalent and pentavalent arsenicals on cell proliferation and cytokine secretion in normal human epidermal keratinocytes. Toxicol Appl Pharmacol 172:225-232.
    • (2001) Toxicol Appl Pharmacol , vol.172 , pp. 225-232
    • Vega, L.1    Styblo, M.2    Patterson, R.3    Cullen, W.4    Wang, C.5    Germolec, D.6
  • 61
    • 33646365629 scopus 로고    scopus 로고
    • Human arsenic methyltransferase (AS3MT) pharmacogenetics: Gene resequencing and functional genomics studies
    • Wood TC, Salavaggione OE, Mukherjee B, Wang L, Klumpp AF, Thomae BA, et al. 2006. Human arsenic methyltransferase (AS3MT) pharmacogenetics: gene resequencing and functional genomics studies. J Biol Chem 281:7364-7373.
    • (2006) J Biol Chem , vol.281 , pp. 7364-7373
    • Wood, T.C.1    Salavaggione, O.E.2    Mukherjee, B.3    Wang, L.4    Klumpp, A.F.5    Thomae, B.A.6
  • 62
    • 0003034864 scopus 로고
    • Epidemiologic studies on blackfoot disease: I. Prevalence and incidence of the disease by age, sex, occupation and geographical distribution
    • Wu HY, Chen KP, Tseng WP, Hsu CL. 1961. Epidemiologic studies on blackfoot disease: I. Prevalence and incidence of the disease by age, sex, occupation and geographical distribution. Mem College Med Natl Taiwan Univ 7:33-50.
    • (1961) Mem College Med Natl Taiwan Univ , vol.7 , pp. 33-50
    • Wu, H.Y.1    Chen, K.P.2    Tseng, W.P.3    Hsu, C.L.4
  • 63
    • 0024802195 scopus 로고
    • Dose-response relation between arsenic concentration in well water and mortality from cancers and vascular diseases
    • Wu MM, Kuo TL, Hwang YH, Chen CJ. 1989. Dose-response relation between arsenic concentration in well water and mortality from cancers and vascular diseases. Am J Epidemiol 130:1123-1132.
    • (1989) Am J Epidemiol , vol.130 , pp. 1123-1132
    • Wu, M.M.1    Kuo, T.L.2    Hwang, Y.H.3    Chen, C.J.4
  • 64
    • 0021924256 scopus 로고
    • Metabolism and excretion of orally administrated arsenic trioxide in the hamster
    • Yamauchi H, Yamamura Y. 1985. Metabolism and excretion of orally administrated arsenic trioxide in the hamster. Toxicology 34:113-121.
    • (1985) Toxicology , vol.34 , pp. 113-121
    • Yamauchi, H.1    Yamamura, Y.2


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