Preventive effects of different drugs on intestinal damage induced by non-steroidal antiinflammatory drugs in rats

World Chinese Journal of Digestology

Volumn 17, Issue 31, 2009, Pages 3244-3248

  Fang, Li ^a   Lv, Bin ^a   Meng, Li Na ^a   Zhang, Shuo ^a   Wu, Wei Feng ^a  

^a ZHEJIANG CHINESE MEDICAL UNIVERSITY   (China)

Author keywords

Different drugs; Intestinal damage; Non steroidal anti inflammatory drug

Indexed keywords

DICLOFENAC; ESOMEPRAZOLE; GEFARNATE; METRONIDAZOLE; NONSTEROID ANTIINFLAMMATORY AGENT; TEPRENONE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; HISTOLOGY; INTESTINE INJURY; INTESTINE MUCOSA; MALE; NONHUMAN; PROPHYLAXIS; RAT;

EID: 75349102717     PISSN: 10093079     EISSN: None     Source Type: Journal    
DOI: 10.11569/wcjd.v17.i31.3244     Document Type: Article

References (13)

1. Chinese source
2. Griffin MR. Epidemiology of nonsteroidal antiinflammatory drug-associated gastrointestinal injury. Am J Med 1998; 104: 23S-29S; discussion 41S-42S
3. Yamada T, Deitch E, Specian RD, Perry MA, Sartor RB, Grisham MB. Mechanisms of acute and chronic intestinal inflammation induced by indomethacin. Inflammation 1993; 17: 641-662
4. Zhu F, Qian J, Pan G. [The establishment of TNBSinduced experimental colitis] Zhongguo Yixue Kexueyuan Xuebao 1998; 20: 271-278
5. Chiu CJ, McArdle AH, Brown R, Scott HJ, Gurd FN. Intestinal mucosal lesion in low-flow states. I. A morphological, hemodynamic, and metabolic reappraisal. Arch Surg 1970; 101: 478-483
6. Chinese source
7. Chinese source
8. Hawkey CJ. Nonsteroidal anti-inflammatory drug gastropathy. Gastroenterology 2000; 119: 521-535
9. László A, Kelly JP, Kaufman DE, Sheehan JE, Rétsági G, Wiholm BE, Koff RS, Sundström A, Shapiro S. Clinical aspects of upper gastrointestinal bleeding associated with the use of nonsteroidal antiinflammatory drugs. Am J Gastroenterol 1998; 93: 721-725
10. Ohta Y, Kobayashi T, Inui K, Yoshino J, Kitagawa A, Nakazawa S. Preventive effect of teprenone on acute gastric mucosal lesion progression in compound 48/80-treated rats. Eur J Pharmacol 2004; 487: 223-232
11. Takano T, Tsutsumi S, Tomisato W, Hoshino T, Tsuchiya T, Mizushima T. Geranylgeranylacetone protects guinea pig gastric mucosal cells from gastric stressor-induced apoptosis. Dig Dis Sci 2002; 47: 1546-1553
12. Yanagawa A, Endo T. Retrospective 10 years large scale evaluation of gastrointestinal lesion associated with NSAIDs in 9,084 patients with rheumatoid arthritis aud osteoarthritis and prophylactic efficary of teprenone against NSAIDs AGML. Inflamm Regen 2001; 21: 149-153
13. Fortun PJ, Hawkey CJ. Nonsteroidal antiinflammatory drugs and the small intestine. Curr Opin Gastroenterol 2005; 21: 169-175