Simultaneous HPLC determination of 14 tricyclic antidepressants and metabolites in human plasma

Journal of Separation Science

Volumn 33, Issue 1, 2010, Pages 23-30

  Mercolini, Laura ^a   Mandrioli, Roberto ^a   Finizio, Giulia ^a   Boncompagni, Giancarlo ^b   Raggi, Maria Augusta ^a  

^a UNIVERSITY OF BOLOGNA   (Italy)

^b UNIVERSITY OF BOLOGNA   (Italy)

Author keywords

HPLC UV; Human plasma; SPE; Tricyclic antidepressants

Indexed keywords

ANALYTES; EXTRACTION YIELD; HPLC METHOD; HPLC-UV; HUMAN PLASMAS; INTERNAL STANDARDS; MOBILE PHASE; MONO-THERAPY; PHOSPHATE BUFFERS; PLASMA SAMPLES; POLYPHARMACY; PRE-TREATMENT; REVERSED-PHASE COLUMNS; SIMULTANEOUS DETERMINATIONS; THERAPEUTIC DRUG MONITORING; TRICYCLIC ANTIDEPRESSANTS; UV DETECTOR;

DRUG THERAPY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; METABOLISM; METABOLITES; PATIENT MONITORING; PLASMA (HUMAN); PLASMAS; SOLAR RADIATION;

HIGH PRESSURE LIQUID CHROMATOGRAPHY;

AMITRIPTYLINE; AMITRIPTYLINOXIDE; AMOXAPINE; CLOMIPRAMINE; DIBENZEPIN; DRUG METABOLITE; IMIPRAMINE; LOXAPINE; MAPROTILINE; NORCLOMIPRAMINE; NORTRIPTYLINE; PHOSPHATE BUFFERED SALINE; PROTRIPTYLINE; TRICYCLIC ANTIDEPRESSANT AGENT;

ACCURACY; ARTICLE; COLUMN CHROMATOGRAPHY; CONTROLLED STUDY; DRUG ANALYSIS; DRUG BLOOD LEVEL; DRUG ISOLATION; DRUG MONITORING; DRUG STRUCTURE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; PH; POLYPHARMACY; PRIORITY JOURNAL; PURIFICATION; SAMPLE; SATISFACTION; STANDARD; ULTRAVIOLET RADIATION;

ANTIDEPRESSIVE AGENTS, TRICYCLIC; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DEPRESSION; HUMANS; LIMIT OF DETECTION; MOLECULAR STRUCTURE; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY;

EID: 75349093750     PISSN: 16159306     EISSN: 16159314     Source Type: Journal    
DOI: 10.1002/jssc.200900493     Document Type: Article

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