To heal or not to heal: Predictive value of in vivo reflectance-mode confocal microscopy in assessing healing course of human burn wounds

Journal of Burn Care and Research

Volumn 30, Issue 6, 2009, Pages 1007-1012

  Altintas, Ahmet A ^a   Guggenheim, Merlin ^b   Altintas, Mehmet A ^c   Amini, Peymaneh ^a   Stasch, Tilman ^a   Spilker, Gerald ^a  

^a UNIVERSITY OF WITTEN HERDECKE   (Germany)

^b UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^c LEIBNIZ UNIVERSITY HANNOVER   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; BASEMENT MEMBRANE; BLOOD FLOW; BURN; CLINICAL ARTICLE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; EVALUATION; FEMALE; HUMAN; HUMAN CELL; IN VIVO STUDY; INFLAMMATORY CELL; MALE; MEDICAL DECISION MAKING; MICROCIRCULATION; MORPHOMETRICS; PREDICTIVE VALIDITY; QUANTITATIVE ANALYSIS; REFLECTANCE MODE CONFOCAL MICROSCOPY; RETROSPECTIVE STUDY; THICKNESS; WOUND HEALING; ANALYSIS OF VARIANCE; NONPARAMETRIC TEST; PATHOLOGY; PHYSIOLOGY; PREDICTION AND FORECASTING; SKIN; VASCULARIZATION;

ADULT; ANALYSIS OF VARIANCE; BURNS; FEMALE; HUMANS; MALE; MICROCIRCULATION; MICROSCOPY, CONFOCAL; PREDICTIVE VALUE OF TESTS; RETROSPECTIVE STUDIES; SKIN; STATISTICS, NONPARAMETRIC; WOUND HEALING;

EID: 75349093222     PISSN: 1559047X     EISSN: 15590488     Source Type: Journal    
DOI: 10.1097/BCR.0b013e3181bfb810     Document Type: Article

References (26)

1. Green M, Holloway GA, Heimbach DM. Laser Doppler monitoring of microcirculatory changes in acute burn wounds. J Burn Care Rehabil 1988;9:57-62.
2. Jackson DM. [The diagnosis of the depth of burning.]. Br J Surg 1953;40:588-596
3. Robson MC, Kucan JO, Paik KI, Eriksson E. Prevention of dermal ischemia after thermal injury. Arch Surg 1978;113: 621-625
4. Heimbach D, Mann R, Engrav L. Evaluation of the burn wound management decision. In: Herndon DN, editor. Total burn care. Philadelphia:WB Saunders Company; 1996. p. 81-86
5. Knabl JS, Bauer W, Andel H, et al.. Progression of burn wound depth by systemical application of a vasoconstrictor: an experimental study with a new rabbit model. Burns 1999; 25:715-721
6. Riordan CL, McDonough M, Davidson JM, et al.. Noncontact laser Doppler imaging in burn depth analysis of the extremities. J Burn Care Rehabil 2003;24:177-186
7. Mileski WJ, Atiles L, Purdue G, et al.. Serial measurements increase the accuracy of laser Doppler assessment of burn wounds. J Burn Care Rehabil 2003;24:187-191
8. Kao CC, Garner WL. Acute burns. Plast Reconstr Surg 2000; 101:2482-93; discussion 2494.
9. Zawacki, BE. The natural history of reversible burn injury. Surg Gynecol Obstet 1974;139:867-872
10. Harada T, Izaki S, Tsutsumi H, Kobayashi M, Kitamura K. Apoptosis of hair follicle cells in the second-degree burn wound unders hypernatremic conditions. Burns 1998;24: 464-469
11. Tyler MP, Watts AM, Perry ME, Roberts AH, McGrouther DA. Dermal cellular inflammation in burns. An insight into the function of dermal microvascular anatomy. Burns 2001; 27:433-438
12. Sezer AD, Hatipoǧlu F, Cevher E, Ogcaron;urtan Z, BaşAL, Akbuǧa J. Chitosan film containing fucoidan as a wound dressing for dermal burn healing: preparation and in vitro/in vivo evaluation. AAPS PharmSciTech, 2007;8:Article 39.
13. Agaiby AD, Dyson M. Immuno-inflammatory cell dynamics during cutaneous wound healing. J Anat 1999;195:531-542
14. Rajadhyaksha M, González S, Zavislan JM, Anderson RR, Webb RH. In vivo confocal scanning laser microscopy of human skin II: advances in instrumentation and comparison with histology. J Invest Dermatol 1999;113:293-303.
15. Gerger A, Koller S, Kern T, et al.. Konfokale in-vivo Laserscanmikroskopie in der Melanomdiagnostik. Akt Dermatol 2004;30:345-54. (Jahrestagung der Arbeitsgemeinschaft Dermatologische Forschung, München, October 21-23, 2004).
16. Gambichler T, Sauermann K, Altintas MA, et al.. Effects of repeated sunbed exposures on the human skin. In vivo measurements with confocal microscopy. Photodermatol Photoimmunol Photomed 2004;20:27-32.
17. Gonzalez, S, González E, White WM, Rajadhyaksha M, Anderson RR. Allergic contact dermatitis: correlation of in vivo confocal imaging to routine histology. J Am Acad Dermatol 1999;40:708-713 (Pubitemid 29230357)
18. Pellacani G, Cesinaro AM, Seidenari S. In vivo confocal reflectance microscopy for the characterization of melanocytic nests and correlation with dermoscopy and histology. Br J Dermatol 2005;152:384-386 (Pubitemid 40343627)
19. Altintas MA, Altintas AA, Knobloch K, Guggenheim M, Zweifel CJ, Vogt PM. Differentiation of superficial-partial vs. deeppartial thickness burn injuries in vivo by confocal-laser-scanning microscopy. Burns 2009;35:80-86
20. Altintas MA, Altintas AA, Guggenheim M, Niederbichler AD, Knobloch K, Vogt PM. In vivo evaluation of histomorphological alterations in first degree burn injuries by means of confocal-laser-scanning microscopy-more than "virtual histology"? J Burn Care Res 2009;30:315-320
21. O'Reilly TJ, Spence RJ, Taylor RM, Scheulen JJ. Laser Doppler flowmetry evaluation of burn wound depth. J Burn Care Rehabil 1989;10:1-6.
22. Yeong EK, Mann R, Goldberg M, Engrav L, Heimbach D. Improved accuracy of burn wound assessment using laser Doppler. J Trauma 1996;40:956-61; discussion 961-962
23. Allgower M, Schoenenberger GA, Sparkes BG. Burning the largest immune organ. Burns, 1995;21 (Suppl 1):S7-S47.
24. Astner S, González E, Cheung AC, et al.. Non-invasive evaluation of the kinetics of allergic and irritant contact dermatitis. J Invest Dermatol 2005;124:351-359
25. Winter GD. Histological aspects of burn wound healing. Burns 1973;1:191-196
26. Johnson RM, Richard R. Partial-thickness burns: identification and management. Adv Skin Wound Care 2003;16: 178-87; quiz 188-189