Assessing mucosal immunity with new concepts and innovative, time-honored strategies

Nutrition Reviews

Volumn 67, Issue SUPPL. 2, 2009, Pages

  Erickson, Kent L ^a   Hubbard, Neil E ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

GALT assessment methods; Humanized immune system; Mouse models; Mucosal immunity; Toll like receptors

Indexed keywords

TOLL LIKE RECEPTOR;

ADOPTIVE TRANSFER; CONFERENCE PAPER; ENTERITIS; EX VIVO STUDY; GASTROINTESTINAL BIOPSY; HUMAN; HUMORAL IMMUNITY; IMMUNE STATUS; INNATE IMMUNITY; INTESTINE LYMPHATIC TISSUE; LYMPHOID TISSUE; MUCOSAL IMMUNITY; NONHUMAN; TRANSGENIC MOUSE; ANIMAL; BACTERIUM; DISEASE MODEL; GASTROINTESTINAL DISEASE; GASTROINTESTINAL TRACT; IMMUNOLOGY; MICROBIOLOGY; MOUSE; PHYSIOLOGY; REVIEW;

ANIMALS; BACTERIA; DISEASE MODELS, ANIMAL; GASTROINTESTINAL DISEASES; GASTROINTESTINAL TRACT; HUMANS; IMMUNITY, MUCOSAL; LYMPHOID TISSUE; MICE; TOLL-LIKE RECEPTORS;

EID: 75349091437     PISSN: 00296643     EISSN: 17534887     Source Type: Journal    
DOI: 10.1111/j.1753-4887.2009.00238.x     Document Type: Conference Paper

References (31)

1. Neutra MR, Mantis NJ, Kraehenbuhl JP. Collaboration of epithelial cells with organized mucosal lymphoid tissues. Nat Immunol. 2001;2:1004-1009.
2. Corr SC, Gahan CC, Hill C. M-cells: Origin, morphology and role in mucosal immunity and microbial pathogenesis. FEMS Immunol Med Microbiol. 2008;52:2-12.
3. des Rieux A, Ragnarsson EG, Gullberg E, Preat V, Schneider YJ, Artursson P. Transport of nanoparticles across an in vitro model of the human intestinal follicle associated epithelium. Eur J Pharm Sci. 2005;25:455-465.
4. Rhee SH, ImE, Pothoulakis C. Toll-like receptor 5 engagement modulates tumor development and growth in a mouse xenograft model of human colon cancer. Gastroenterology. 2008;135:518-528.
5. Bai AP, Ouyang Q, Xiao XR, Li SF. Probiotics modulate inflammatory cytokine secretion from inflamed mucosa in active ulcerative colitis. Int J Clin Pract. 2006;60:284-288.
6. Bambou JC, Giraud A, Menard S, et al. In vitro and ex vivo activation of the TLR5 signaling pathway in intestinal epithelial cells by a commensal Escherichia coli strain. J Biol Chem. 2004;279:42984-42992.
7. Smith K, McCoy KD, Macpherson AJ. Use of axenic animals in studying the adaptation of mammals to their commensal intestinal microbiota. Semin Immunol. 2007;19:59-69.
8. Niess JH, Leithauser F, Adler G, Reimann J. Commensal gut flora drives the expansion of proinflammatory CD4 T cells in the colonic lamina propria under normal and inflammatory conditions. J Immunol. 2008;180:559-568.
9. Menard O, Butel MJ, Gaboriau-Routhiau V, Waligora- Dupriet AJ. Gnotobiotic mouse immune response induced by Bifidobacterium sp. strains isolated frominfants. Appl Environ Microbiol. 2008;74:660-666.
10. Chen CC, Chiu CH, Lin TY, Ning Shi H, Walker WA. Effect of probiotics L. acidophilus on C. rodentium colitis: The role of dendritic cells. Pediatr Res. 2009;65:169-175.
11. Legrand N, Weijer K, Spits H. Experimental model for the study of the human immune system. In: Ewbank J, Vivier E, eds. Innate Immunity. Totowa, NJ: Humana Press; 2008:65-82.
12. Legrand N, Weijer K, Spits H. Experimental models to study development and function of the human immune system in vivo. J Immunol. 2006;176:2053-2058.
13. Chicha L, Tussiwand R, Traggiai E, et al. Human adaptive immune system Rag2-/-gamma(c)-/- mice. Ann N Y Acad Sci. 2005;1044:236-243.
14. Choi BK, Joo SY, Moon C, et al. Reconstitution of human lymphocytes following ex vivo expansion of human umbilical cord blood CD34+ cells and transplantation in Rag2-/- gamma c-/- mice model. Transplant Proc. 2008;40:2655-2660.
15. Giassi LJ, Pearson T, Shultz LD, et al. Expanded CD34+ human umbilical cord blood cells generatemultiple lymphohematopoietic lineages in NOD-scid IL2rgamma(null) mice. Exp Biol Med (Maywood). 2008;233:997-1012.
16. Hofer U, Baenziger S, Heikenwalder M, et al. RAG2-/- gamma(c)-/- mice transplanted with CD34+ cells from human cord blood show low levels of intestinal engraftment and are resistant to rectal transmission of human immunodeficiency virus. J Virol. 2008;82:12145-12153.
17. Cocco M, Bellan C, Tussiwand R, et al. CD34+ cord blood celltransplanted Rag2-/- gamma(c)-/- mice as a model for Epstein-Barr virus infection. Am J Pathol. 2008;173:1369-1378.
18. Kuruvilla JG, Troyer RM, Devi S, Akkina R. Dengue virus infection and immune response in humanized RAG2(-/-) gamma(c)(-/-) (RAG-hu) mice. Virology. 2007;369:143-152.
19. Melkus MW, Estes JD, Padgett-Thomas A, et al. Humanized mice mount specific adaptive and innate immune responses to EBV and TSST-1. Nat Med. 2006;12:1316-1322.
20. Sun Z, Denton PW, Estes JD, et al. Intrarectal transmission, systemic infection, and CD4+ T cell depletion in humanized mice infected with HIV-1. J Exp Med. 2007;204:705-714.
21. Denton PW, Estes JD, Sun Z, et al. Antiretroviral pre-exposure prophylaxis prevents vaginal transmission of HIV-1 in humanized BLT mice. PLoS Med. 2008;5:e16.
22. Shang L, Fukata M, Thirunarayanan N, et al. Toll-like receptor signaling in small intestinal epithelium promotes B-cell recruitment and IgA production in lamina propria. Gastroenterology. 2008;135:529-538.
23. Elson CO, Cong Y, McCracken VJ, Dimmitt RA, Lorenz RG, Weaver CT. Experimental models of inflammatory bowel disease reveal innate, adaptive, and regulatory mechanisms of host dialogue with the microbiota. Immunol Rev. 2005; 206:260-276.
24. Ostanin DV, Boa R, Koboziev I, et al. T-cell transfer model of chronic colitis: Concepts, considerations and tricks of the trade. Am J Physiol Gastrointest Liver Physiol. 2009;296: G135-G146.
25. Chapkin RS, Kamen BA, Callaway ES, et al. Use of a novel genetic mouse model to investigate the role of folate in colitis-associated colon cancer. J Nutr Biochem. 2009;20:649-655.
26. Qualls JE, Tuna H, Kaplan AM, Cohen DA. Suppression of experimental colitis in mice by CD11c(+) dendritic cells. Inflamm Bowel Dis. 2009;15:236-247.
27. Laroux FS, Norris HH, Houghton J, et al. Regulation of chronic colitis in athymic nu/nu (nude) mice. Int Immunol. 2004;16:77-89.
28. Ostanin DV, Pavlick KP, Bharwani S, et al. T cell-induced inflammation of the small and large intestine in immunodeficient mice. Am J Physiol Gastrointest Liver Physiol. 2006; 290:G109-G119.
29. Shacklett BL, Critchfield JW, Lemongello D. Isolating mucosal lymphocytes from biopsy tissue for cellular immunology assays. In: Prasad VR, Kalpana GV, eds. HIV Protocols: Second Edition. Clifton, NJ: Humana Press; 2009:347-356.
30. Shacklett BL, Critchfield JW, Lemongello D. Quantifying HIV- 1-specific CD8 (+) T-cell responses using ELISPOT and cytokine flow cytometry. HIV Protocols: Second Edition. Clifton, NJ: Humana Press; 2009:359-374.
31. Critchfield JW, Lemongello D, Walker DH, et al. Multifunctional human immunodeficiency virus (HIV) gag-specific CD8+ T-cell responses in rectal mucosa and peripheral blood mononuclear cells during chronic HIV type 1 infection. J Virol. 2007;81:5460-5471.