Morphologic Features of Exertional Versus Nonexertional Sudden Death in Patients With Hypertrophic Cardiomyopathy

American Journal of Cardiology

Volumn 105, Issue 4, 2010, Pages 532-537

  Tavora, Fabio ^a   Cresswell, Nathaniel ^a   Li, Ling ^b   Ripple, Mary ^b   Fowler, David ^b   Burke, Allen ^a,b  

^a ARMED FORCES INSTITUTE OF PATHOLOGY   (United States)

^b UNIVERSITY OF MARYLAND   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA ADRENERGIC RECEPTOR BLOCKING AGENT;

ADULT; ARTICLE; ARTIFICIAL HEART PACEMAKER; AUTOPSY; CAUSE OF DEATH; CLINICAL FEATURE; CONTROLLED STUDY; DISEASE DURATION; EXERTIONAL SUDDEN DEATH; FEMALE; GENDER; HEART LEFT VENTRICLE OUTFLOW TRACT OBSTRUCTION; HEART WEIGHT; HISTOLOGY; HUMAN; HYPERTROPHIC CARDIOMYOPATHY; INCIDENCE; MAJOR CLINICAL STUDY; MALE; MORPHOLOGICAL TRAIT; NONEXERTIONAL SUDDEN DEATH; ONSET AGE; PATHOLOGY; PRIORITY JOURNAL; REST; SUDDEN DEATH; SYNCOPE;

ADOLESCENT; ADULT; AGE FACTORS; AGED; AUTOPSY; CARDIOMYOPATHY, HYPERTROPHIC; DEATH, SUDDEN, CARDIAC; FEMALE; HUMANS; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; ORGAN SIZE; PHYSICAL EXERTION; SEX DISTRIBUTION;

EID: 75349091262     PISSN: 00029149     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.amjcard.2009.10.022     Document Type: Article

References (17)

1. Maron B.J., Roberts W.C., and Epstein S.E. Sudden death in hypertrophic cardiomyopathy: a profile of 78 patients. Circulation 65 (1982) 1388-1394
2. Maron B.J., Wolfson J.K., and Roberts W.C. Relation between extent of cardiac muscle cell disorganization and left ventricular wall thickness in hypertrophic cardiomyopathy. Am J Cardiol 70 (1992) 785-790
3. Maki S., Ikeda H., Muro A., Yoshida N., Shibata A., Koga Y., and Imaizumi T. Predictors of sudden cardiac death in hypertrophic cardiomyopathy. Am J Cardiol 82 (1998) 774-778
4. Maron B.J., Maron M.S., Lesser J.R., Hauser R.G., Haas T.S., Harrigan C.J., Appelbaum E., Main M.L., and Roberts W.C. Sudden cardiac arrest in hypertrophic cardiomyopathy in the absence of conventional criteria for high risk status. Am J Cardiol 101 (2008) 544-547
5. Ahmad M., Afzal S., Malik I.A., Mushtaq S., and Mubarik A. An autopsy study of hypertrophic cardiomyopathy. J Pak Med Assoc 53 (2003) 459-462
6. Maron B.J., Shirani J., Poliac L.C., Mathenge R., Roberts W.C., and Mueller F.O. Sudden death in young competitive athletes. Clinical, demographic, and pathological profiles. JAMA 276 (1996) 199-204
7. Maron B.J., Kragel A.H., and Roberts W.C. Sudden death in hypertrophic cardiomyopathy with normal left ventricular mass. Br Heart J 63 (1990) 308-310
8. Roberts C.S., and Roberts W.C. Morphologic features. In: Zipes D.P., and Rowlands D.J. (Eds). Progress in Cardiology (1989), Lea and Febiger, Philadelphia 3-32
9. Litovsky S.H., and Rose A.G. Clinicopathologic heterogeneity in hypertrophic cardiomyopathy with regard to age, asymmetric septal hypertrophy, and concentric hypertrophy beyond the pediatric age group. Arch Pathol Lab Med 122 (1998) 434-441
10. Phadke R.S., Vaideeswar P., Mittal B., and Deshpande J. Hypertrophic cardiomyopathy: an autopsy analysis of 14 cases. J Postgrad Med 47 (2001) 165-170
11. Morimoto S., Sekiguchi M., Hiramitsu S., Uemura A., Nishikawa T., and Hishida H. Contribution of cardiac muscle cell disorganization to the clinical features of hypertrophic cardiomyopathy. Heart Vessels 15 (2000) 149-158
12. Maron B.J., Carney K.P., Lever H.M., Lewis J.F., Barac I., Casey S.A., and Sherrid M.V. Relationship of race to sudden cardiac death in competitive athletes with hypertrophic cardiomyopathy. J Am Coll Cardiol 41 (2003) 974-980
13. Blauwet L.A., Ackerman M.J., Edwards W.D., Riehle D.L., and Ommen S.R. Myocardial fibrosis in patients with symptomatic obstructive hypertrophic cardiomyopathy: correlation with echocardiographic measurements, sarcomeric genotypes, and pro-left ventricular hypertrophy polymorphisms involving the renin-angiotensin-aldosterone system. Cardiovasc Pathol 18 (2009) 262-268
14. Harikrishnan S., Sunder K.R., Tharakan J., Titus T., Bhat A., Sivasankaran S., and Bimal F. Clinical and angiographic profile and follow-up of myocardial bridges: a study of 21 cases. Indian Heart J 51 (1999) 503-507
15. Rozenberg V.D., and Nepomnyashchikh L.M. Pathomorphology and pathogenic role of myocardial bridges in sudden cardiac death. Bull Exp Biol Med 138 (2004) 87-92
16. Klues H.G., Schiffers A., and Maron B.J. Phenotypic spectrum and patterns of left ventricular hypertrophy in hypertrophic cardiomyopathy: morphologic observations and significance as assessed by two-dimensional echocardiography in 600 patients. J Am Coll Cardiol 26 (1995) 1699-1708
17. Anan R., Shono H., Kisanuki A., Arima S., Nakao S., and Tanaka H. Patients with familial hypertrophic cardiomyopathy caused by a Phe110Ile missense mutation in the cardiac troponin T gene have variable cardiac morphologies and a favorable prognosis. Circulation 98 (1998) 391-397