A new cytotoxic flabelliferin from palmyrah (Borassus flabellifer L.) flour

Journal of the National Science Foundation of Sri Lanka

Volumn 37, Issue 4, 2009, Pages 269-271

  Keerthi, A A P ^a   Ekanayake, S ^a   Premakumara, G A S ^b  

^a Faculty of Medical Sciences   (Sri Lanka)

^b INDUSTRIAL TECHNOLOGY INSTITUTE   (Sri Lanka)

Author keywords

Cytotoxic; Flabelliferins; Melanoma cell line; Palmyrah; Spirosterol; Tetraglycoside

Indexed keywords

EID: 75349090603     PISSN: 13914588     EISSN: None     Source Type: Journal    
DOI: 10.4038/jnsfsr.v37i4.1474     Document Type: Article

References (13)

1. Anderson P.H. & Poulson E. (1985). Mutagenicity of flour from palmyrah palm (Borassus flabellifer) in Salmonella typhimurium and Escherichia coli. Cancer Letters 26: 118-119.
2. Kangwngpong D., Arseculeratne S.N. & Sirisinha S. (1981). Clastogenic effect of aqueous extracts of palmyrah (Borassus flabellifer) flour on human blood lymphocytes. Mutation Research 89: 63-68.
3. 3. Révész L., Hiestand P., LaVechia L., Naef R., Naegeli H.U., Oberer L. & Roth H.J. (1999). Isolation and synthesis of a novel immunosuppressive 17α-substituted dammarane from the flour of palmyrah palm (Borassus flabellifer), Bioorganic and Medicinal Chemistsry Letters 9(11): 1521-1526. (Pubitemid 29274189)
4. Keerthi A.A.P., Ekanayake S. & Jansz E.R. (2007). Larvicidal effects of a flabelliferin saponin from palmyrah flour on dengue mosquito Aedes spp. Journal of the National Science Foundation of Sri Lanka 35(2): 133-138.
5. Greig J.B., Kay S.J.E. & Bennetts R.J. (1980). A toxin from the palmyrah palm, Borassus flabellifer: partial purification and effects in rats. Food and Cosmetics Toxicology 18(5): 483-488.
6. Keerthi A.A.P., Jansz E.R. & Ekanayake S. (2009). Studies on a hyper-haemolytic compound of palmyrah flour (Odiyal). Vidyodaya Journal of Science 14:79-84.
7. Wickramasekara N.T. & Jansz E.R. (2003). The range of steroidal saponins of palmyrah flour: could they contribute to toxic effect on consumers? Journal of Science, Eastern University, Sri Lanka 3(1):11-18.
8. 8. Jansz E.R., Nikawala J.K., Gooneratne J. & Theivendirarajah K. (1994). Studies on the bitter principle and debittering of palmyrah fruit pulp. Journal of the Science of Food and Agriculture 65:185-189. (Pubitemid 2096150)
9. 9. Yoshikawa M., Xu F., Morikawa T., Pongpiriyadacha Y., Nakamuru S., Asao Y., Kumahara A. & Matsuda H. (2007). Medicinal Flowers.XII1). New spirostane-type steroid saponins with antidiabetogenic activity from Borassus flabellifer. Chemical Pharmacological Bulletin 55(2): 308-316. (Pubitemid 46246826)
10. Monks A., Scudiero D., Skehan P., Shoemaker R., Paull K., Vistica D., Hose C., Langley J., Cronise P., Vaigro-Wolff A., Gray-Goodrich M., Campbell H., Mayo J. & Boyd M. (1991). Feasibility of a high-flux anticancer drug screen using a diverse panel of cultured human tumor cell lines. Journal of the National Cancer Institute 88(11): 757-765.
11. Ariyasena D.D., Jansz E.R., Janssen P.E. & Baeckstrom P. (2002). Structural elucidation of the antimicrobial flabelliferin from palmyrah (Borassus flabellifer L.) fruit pulp. Chemistry in Sri Lanka 19:13-14.
12. Kim H.K., Jeon W.K. & Ko B.S. (2001). Flavanone glycosides from Citrus junos and their anti-influenza virus activity. Planta Medica 67: 548-549.
13. Ye W., Zhang Q., Pen G., Zhao S. & Che C.T. (2001). Two unusual oleanane saponins from Anemone anhuiensis. Planta Medica 67: 590-592.